Could well-established, widely available, and simple laboratory techniques explain a laboratory origin of SARS-CoV-2?
Braz J Infect Dis. 2023 Oct 3:102808. doi: 10.1016/j.bjid.2023.102808. Online ahead of print.NO ABSTRACTPMID:37802129 | DOI:10.1016/j.bjid.2023.102808 (Source: Braz J Infect Dis)
Source: Braz J Infect Dis - October 6, 2023 Category: Infectious Diseases Authors: Robert M Lloyd James R Hunter Ricardo Sobhie Diaz Mauro Schechter Source Type: research

Weight gain in patients starting Dolutegravir-based ART according to baseline CD4 count after 48 weeks of follow up
CONCLUSIONS: Weight gain in the present study indicates a "return to health" phenomenon. Excessive weight gain was more frequent in women.PMID:37788801 | DOI:10.1016/j.bjid.2023.102807 (Source: Braz J Infect Dis)
Source: Braz J Infect Dis - October 3, 2023 Category: Infectious Diseases Authors: Érico C Cardoso-Neto Eduardo Martins Netto Carlos Brites Source Type: research

Weight gain in patients starting Dolutegravir-based ART according to baseline CD4 count after 48 weeks of follow up
CONCLUSIONS: Weight gain in the present study indicates a "return to health" phenomenon. Excessive weight gain was more frequent in women.PMID:37788801 | DOI:10.1016/j.bjid.2023.102807 (Source: Braz J Infect Dis)
Source: Braz J Infect Dis - October 3, 2023 Category: Infectious Diseases Authors: Érico C Cardoso-Neto Eduardo Martins Netto Carlos Brites Source Type: research

Weight gain in patients starting Dolutegravir-based ART according to baseline CD4 count after 48 weeks of follow up
CONCLUSIONS: Weight gain in the present study indicates a "return to health" phenomenon. Excessive weight gain was more frequent in women.PMID:37788801 | DOI:10.1016/j.bjid.2023.102807 (Source: Braz J Infect Dis)
Source: Braz J Infect Dis - October 3, 2023 Category: Infectious Diseases Authors: Érico C Cardoso-Neto Eduardo Martins Netto Carlos Brites Source Type: research

Efficacy and safety of preemptive therapy for cytomegalovirus end-organ disease in people living with HIV: a systematic review and meta-analysis
CONCLUSIONS: Preemptive therapy could be a potential option for preventing CMV EOD in people living with HIV.PMID:37777185 | DOI:10.1016/j.bjid.2023.102805 (Source: Braz J Infect Dis)
Source: Braz J Infect Dis - September 30, 2023 Category: Infectious Diseases Authors: C ándida Díaz-Brochero Laura Cristina Nocua-B áez Martha Carolina Valderrama-Rios Jorge Alberto Cort és Source Type: research

Efficacy and safety of preemptive therapy for cytomegalovirus end-organ disease in people living with HIV: a systematic review and meta-analysis
CONCLUSIONS: Preemptive therapy could be a potential option for preventing CMV EOD in people living with HIV.PMID:37777185 | DOI:10.1016/j.bjid.2023.102805 (Source: Braz J Infect Dis)
Source: Braz J Infect Dis - September 30, 2023 Category: Infectious Diseases Authors: C ándida Díaz-Brochero Laura Cristina Nocua-B áez Martha Carolina Valderrama-Rios Jorge Alberto Cort és Source Type: research

Efficacy and safety of preemptive therapy for cytomegalovirus end-organ disease in people living with HIV: a systematic review and meta-analysis
CONCLUSIONS: Preemptive therapy could be a potential option for preventing CMV EOD in people living with HIV.PMID:37777185 | DOI:10.1016/j.bjid.2023.102805 (Source: Braz J Infect Dis)
Source: Braz J Infect Dis - September 30, 2023 Category: Infectious Diseases Authors: C ándida Díaz-Brochero Laura Cristina Nocua-B áez Martha Carolina Valderrama-Rios Jorge Alberto Cort és Source Type: research

Real-time PCR in the diagnosis of congenital toxoplasmosis
Braz J Infect Dis. 2023 Sep 21;27(5):102804. doi: 10.1016/j.bjid.2023.102804. Online ahead of print.ABSTRACTThe diagnosis of congenital toxoplasmosis presents limitations and therefore new options are necessary. The analysis of amniotic fluid by real-time PCR has already proved effective for confirmation of fetal infection. However, its performance in other biological samples is not clear yet. The aim of this study is to better understand the role of real-time PCR in the blood of the mother and newborn as well as in the amniotic fluid and placenta in the diagnosis of congenital toxoplasmosis. This is a descriptive cohort s...
Source: Braz J Infect Dis - September 24, 2023 Category: Infectious Diseases Authors: Bianca Balzano De La Fuente Villar Leonardo Henrique Ferreira Gomes Elyzabeth Avvad Portari Carla Nasser Patrocinio Ramos Danielle Nascimento Rocha Jos é Paulo Pereira Elizabeth de Souza Neves Let ícia da Cunha Guida Source Type: research

Real-time PCR in the diagnosis of congenital toxoplasmosis
Braz J Infect Dis. 2023 Sep 21:102804. doi: 10.1016/j.bjid.2023.102804. Online ahead of print.ABSTRACTThe diagnosis of congenital toxoplasmosis presents limitations and therefore new options are necessary. The analysis of amniotic fluid by real-time PCR has already proved effective for confirmation of fetal infection. However, its performance in other biological samples is not clear yet. The aim of this study is to better understand the role of real-time PCR in the blood of the mother and newborn as well as in the amniotic fluid and placenta in the diagnosis of congenital toxoplasmosis. This is a descriptive cohort study o...
Source: Braz J Infect Dis - September 24, 2023 Category: Infectious Diseases Authors: Bianca Balzano De La Fuente Villar Leonardo Henrique Ferreira Gomes Elyzabeth Avvad Portari Carla Nasser Patrocinio Ramos Danielle Nascimento Rocha Jos é Paulo Pereira Junior Elizabeth de Souza Neves Let ícia da Cunha Guida Source Type: research

Real-time PCR in the diagnosis of congenital toxoplasmosis
Braz J Infect Dis. 2023 Sep 21:102804. doi: 10.1016/j.bjid.2023.102804. Online ahead of print.ABSTRACTThe diagnosis of congenital toxoplasmosis presents limitations and therefore new options are necessary. The analysis of amniotic fluid by real-time PCR has already proved effective for confirmation of fetal infection. However, its performance in other biological samples is not clear yet. The aim of this study is to better understand the role of real-time PCR in the blood of the mother and newborn as well as in the amniotic fluid and placenta in the diagnosis of congenital toxoplasmosis. This is a descriptive cohort study o...
Source: Braz J Infect Dis - September 24, 2023 Category: Infectious Diseases Authors: Bianca Balzano De La Fuente Villar Leonardo Henrique Ferreira Gomes Elyzabeth Avvad Portari Carla Nasser Patrocinio Ramos Danielle Nascimento Rocha Jos é Paulo Pereira Junior Elizabeth de Souza Neves Let ícia da Cunha Guida Source Type: research

Real-time PCR in the diagnosis of congenital toxoplasmosis
Braz J Infect Dis. 2023 Sep 21:102804. doi: 10.1016/j.bjid.2023.102804. Online ahead of print.ABSTRACTThe diagnosis of congenital toxoplasmosis presents limitations and therefore new options are necessary. The analysis of amniotic fluid by real-time PCR has already proved effective for confirmation of fetal infection. However, its performance in other biological samples is not clear yet. The aim of this study is to better understand the role of real-time PCR in the blood of the mother and newborn as well as in the amniotic fluid and placenta in the diagnosis of congenital toxoplasmosis. This is a descriptive cohort study o...
Source: Braz J Infect Dis - September 24, 2023 Category: Infectious Diseases Authors: Bianca Balzano De La Fuente Villar Leonardo Henrique Ferreira Gomes Elyzabeth Avvad Portari Carla Nasser Patrocinio Ramos Danielle Nascimento Rocha Jos é Paulo Pereira Junior Elizabeth de Souza Neves Let ícia da Cunha Guida Source Type: research

Real-time PCR in the diagnosis of congenital toxoplasmosis
Braz J Infect Dis. 2023 Sep 21:102804. doi: 10.1016/j.bjid.2023.102804. Online ahead of print.ABSTRACTThe diagnosis of congenital toxoplasmosis presents limitations and therefore new options are necessary. The analysis of amniotic fluid by real-time PCR has already proved effective for confirmation of fetal infection. However, its performance in other biological samples is not clear yet. The aim of this study is to better understand the role of real-time PCR in the blood of the mother and newborn as well as in the amniotic fluid and placenta in the diagnosis of congenital toxoplasmosis. This is a descriptive cohort study o...
Source: Braz J Infect Dis - September 24, 2023 Category: Infectious Diseases Authors: Bianca Balzano De La Fuente Villar Leonardo Henrique Ferreira Gomes Elyzabeth Avvad Portari Carla Nasser Patrocinio Ramos Danielle Nascimento Rocha Jos é Paulo Pereira Junior Elizabeth de Souza Neves Let ícia da Cunha Guida Source Type: research

Significance of Aspergillus spp. isolation in defining cases of COVID-19 Associated Pulmonary Aspergillosis - CAPA
In this study, Aspergillus spp. isolation in respiratory specimens from patients with COVID-19 was evaluated for identifying cases of CAPA. In 2020‒2021, 17 Aspergillus spp. were isolated from 15 COVID-19 patients admitted to a university hospital in Brazil. Patient records were retrospectively reviewed to obtain clinical-epidemiological data and other markers of Aspergillus spp. infection and then compared with the ECMM/ISHAM criteria for defining CAPA. Probable CAPA was defined in 5/10 patients, who had Aspergillus spp. isolated from Bronchoalveolar Lavage (BAL) or a positive galactomannan blood test. Additionally, ant...
Source: Braz J Infect Dis - July 28, 2023 Category: Infectious Diseases Authors: Tiago Alexandre Cocio Lumena Pereira Machado Siqueira Katie Cristina Takeuti Riciluca Viviane Mazo Favero Gimenes T ânia Sueli de Andrade Gil Benard Roberto Mart ínez Valdes Roberto Bollela Source Type: research

Significance of Aspergillus spp. isolation in defining cases of COVID-19 Associated Pulmonary Aspergillosis - CAPA
In this study, Aspergillus spp. isolation in respiratory specimens from patients with COVID-19 was evaluated for identifying cases of CAPA. In 2020‒2021, 17 Aspergillus spp. were isolated from 15 COVID-19 patients admitted to a university hospital in Brazil. Patient records were retrospectively reviewed to obtain clinical-epidemiological data and other markers of Aspergillus spp. infection and then compared with the ECMM/ISHAM criteria for defining CAPA. Probable CAPA was defined in 5/10 patients, who had Aspergillus spp. isolated from Bronchoalveolar Lavage (BAL) or a positive galactomannan blood test. Additionally, ant...
Source: Braz J Infect Dis - July 28, 2023 Category: Infectious Diseases Authors: Tiago Alexandre Cocio Lumena Pereira Machado Siqueira Katie Cristina Takeuti Riciluca Viviane Mazo Favero Gimenes T ânia Sueli de Andrade Gil Benard Roberto Mart ínez Valdes Roberto Bollela Source Type: research

Significance of Aspergillus spp. isolation in defining cases of COVID-19 Associated Pulmonary Aspergillosis - CAPA
In this study, Aspergillus spp. isolation in respiratory specimens from patients with COVID-19 was evaluated for identifying cases of CAPA. In 2020‒2021, 17 Aspergillus spp. were isolated from 15 COVID-19 patients admitted to a university hospital in Brazil. Patient records were retrospectively reviewed to obtain clinical-epidemiological data and other markers of Aspergillus spp. infection and then compared with the ECMM/ISHAM criteria for defining CAPA. Probable CAPA was defined in 5/10 patients, who had Aspergillus spp. isolated from Bronchoalveolar Lavage (BAL) or a positive galactomannan blood test. Additionally, ant...
Source: Braz J Infect Dis - July 28, 2023 Category: Infectious Diseases Authors: Tiago Alexandre Cocio Lumena Pereira Machado Siqueira Katie Cristina Takeuti Riciluca Viviane Mazo Favero Gimenes T ânia Sueli de Andrade Gil Benard Roberto Mart ínez Valdes Roberto Bollela Source Type: research