Significantly enhanced lung metastasis and reduced organ NK cell functions in diet-induced obese rats
ConclusionsWe conclude that induction of obesity in F344-rats leads to reduced lung NK cell function against tumor cells and results in significantly enhanced lung metastasis as compared to lean animals. It can be hypothesized that obesity-induced altered NK cell functions play an important role in cancer growth and metastasis. (Source: BMC Obesity)
Source: BMC Obesity - July 3, 2017 Category: Eating Disorders & Weight Management Source Type: research

Association between serum uric acid and metabolic syndrome components in prepubertal obese children (Tanner Stage I) from Nuevo Le ón, Mexico - a preliminary study
ConclusionsThe findings of this study clearly indicate a positive relationship between uric acid and MetS and its components in pre-pubertal obese children with Tanner stage I and ≤9 years of age. (Source: BMC Obesity)
Source: BMC Obesity - July 3, 2017 Category: Eating Disorders & Weight Management Source Type: research

Accuracy of anthropometric measurements by general practitioners in overweight and obese patients
ConclusionsAbdominal obesity measurements are particularly inaccurate when GPs use these measurements to assess overweight and obese patients. These findings add further strength to recommendations for GPs to favour use of general obesity measurements in daily practice, particularly when assessing overweight or obese patients. (Source: BMC Obesity)
Source: BMC Obesity - June 29, 2017 Category: Eating Disorders & Weight Management Source Type: research

Prevalence and predictors of irritable bowel syndrome in patients with morbid obesity: a cross-sectional study
ConclusionsAt one of the two obesity centers, the prevalence of irritable bowel syndrome was threefold higher than in the general population in the same region. The high prevalence appears to be related to dietary differences or altered absorption or metabolism of fat. Attention to irritable bowel syndrome is important in the care of patients with morbid obesity. (Source: BMC Obesity)
Source: BMC Obesity - June 29, 2017 Category: Eating Disorders & Weight Management Source Type: research

Gender, alexithymia and physical inactivity associated with abdominal obesity in type 1 diabetes mellitus: a cross sectional study at a secondary care hospital diabetes clinic
ConclusionsAlexithymia, particularly the alexithymia subfactor “difficulty identifying feelings”, physical inactivity, and women, as well as cardiovascular complications were associated with abdominal obesity. As abdominal obesity is detrimental in diabetes due to its association with cardiovascular complications, our results suggest two risk factor treatme nt targets: increased emotional awareness and increased physical activity. (Source: BMC Obesity)
Source: BMC Obesity - June 2, 2017 Category: Eating Disorders & Weight Management Source Type: research

Overweight and obesity prevalence among public servants in Nadowli district, Ghana, and associated risk factors: a cross-sectional study
ConclusionPopulation-based interventions are needed to promote nutritious food selection and consumption, physical activity and healthy life styles. We also recommend that age and gender-specific interventions should be designed and implemented by relevant authorities to promote and support healthy living and healthy-lifestyles at home and in workplaces. (Source: BMC Obesity)
Source: BMC Obesity - June 1, 2017 Category: Eating Disorders & Weight Management Source Type: research

Childhood overweight, obesity and associated factors among primary school children in dire dawa, eastern Ethiopia; a cross-sectional study
ConclusionOverweight/obesity in children is on alarming stage in the study area. Therefore, more attention should be given to creating awareness about healthy diet and improving life style through school and public media in collaboration with concerned bodies. (Source: BMC Obesity)
Source: BMC Obesity - June 1, 2017 Category: Eating Disorders & Weight Management Source Type: research

The effects of dietary macronutrient composition on lipid metabolism-associated factor gene expression in the adipose tissue of chickens are influenced by fasting and refeeding
ConclusionsThe decreased adipose tissue deposition in chicks fed the HP diet is likely explained by decreased rates of adipogenesis. Consumption of the HF diet was associated with greater adipose tissue deposition and larger adipocytes, likely as a result of greater rates of adipocyte hypertrophy. The depot-dependent effects of diet and fasting on gene expression may help explain mechanisms underlying metabolic distinctions among subcutaneous and visceral fat depots in humans. (Source: BMC Obesity)
Source: BMC Obesity - May 10, 2017 Category: Eating Disorders & Weight Management Source Type: research

Understanding perceived determinants of nurses ’ eating and physical activity behaviour: a theory-informed qualitative interview study
ConclusionsThis study used a theory-informed approach by applying the TDF to identify the key perceived determinants of nurses ’ eating and physical activity behaviour. The findings suggest that future efforts to change nurses’ eating and physical activity behaviours should consider targeting a broad range of environmental, interpersonal and intrapersonal level factors, consistent with a socio-ecological perspective. (Source: BMC Obesity)
Source: BMC Obesity - May 9, 2017 Category: Eating Disorders & Weight Management Source Type: research

Increases in waist circumference independent of weight in Mongolia over the last decade: the Mongolian STEPS surveys
ConclusionOver the last decade, among Mongolian adults, there has been substantially greater increase in WC and the prevalence of abdominal obesity than would be expected from increases in weight. Women are at greater risk than men of being misclassified as not obese if obesity is defined using BMI only. Obesity should be monitored using WC in addition to BMI to ensure the prevalence of obesity is not underestimated. (Source: BMC Obesity)
Source: BMC Obesity - May 8, 2017 Category: Eating Disorders and Weight Management Source Type: research

The effect of a medical opinion on self-perceptions of weight for Mexican adults: perception of change and cognitive biases
ConclusionsObese and overweight Mexican adults not only underestimated their weight, but also, could not accurately judge changes in weight. For example, an increase of 5  kg is imagined, in terms of self-image, to be considerably less. It was seen that an identification of obesity by a health care professional did not improve ability to judge weight but, rather, served as a new anchor from which the identified obese judge their weight, suggesting that even those id entified obese who have lost weight, perceive their weight to be greater than it actually is. We believe that these results can be explained in terms of two c...
Source: BMC Obesity - May 3, 2017 Category: Eating Disorders and Weight Management Source Type: research

The association of self-regulation with weight loss maintenance after an intensive combined lifestyle intervention for children and adolescents with severe obesity
ConclusionsThe ability to self-regulate after an intensive, partly inpatient, multidisciplinary one year intervention for severe obesity in children and adolescents was not associated with the ability to maintain the achieved weight loss during the following year. Factors that explain the large range of long term outcomes need to be elucidated.Trial registrationNetherlands Trial Register (NTR1678, registered 20-Feb-2009). (Source: BMC Obesity)
Source: BMC Obesity - April 25, 2017 Category: Eating Disorders and Weight Management Source Type: research

An evaluation of low volume high-intensity intermittent training (HIIT) for health risk reduction in overweight and obese men
ConclusionBoth 6 and 4 sessions of HIIT performed over a 2-week period are ineffective in improving selected health markers within an overweight and obese cohort.Trial registrationThis trial reports data from human participants and was retrospectively registered on 22/02/2017 with the ISRCTN registry, trial numberISRCTN90672085. (Source: BMC Obesity)
Source: BMC Obesity - April 19, 2017 Category: Eating Disorders and Weight Management Source Type: research

Association of gene coding variation and resting metabolic rate in a multi-ethnic sample of children and adults
ConclusionsThese nominal associations were robust to adjustment for BMI. The most significant variants were also evaluated using phenome-wide association to evaluate pleiotropy, and genetically predicted gene expression using the summary statistics implicated loci related to in obesity and body composition. These results merit further examination in larger cohorts of children and adults. (Source: BMC Obesity)
Source: BMC Obesity - April 5, 2017 Category: Eating Disorders and Weight Management Source Type: research

Urinary biomarkers as indicator of chronic inflammation and endothelial dysfunction in obese adolescents
ConclusionUrinary TNF-alpha is significantly elevated in obese adolescents and correlates with urinary ET-1, which is recognized as a biomarker for endothelial dysfunction. Since obesity is a chronic inflammatory state, elevated urinary TNF-alpha might be used as a non invasive tool to monitor the level of that inflammation. (Source: BMC Obesity)
Source: BMC Obesity - March 22, 2017 Category: Eating Disorders and Weight Management Source Type: research