Capillary refill time response to a fluid challenge or a vasopressor test: an observational, proof-of-concept study
Several studies have validated capillary refill time (CRT) as a marker of tissue hypoperfusion, and recent guidelines recommend CRT monitoring during septic shock resuscitation. Therefore, it is relevant to fu... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - April 1, 2024 Category: Intensive Care Authors: Glenn Hern ández, Emilio Daniel Valenzuela, Eduardo Kattan, Ricardo Castro, Camila Guzmán, Alicia Elzo Kraemer, Nicolás Sarzosa, Leyla Alegría, Roberto Contreras, Vanessa Oviedo, Sebastián Bravo, Dagoberto Soto, Claudia Sáez, Hafid Ait-Oufella, Gust Tags: Research Source Type: research

The association of premorbid conditions with 6-month mortality in acutely admitted ICU patients over 80 years
Premorbid conditions influence the outcome of acutely ill adult patients aged 80 years and over who are admitted to the ICU. The aim of this study was to determine the influence of such premorbid conditions on... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 30, 2024 Category: Intensive Care Authors: Dylan W. de Lange, Ivo W. Soliman, Susannah Leaver, Ariane Boumendil, Lenneke E. M. Haas, Ximena Watson, Carol Boulanger, Wojciech Szczeklik, Antonio Artigas, Alessandro Morandi, Finn Andersen, Christian Jung, Rui Moreno, Sten Walther, Sandra Oeyen, Joerg Tags: Research Source Type: research

Management of cardiogenic shock: a narrative review
Cardiogenic shock (CS) is characterized by low cardiac output and sustained tissue hypoperfusion that may result in end-organ dysfunction and death. CS is associated with high short-term mortality, and its man... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 30, 2024 Category: Intensive Care Authors: Driss Laghlam, Sarah Benghanem, Sofia Ortuno, Nadia Bouabdallaoui, Stephane Manzo-Silberman, Olfa Hamzaoui and Nadia Aissaoui Tags: Review Source Type: research

Clinical description and outcome of overall varicella-zoster virus-related organ dysfunctions admitted in intensive care units: the VAZOREA cohort study
Due to aging population and increasing part of immunocompromised patients, a raise in life-threatening organ damage related to VZV can be expected. Two retrospective studies were already conducted on VZV in IC... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 29, 2024 Category: Intensive Care Authors: Jolan Malherbe, Pierre Godard, Jean-Claude Lacherade, Valentin Coirier, Laurent Argaud, Herv é Hyvernat, Francis Schneider, Julien Charpentier, Florent Wallet, Juliette Pocquet, Gaëtan Plantefeve, Jean-Pierre Quenot, Pierre Bay, Agathe Delbove, Hugues G Tags: Research Source Type: research

Early sevoflurane sedation in severe COVID-19-related lung injury patients. A pilot randomized controlled trial
This study aimed to assess a potential organ protective effect of volatile sedation in a scenario of severe inflammation with an early cytokine storm (in particular IL-6 elevation) in patients suffering from C... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 27, 2024 Category: Intensive Care Authors: Beatrice Beck-Schimmer, Erik Schadde, Urs Pietsch, Miodrag Filipovic, Seraina D übendorfer-Dalbert, Patricia Fodor, Tobias Hübner, Reto Schuepbach, Peter Steiger, Sascha David, Bernard D. Krüger, Thomas A. Neff and Martin Schläpfer Tags: Research Source Type: research

Gut barrier dysfunction and the risk of ICU-acquired bacteremia- a case –control study
Impaired intestinal barrier function can enable passage of enteric microorganisms into the bloodstream and lead to nosocomial bloodstream infections during critical illness. We aimed to determine the relative ... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 27, 2024 Category: Intensive Care Authors: Meri R. J. Varkila, Diana M. Verboom, Lennie P. G. Derde, Tom van der Poll, Marc J. M. Bonten and Olaf L. Cremer Tags: Research Source Type: research

Serial daily lactate levels association with 30-day outcome in cardiogenic shock patients treated with VA-ECMO: a post-hoc analysis of the HYPO-ECMO study
Reliable predictors of outcomes in venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy are limited. While elevated lactate levels over time have been linked to outcomes in cardiogenic shock (CS)... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 27, 2024 Category: Intensive Care Authors: Bruno Levy, Nicolas Girerd, Guillaume Baudry, Kevin Duarte, Samuel Cuau, Jan Bakker and Antoine Kimmoun Tags: Research Source Type: research

Right ventricular injury in patients with COVID-19-related ARDS eligible for ECMO support: a multicenter retrospective study
Coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS) is associated with high mortality. Extracorporeal membrane oxygenation (ECMO) has been proposed in this setting, but optim... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 26, 2024 Category: Intensive Care Authors: Matthieu Petit, Misylias Bouaoud, Edouard Jullien, Adrien Joseph, Bruno Evrard, Cyril Charron, Anousone Daulasim, Annick Legras, Maeva Gourraud, Marine Goudelin, Philippe Vignon and Antoine Vieillard-Baron Tags: Research Source Type: research

Assessment of COVID-19-related right ventricular morphological and functional alterations and evaluation of their impact on the course of the disease
(Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 26, 2024 Category: Intensive Care Authors: Michael Dandel Tags: Letter to the Editor Source Type: research

Diaphragm thickness modifications and associated factors during VA-ECMO for a cardiogenic shock: a cohort study
The incidence, causes and impact of diaphragm thickness evolution in veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock are unknown. (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 8, 2024 Category: Intensive Care Authors: Pierre-Henri Moury, Alexandre B éhouche, Sébastien Bailly, Zoé Durand, Géraldine Dessertaine, Angelina Pollet, Samir Jaber, Samuel Verges and Pierre Albaladejo Tags: Research Source Type: research

Letter on “Bioimpedance-assessed muscle wasting and its relation to nutritional intake during the first week of ICU: a pre-planned secondary analysis of Nutriti Study”
(Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 7, 2024 Category: Intensive Care Authors: Libing Jiang and Shanxiang Xu Tags: Letter to the Editor Source Type: research

Association between pupillary examinations and prognosis in patients with out-of-hospital cardiac arrest who underwent extracorporeal cardiopulmonary resuscitation: a retrospective multicentre cohort study
In some cases of patients with out-of-hospital cardiac arrest (OHCA) who underwent extracorporeal cardiopulmonary resuscitation (ECPR), negative pupillary light reflex (PLR) and mydriasis upon hospital arrival... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 6, 2024 Category: Intensive Care Authors: Takuro Hamaguchi, Toru Takiguchi, Tomohisa Seki, Naoki Tominaga, Jun Nakata, Takeshi Yamamoto, Takashi Tagami, Akihiko Inoue, Toru Hifumi, Tetsuya Sakamoto, Yasuhiro Kuroda, Shoji Yokobori and the SAVE-J II study group Tags: Research Source Type: research

Impact of a multidisciplinary management team on clinical outcome in ICU patients affected by Gram-negative bloodstream infections: a pre-post quasi-experimental study
Bloodstream infections (BSIs) by Gram-negative pathogens play a major role in intensive care patients, both in terms of prevalence and severity, especially if multi-drug resistant pathogens are involved. Early... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 6, 2024 Category: Intensive Care Authors: Matteo Rinaldi, Milo Gatti, Tommaso Tonetti, Domenico Nocera, Simone Ambretti, Andrea Berlingeri, Giacomo Nigrisoli, Elisabetta Pierucci, Antonio Siniscalchi, Federico Pea, Pierluigi Viale and Maddalena Giannella Tags: Research Source Type: research

Covid-19-associated pulmonary aspergillosis in mechanically ventilated patients
(Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 1, 2024 Category: Intensive Care Authors: Guangting Zeng and Linlin Wang Tags: Letter to the Editor Source Type: research

Immediate vs. culture-initiated antibiotic therapy in suspected non-severe ventilator-associated pneumonia: a before –after study (DELAVAP)
Ventilator-associated pneumonia (VAP) is the leading nosocomial infection in critical care and is associated with adverse outcomes. When VAP is suspected, starting antibiotic therapy (AT) immediately after pul... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - February 27, 2024 Category: Intensive Care Authors: Ma ëlle Martin, Solène Forveille, Jean-Baptiste Lascarrou, Amélie Seguin, Emmanuel Canet, Jérémie Lemarié, Maïté Agbakou, Luc Desmedt, Gauthier Blonz, Olivier Zambon, Stéphane Corvec, Aurélie Le Thuaut and Jean Reignier Tags: Research Source Type: research