(Difluoromethyl)trimethylsilane (TMSCHF 2 ): A Useful Difluoromethylating Nucleophilic Source
Margherita Miele, Vittorio Pace
(Difluoromethyl)trimethylsilane (TMSCHF2) is a useful difluoromethylating nucleophilic source. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - May 19, 2021 Category: Chemistry Authors: Margherita Miele Vittorio Pace Source Type: research
The Future of Retrosynthesis and Synthetic Planning: Algorithmic, Humanistic or the Interplay?
Craig M. Williams, Madeleine A. Dallaston
Will the computer ever compete with human retrosynthetic design and the art of organic synthesis? (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - May 12, 2021 Category: Chemistry Authors: Craig M. Williams Madeleine A. Dallaston Source Type: research
Crystal Engineering of Sterically Shielded Hexa-peri-hexabenzocoronenes
David Reger, Frank Hampel, Norbert Jux
Solid-state properties of organic materials are crucial for applications, but the aggregation is often difficult to predict and to adjust. In this work we investigated the packing of sterically shielded hexa-peri-hexabenzocoronene derivatives and present the manipulation of their aggregation with various functional groups. These findings will improve the understanding of packing behaviour in polycyclic aromatic hydrocarbons and nanographenes. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - May 6, 2021 Category: Chemistry Authors: David Reger Frank Hampel Norbert Jux Source Type: research
The Synthesis and Biological Evaluation of Some C-9 and C-10 Substituted Derivatives of the RNA Polymerase I Transcription Inhibitor CX-5461
Madushani Amarasiri, Yen Vo, Michael G. Gardiner, Perlita Poh, Priscilla Soo, Megan Pavy, Nadine Hein, Rita Ferreira, Katherine M. Hannan, Ross D. Hannan, Martin G. Banwell
Compound 3 is an active analogue of the RNA polymerase I transcription inhibitor CX-5461 but four click products from the former are not. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - April 16, 2021 Category: Chemistry Authors: Madushani Amarasiri Yen Vo Michael G. Gardiner Perlita Poh Priscilla Soo Megan Pavy Nadine Hein Rita Ferreira Katherine M. Hannan Ross D. Hannan Martin G. Banwell Source Type: research
Evaluation of a Continuous-Flow Photo-Bromination Using N-Bromosuccinimide for Use in Chemical Manufacture
Matthew Waterford, Simon Saubern, Christian H. Hornung
Simple photo-bromination chemistry can be scaled up in a flow reactor using modern LED-based equipment, and crucially combined with in-line workup and purification. This integrated multi-stage operation provides a novel solution for the chemical manufacturing industry to use photochemistry and continuous flow reactors on an industrial scale. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - April 9, 2021 Category: Chemistry Authors: Matthew Waterford Simon Saubern Christian H. Hornung Source Type: research
Structure and Facile Synthesis of Proton-Conducting [Fe(CN) 6 ] 3 & #x2013; Bridged Cd-Complex
Wei-Min Ding, Yao Zhao, Hong-Yu Zhang, Feng-Ming Zhang
A Cd2+ based coordination polymer material featuring 3D network was synthesized by a facile stirring method for water-mediated proton conduction. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - April 9, 2021 Category: Chemistry Authors: Wei-Min Ding Yao Zhao Hong-Yu Zhang Feng-Ming Zhang Source Type: research
A Simple Isocratic HPLC Method for the Quantitation of 17 Cannabinoids
Peter Galettis, Michelle Williams, Rebecca Gordon, Jennifer H. Martin
This paper describes the optimal separation of 17 cannabinoids using an isocratic HPLC-UV method. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - April 8, 2021 Category: Chemistry Authors: Peter Galettis Michelle Williams Rebecca Gordon Jennifer H. Martin Source Type: research
Evaluation of Calcium Binding Capacity of Chelating Agents in Calcium Carbonate Suspension and Effects on Calcium Distribution of Calcium Chelating Agents
Mingyue Song, Leping Dang, Hongyuan Wei
The application of fluoride as an important active ingredient in calcium carbonate toothpaste is limited due to production of calcium fluoride precipitates. Adding chelators to the formula is a new method to increase the concentration of fluorine. The calcium binding capacity has led to an important role for chelators to reduce the activity of calcium. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - April 6, 2021 Category: Chemistry Authors: Mingyue Song Leping Dang Hongyuan Wei Source Type: research
Long-Chained Pyridinium N-Chloramines: Synthesis and Remarkable Biocidal Efficacies for Antibacterial Application
Lingdong Li, Dongxue Jia, Guangqing Zhang, Hanxue Ma
Long-chained pyridinium N-chloramines were synthesised by covalent linking N-Cl unit and alkyl chain via alkylation of 3-hydroxypyridine. Compared with previous pyridinium N-chloramine that lacks intact alkyl chains, the current long-chained N-chloramines exerted distinctively elevated biocidal efficacy, probably resulting from ‘synergistic’ biocidal action between N-Cl moiety and the long-chained pyridinium moiety. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - March 30, 2021 Category: Chemistry Authors: Lingdong Li Dongxue Jia Guangqing Zhang Hanxue Ma Source Type: research
The Chemistry of Cannabis and Cannabinoids
Peter J. Duggan
This Primer Review is designed to give a succinct overview of the chemistry of cannabis and cannabinoids. It is hoped that it will provide a useful resource for chemistry undergraduates, postgraduates and their instructors, and experienced chemists who require a comprehensive and up to date summary of the field. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - March 18, 2021 Category: Chemistry Authors: Peter J. Duggan Source Type: research
Conformers, Properties of the Anticancer Drug Plocabulin, and its Binding Mechanism with p-Glycoprotein: DFT and MD Studies
Xudong Lü, Yufei Ma, Yulian Tao, Fei Yan, Ce Song, Cuihong Wang, Meiling Zhang
The physical and chemical properties of anticancer drug plocabulin (PM060184) were studied by density functional theory (DFT). The anti-drug resistance mechanism of plocabulin was explored through its interaction with p-glycoprotein, the relative binding energy was calculated by MM/PBSA, and key amino acid residues were analysed. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - March 8, 2021 Category: Chemistry Authors: Xudong L & #xfc; Yufei Ma Yulian Tao Fei Yan Ce Song Cuihong Wang Meiling Zhang Source Type: research
The Synthesis of a Two-Photon Fluorescence Labelling Probe and its Immunochromatographic Strip for Rapid Diagnosis of COVID-19
Chibao Huang, Shuai Kang, Fuxun Yu, Zairong Wei
A two-photon fluorescence labelling probe synthesised here can be used to image COVID-19 in tissues, and its immunochromatographic strip (TPICS) can rapidly diagnose COVID-19. TPICS is much simpler than the nucleic acid detection method to shorten the detection period, and much more stable than the colloidal gold method to overcome uncertainty. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - February 25, 2021 Category: Chemistry Authors: Chibao Huang Shuai Kang Fuxun Yu Zairong Wei Source Type: research
Understanding the Polymer Rearrangement of pH-Responsive Nanoparticles
Nayeleh Deirram, Sarah S. Kermaniyan, Angus P. R. Johnston, Georgina K. Such
To develop a greater understanding of the dynamic nature of polymeric systems, pH-responsive nanoparticles were labelled with fluorescent dyes and then mixed with unlabelled nanoparticles. It was shown that the fluorescence intensity of the labelled nanoparticles remained constant at physiological pH (pH 7.4), suggesting limited migration of polymers between different nanoparticles. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - February 23, 2021 Category: Chemistry Authors: Nayeleh Deirram Sarah S. Kermaniyan Angus P. R. Johnston Georgina K. Such Source Type: research
N-Heterocyclic Carbenes & #x2013;Cu I Complexes as Catalysts: A Theoretical Insight
Nosheen Beig, Varsha Goyal, Raakhi Gupta, Raj K. Bansal
The electronic structures of five representative N-heterocyclic carbenes and their CuI complexes were investigated at the DFT (B3LYP/def2-SVP) level. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - February 4, 2021 Category: Chemistry Authors: Nosheen Beig Varsha Goyal Raakhi Gupta Raj K. Bansal Source Type: research
A Novel Synthesis of 2-Arylbenzimidazole and 2-Arylbenzothiazole Derivatives by MnO 2 /MOF-199
Elham Amouhadi, Razieh Fazaeli, Hamid Aliyan
The main objective of this research is to develop efficient and environmentally benign heterogeneous catalysts for synthesis of 2-arylbenzimidazole and 2-arylbenzothiazoles derivatives by MnO2/MOF-199. (Source: Australian Journal of Chemistry)
Source: Australian Journal of Chemistry - February 2, 2021 Category: Chemistry Authors: Elham Amouhadi Razieh Fazaeli Hamid Aliyan Source Type: research
