Interference of gut-brain-gonad axis originating from triclocarban exposure to parent zebrafish induces offspring embryonic development abnormality by up-regulation of maternal circSGOL1
Aquat Toxicol. 2023 Dec 1;266:106782. doi: 10.1016/j.aquatox.2023.106782. Online ahead of print.ABSTRACTTriclocarban (TCC) is a widely used antibacterial ingredient possessing acute toxicity effects; however, its chronic toxicity and underlying molecular mechanisms remain uncertain. Herein, we demonstrated that chronic TCC exposure affects the growth and development of adult zebrafish through inducing an intestinal flora disorder in the gut. The imbalance of intestinal flora caused functional barriers within the intestinal-brain-gonadal axis. This resulted in a series of anomalous nerve and motor behaviors, and reproductiv...
Source: Aquatic Toxicology - December 10, 2023 Category: Toxicology Authors: Huili Wang Xingcheng Liu Chenxi Zhao Jin Yan Zejun Wang Randy A Dahlgren Qiuhui Qian Xuedong Wang Source Type: research
Comparative study of domoic acid accumulation, isomer content and associated digestive subcellular processes in five marine invertebrate species
Aquat Toxicol. 2023 Dec 7;266:106793. doi: 10.1016/j.aquatox.2023.106793. Online ahead of print.ABSTRACTDespite the deleterious effects of the phycotoxin domoic acid (DA) on human health, and the permanent threat of blooms of the toxic Pseudo-nitzschia sp. over commercially important fishery-resources, knowledge regarding the physiological mechanisms behind the profound differences in accumulation and depuration of this toxin in contaminated invertebrates remain very scarce. In this work, a comparative analysis of accumulation, isomer content, and subcellular localization of DA in different invertebrate species was perform...
Source: Aquatic Toxicology - December 10, 2023 Category: Toxicology Authors: Jos é Luis García-Corona H élène Hegaret Malwenn Lassudrie Am élie Derrien Aouregan Terre-Terrillon Tom é Delaire Caroline Fabioux Source Type: research
Interference of gut-brain-gonad axis originating from triclocarban exposure to parent zebrafish induces offspring embryonic development abnormality by up-regulation of maternal circSGOL1
Aquat Toxicol. 2023 Dec 1;266:106782. doi: 10.1016/j.aquatox.2023.106782. Online ahead of print.ABSTRACTTriclocarban (TCC) is a widely used antibacterial ingredient possessing acute toxicity effects; however, its chronic toxicity and underlying molecular mechanisms remain uncertain. Herein, we demonstrated that chronic TCC exposure affects the growth and development of adult zebrafish through inducing an intestinal flora disorder in the gut. The imbalance of intestinal flora caused functional barriers within the intestinal-brain-gonadal axis. This resulted in a series of anomalous nerve and motor behaviors, and reproductiv...
Source: Aquatic Toxicology - December 10, 2023 Category: Toxicology Authors: Huili Wang Xingcheng Liu Chenxi Zhao Jin Yan Zejun Wang Randy A Dahlgren Qiuhui Qian Xuedong Wang Source Type: research
Comparative study of domoic acid accumulation, isomer content and associated digestive subcellular processes in five marine invertebrate species
Aquat Toxicol. 2023 Dec 7;266:106793. doi: 10.1016/j.aquatox.2023.106793. Online ahead of print.ABSTRACTDespite the deleterious effects of the phycotoxin domoic acid (DA) on human health, and the permanent threat of blooms of the toxic Pseudo-nitzschia sp. over commercially important fishery-resources, knowledge regarding the physiological mechanisms behind the profound differences in accumulation and depuration of this toxin in contaminated invertebrates remain very scarce. In this work, a comparative analysis of accumulation, isomer content, and subcellular localization of DA in different invertebrate species was perform...
Source: Aquatic Toxicology - December 10, 2023 Category: Toxicology Authors: Jos é Luis García-Corona H élène Hegaret Malwenn Lassudrie Am élie Derrien Aouregan Terre-Terrillon Tom é Delaire Caroline Fabioux Source Type: research
Interference of gut-brain-gonad axis originating from triclocarban exposure to parent zebrafish induces offspring embryonic development abnormality by up-regulation of maternal circSGOL1
Aquat Toxicol. 2023 Dec 1;266:106782. doi: 10.1016/j.aquatox.2023.106782. Online ahead of print.ABSTRACTTriclocarban (TCC) is a widely used antibacterial ingredient possessing acute toxicity effects; however, its chronic toxicity and underlying molecular mechanisms remain uncertain. Herein, we demonstrated that chronic TCC exposure affects the growth and development of adult zebrafish through inducing an intestinal flora disorder in the gut. The imbalance of intestinal flora caused functional barriers within the intestinal-brain-gonadal axis. This resulted in a series of anomalous nerve and motor behaviors, and reproductiv...
Source: Aquatic Toxicology - December 10, 2023 Category: Toxicology Authors: Huili Wang Xingcheng Liu Chenxi Zhao Jin Yan Zejun Wang Randy A Dahlgren Qiuhui Qian Xuedong Wang Source Type: research
Response of Propsilocerus akamusi (Diptera: Chironomidae) to the leachates from AMD-contaminated sediments: Implications for metal bioremediation of AMD-polluted areas
This study indicated the potential application of P. akamusi larvae in the metal bioremediation of AMD-polluted areas. STATEMENT OF ENVIRONMENTAL IMPLICATION: Acid mine drainage (AMD) is a global environmental problem related to coal mining activities. AMD pollution has become a long-term, worldwide issue for its interactive and complex stress factors. Bioremediation is an effective method to remove the metals of AMD from wastewater to prevent downstream pollution. However, the disadvantages of the slow growth rate, susceptibility to seasonal changes, difficult post-harvest management, and small biomass of hyperaccumulatin...
Source: Aquatic Toxicology - December 9, 2023 Category: Toxicology Authors: Xianyun Zheng Yuyu Li Jingchao Xu Yanchao Lu Source Type: research
Chronic toxicity of biodegradable microplastic (Polylactic acid) to Daphnia magna: A comparison with polyethylene terephthalate
This study aimed to assess ecotoxicity of biodegradable polylactic acid (PLA) MPs at concentration of 1 and 5 mgL-1 including a genetic analysis of Daphnia magna, and compared to effects of conventional polyethylene terephthalate (PET) MPs. The survival rate for D. magna exposed to 5 mg L-1 of PLA-MPs declined to 52.4 %, signifying a higher rate of mortality when contrasted with PET-MPs, which exhibited 85.7 % survival rate. Chronic exposure to 1 and 5 mgL-1 PLA-MPs resulted in a decrease of offspring, while increasing the sex ratio and deformed embryo. Interestingly, down-regulation of the SOD and AK genes was observed in...
Source: Aquatic Toxicology - December 9, 2023 Category: Toxicology Authors: Gersan An Joorim Na Jinyoung Song Jinho Jung Source Type: research
Developmental toxicity and neurobehavioral effects of sodium selenite and selenium nanoparticles on zebrafish embryos
Aquat Toxicol. 2023 Dec 5;266:106791. doi: 10.1016/j.aquatox.2023.106791. Online ahead of print.ABSTRACTSelenium, a trace mineral, is essential for several physiological processes in humans and animals. It is an antioxidant vital for the immunological response, DNA synthesis, thyroid hormone metabolism, and antioxidant defense enzymes. Zebrafish embryos and larvae were exposed to different concentrations of sodium selenite (SodSe) and selenium nanoparticles (SeNs) at various developmental stages. The study evaluated the impact of SodSe and SeNs on larvae survival, hatching rate, and morphological abnormalities. Also, acrid...
Source: Aquatic Toxicology - December 9, 2023 Category: Toxicology Authors: Sneha Hariharan Smarika Chauhan Eswar Marcharla Carlton Ranjith Wilson Alphonse Rajesh Kannan Rajaretinam Swamynathan Ganesan Source Type: research
Toxic effects of environmentally relevant concentrations of naproxen exposure on Daphnia magna including antioxidant system, development, and reproduction
Aquat Toxicol. 2023 Dec 7;266:106794. doi: 10.1016/j.aquatox.2023.106794. Online ahead of print.ABSTRACTNaproxen (NPX) is one of common non-prescription non-steroidal anti-inflammatory drugs (NSAIDs) which is widely detected in aquatic environments worldwide due to its high usage and low degradation. NPX exerts anti-inflammatory and analgesic pharmacological effects through the inhibition of prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase (COX). Given its evolutionarily relatively conserved biological functions, the potential toxic effects of NPX on non-target aquatic organisms deserve more attenti...
Source: Aquatic Toxicology - December 8, 2023 Category: Toxicology Authors: Yufei Zhao Limei Hu Yingshi Hou Yimeng Wang Ying Peng Xiangping Nie Source Type: research
Whole genome identification of olive flounder (Paralichthys olivaceus) cathepsin genes: Provides insights into its regulation on biotic and abiotic stresses response
Aquat Toxicol. 2023 Dec 3;266:106783. doi: 10.1016/j.aquatox.2023.106783. Online ahead of print.ABSTRACTCathepsins are major lysosomal enzymes involved in essential physiological processes, including protein degradation, tissue differentiation, and innate or adaptive responses. Several kinds of cathepsins have been reported in teleost fishes, but no characterization have been performed for the inflammatory response of cathepsin family in olive flounder until now. In our current study, a total of 17 cathepsins in olive flounder were systematically identified and characterized. Phylogenetic analysis clearly indicated that th...
Source: Aquatic Toxicology - December 8, 2023 Category: Toxicology Authors: Qingping Xie Tingyan Yao Xuanyang Sun Xiumei Liu Xubo Wang Source Type: research
Toxic effects of environmentally relevant concentrations of naproxen exposure on Daphnia magna including antioxidant system, development, and reproduction
Aquat Toxicol. 2023 Dec 7;266:106794. doi: 10.1016/j.aquatox.2023.106794. Online ahead of print.ABSTRACTNaproxen (NPX) is one of common non-prescription non-steroidal anti-inflammatory drugs (NSAIDs) which is widely detected in aquatic environments worldwide due to its high usage and low degradation. NPX exerts anti-inflammatory and analgesic pharmacological effects through the inhibition of prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase (COX). Given its evolutionarily relatively conserved biological functions, the potential toxic effects of NPX on non-target aquatic organisms deserve more attenti...
Source: Aquatic Toxicology - December 8, 2023 Category: Toxicology Authors: Yufei Zhao Limei Hu Yingshi Hou Yimeng Wang Ying Peng Xiangping Nie Source Type: research
Whole genome identification of olive flounder (Paralichthys olivaceus) cathepsin genes: Provides insights into its regulation on biotic and abiotic stresses response
Aquat Toxicol. 2023 Dec 3;266:106783. doi: 10.1016/j.aquatox.2023.106783. Online ahead of print.ABSTRACTCathepsins are major lysosomal enzymes involved in essential physiological processes, including protein degradation, tissue differentiation, and innate or adaptive responses. Several kinds of cathepsins have been reported in teleost fishes, but no characterization have been performed for the inflammatory response of cathepsin family in olive flounder until now. In our current study, a total of 17 cathepsins in olive flounder were systematically identified and characterized. Phylogenetic analysis clearly indicated that th...
Source: Aquatic Toxicology - December 8, 2023 Category: Toxicology Authors: Qingping Xie Tingyan Yao Xuanyang Sun Xiumei Liu Xubo Wang Source Type: research
Triclosan exposure induces immunotoxic impacts by disrupting the immunometabolism, detoxification, and cellular homeostasis in blood clam (Tegillarca granosa)
Aquat Toxicol. 2023 Nov 24;266:106778. doi: 10.1016/j.aquatox.2023.106778. Online ahead of print.ABSTRACTOmnipresent presence of triclosan (TCS) in aqueous environment puts a potential threat to organisms. However, it's poorly understood about its immunometabolic impacts of marine invertebrates. In present study, we use a representative bivalve blood clam (Tegillarca granosa) as a model, investigating the effects of TCS exposure at 20 and 200 μg/L for 28 days on immunometabolism, detoxification, and cellular homeostasis to explore feasible toxicity mechanisms. Results demonstrated that the clams exposed to TCS resulting i...
Source: Aquatic Toxicology - December 6, 2023 Category: Toxicology Authors: Yu Han Weixia Zhang Yu Tang Wei Shi Zhiquan Liu Imane Lamine Hangjun Zhang Jing Liu Guangxu Liu Source Type: research
Triclosan exposure induces immunotoxic impacts by disrupting the immunometabolism, detoxification, and cellular homeostasis in blood clam (Tegillarca granosa)
Aquat Toxicol. 2023 Nov 24;266:106778. doi: 10.1016/j.aquatox.2023.106778. Online ahead of print.ABSTRACTOmnipresent presence of triclosan (TCS) in aqueous environment puts a potential threat to organisms. However, it's poorly understood about its immunometabolic impacts of marine invertebrates. In present study, we use a representative bivalve blood clam (Tegillarca granosa) as a model, investigating the effects of TCS exposure at 20 and 200 μg/L for 28 days on immunometabolism, detoxification, and cellular homeostasis to explore feasible toxicity mechanisms. Results demonstrated that the clams exposed to TCS resulting i...
Source: Aquatic Toxicology - December 6, 2023 Category: Toxicology Authors: Yu Han Weixia Zhang Yu Tang Wei Shi Zhiquan Liu Imane Lamine Hangjun Zhang Jing Liu Guangxu Liu Source Type: research
Effects of dissolved organic matter, pH and nutrient on ciprofloxacin bioaccumulation and toxicity in duckweed
This study focused on exploring ciprofloxacin (CIP) removal by duckweed and assessing CIP bioaccumulation and toxic effects within duckweed under varying dissolved organic matter categories, pH levels, and nutrient (nitrogen (N) and phosphorus (P)) levels. The results revealed the proficient and rapid elimination of CIP from water by duckweed, resulting in 86.17 % to 92.82 % removal efficiency at the end of the 7-day experiment. Across all exposure groups, varying degrees of CIP bioaccumulation in duckweed were evident, with uptake established as a primary pathway for CIP elimination within this plant. Additionally, five C...
Source: Aquatic Toxicology - December 3, 2023 Category: Toxicology Authors: Mengnan Shen Yi Hu Ke Zhao Zhi Qu Chen Lyu Binshuo Liu Ming Li Xiaodan Bu Chenyang Li Shuang Zhong Jie Cheng Source Type: research
