Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study —an ancillary study of a randomized controlled trial
Sepsis prognosis correlates with antibiotic adequacy at the early phase. This adequacy is dependent on antibacterial spectrum, bacterial resistance profile and antibiotic dosage. Optimal efficacy of beta-lacta... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - February 25, 2023 Category: Intensive Care Authors: Damien Roux, Nicolas Benichou, David Hajage, Laurent Martin-Lef èvre, Nicolas de Prost, Nicolas Lerolle, Dimitri Titeca-Beauport, Eric Boulet, Julien Mayaux, Bruno Mégarbane, Khaoula Mahjoub, Dorothée Carpentier, Saad Nseir, Florence Tubach, Jean-Damie Tags: Research Source Type: research
Electroencephalography for prognostication of outcome in adults with severe herpes simplex encephalitis
Electroencephalography (EEG) is recommended for the practical approach to the diagnosis and prognosis of encephalitis. We aimed to investigate the prognostic value of standard EEG (stdEEG) in adult patients with ... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - February 23, 2023 Category: Intensive Care Authors: Lina Jeantin, Claire Dupuis, Geoffroy Vellieux, Pierre Jaquet, Etienne de Montmollin, Jean-Fran çois Timsit and Romain Sonneville Tags: Research Source Type: research
Association of systolic, diastolic, mean, and pulse pressure with morbidity and mortality in septic ICU patients: a nationwide observational study
Intensivists target different blood pressure component values to manage intensive care unit (ICU) patients with sepsis. We aimed to evaluate the relationship between individual blood pressure components and or... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - February 20, 2023 Category: Intensive Care Authors: Ashish K. Khanna, Takahiro Kinoshita, Annamalai Natarajan, Emma Schwager, Dustin D. Linn, Junzi Dong, Erina Ghosh, Francesco Vicario and Kamal Maheshwari Tags: Research Source Type: research
Critically ill patient mortality by age: long-term follow-up (CIMbA-LT)
The past years have witnessed dramatic changes in the population admitted to the intensive care unit (ICU). Older and sicker patients are now commonly treated in this setting due to the newly available sophist... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - February 11, 2023 Category: Intensive Care Authors: Jo ão Gonçalves-Pereira, André Oliveira, Tatiana Vieira, Ana Rita Rodrigues, Maria João Pinto, Sara Pipa, Ana Martinho, Sofia Ribeiro and José-Artur Paiva Tags: Research Source Type: research
Outcomes in participants with ventilated nosocomial pneumonia and organ failure treated with ceftolozane/tazobactam versus meropenem: a subset analysis of the phase 3, randomized, controlled ASPECT-NP trial
The pivotal ASPECT-NP trial showed ceftolozane/tazobactam was non-inferior to meropenem for the treatment of ventilated hospital-acquired/ventilator-associated bacterial pneumonia (vHABP/VABP). Here, we evalua... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - February 11, 2023 Category: Intensive Care Authors: Ignacio Martin-Loeches, Andrew F. Shorr, Richard G. Wunderink, Marin H. Kollef, Jean-Fran çois Timsit, Brian Yu, Jennifer A. Huntington, Erin Jensen and Christopher J. Bruno Tags: Research Source Type: research
ICU patients with infectious complications after abdominopelvic surgery: Is thoracic CT in addition to abdominal CT helpful?
The aim of this study was to assess the usefulness of adding thoracic CT to abdominal CT in intensive care unit (ICU) patients with signs of infection after abdominopelvic surgery. (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - February 10, 2023 Category: Intensive Care Authors: Heiner Nebelung, Natalie Wotschel, Hanns-Christoph Held, Johanna Kirchberg, J ürgen Weitz, Christoph Georg Radosa, Michael Laniado, Ralf-Thorsten Hoffmann and Verena Plodeck Tags: Research Source Type: research
Development and validation of a multivariable model predicting the required catheter dwell time among mechanically ventilated critically ill patients in three randomized trials
The anatomic site for central venous catheter insertion influences the risk of central venous catheter-related intravascular complications. We developed and validated a predictive score of required catheter dw... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - January 16, 2023 Category: Intensive Care Authors: Jeanne Iachkine, Niccol ò Buetti, Harm-Jan de Grooth, Anaïs R. Briant, Olivier Mimoz, Bruno Mégarbane, Jean-Paul Mira, Xavier Valette, Cédric Daubin, Damien du Cheyron, Leonard A. Mermel, Jean-François Timsit and Jean-Jacques Parienti Tags: Research Source Type: research
Trained intensivist coverage and survival outcomes in critically ill patients: a nationwide cohort study in South Korea
The difference in survival outcomes between closed and open intensive care unit (ICU) designs with respect to trained intensivist coverage remains unknown. We aimed to investigate whether trained intensivist c... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - January 13, 2023 Category: Intensive Care Authors: Tak Kyu Oh and In-Ae Song Tags: Research Source Type: research
The prevalence of sepsis-induced coagulopathy in patients with sepsis – a secondary analysis of two German multicenter randomized controlled trials
Sepsis and septic shock are frequently accompanied by coagulopathy. Since the sepsis-induced coagulopathy (SIC) score was first described, subsequent studies from Asia revealed a SIC prevalence of 40 –60%. In E... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - January 12, 2023 Category: Intensive Care Authors: Thomas Schmoch, Patrick M öhnle, Markus A. Weigand, Josef Briegel, Michael Bauer, Frank Bloos, Patrick Meybohm, Didier Keh, Markus Löffler, Gunnar Elke, Thorsten Brenner and Holger Bogatsch Tags: Research Source Type: research
Trends in clinical characteristics and outcomes of all critically ill COVID-19 adult patients hospitalized in France between March 2020 and June 2021: a national database study
Studies regarding coronavirus disease 2019 (COVID-19) were mainly performed in the initial wave, but some small-scale data points to prognostic differences for patients in successive waves. We therefore aimed ... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - January 12, 2023 Category: Intensive Care Authors: Diane Naouri, Albert Vuagnat, Ga ëtan Beduneau, Martin Dres, Tai Pham, Alain Mercat, Alain Combes, Alexandre Demoule, Antoine Kimmoun, Matthieu Schmidt and Matthieu Jamme Tags: Research Source Type: research
Role of nebulized colistin as a substitutive strategy against nosocomial pneumonia caused by CR-GNB in intensive care units: a retrospective cohort study
Adverse reactions, especially nephrotoxicity, are great concerns of intravenous colistin treatment. The role of substitutive nebulized colistin in treating nosocomial pneumonia caused by carbapenem-resistant G... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - January 7, 2023 Category: Intensive Care Authors: Jia-Yih Feng, Jhong-Ru Huang, Chang-Ching Lee, Yen-Han Tseng, Sheng-Wei Pan, Yuh-Min Chen and Kuang-Yao Yang Tags: Research Source Type: research
Frailty is a stronger predictor of death in younger intensive care patients than in older patients: a prospective observational study
While frailty is a known predictor of adverse outcomes in older patients, its effect in younger populations is unknown. This prospective observational study was conducted in a tertiary-level mixed ICU to asses... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - December 31, 2022 Category: Intensive Care Authors: Lina De Geer, Mats Fredrikson and Michelle S. Chew Tags: Research Source Type: research
Auto-antibodies against type I IFNs in > 10% of critically ill COVID-19 patients: a prospective multicentre study
Auto-antibodies (auto-Abs) neutralizing type I interferons (IFN) have been found in about 15% of critical cases COVID-19 pneumonia and less than 1% of mild or asymptomatic cases. Determining whether auto-Abs i... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - December 31, 2022 Category: Intensive Care Authors: Romain Arrestier, Paul Bastard, Thibaut Belmondo, Guillaume Voiriot, Tomas Urbina, Charles-Edouard Luyt, Adrian Gervais, Lucy Bizien, Lauriane Segaux, Mariem Ben Ahmed, Rapha ël Bellaïche, Taï Pham, Zakaria Ait-Hamou, Damien Roux, Raphael Clere-Jehl, E Tags: Research Source Type: research
Cerebrovascular complications and outcomes of critically ill adult patients with infective endocarditis
Neurological complications are associated with poor outcome in patients with infective endocarditis (IE). Although guidelines recommend systematic brain imaging in the evaluation of IE patients, the associatio... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - December 30, 2022 Category: Intensive Care Authors: Thomas Rambaud, Etienne de Montmollin, Pierre Jaquet, Augustin Gaudemer, Eric Mariotte, Sonia Abid, Marylou Para, Claire Cimadevilla, Bernard Iung, Xavier Duval, Michel Wolff, Lila Bouadma, Jean-Fran çois Timsit and Romain Sonneville Tags: Research Source Type: research
Changing epidemiology of acute kidney injury in critically ill patients with COVID-19: a prospective cohort
Acute kidney injury (AKI) is common in critically ill patients with coronavirus disease-19 (COVID-19). We aimed to explore the changes in AKI epidemiology between the first and the second COVID wave in the Uni... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - December 28, 2022 Category: Intensive Care Authors: Nuttha Lumlertgul, Eleanor Baker, Emma Pearson, Kathryn V. Dalrymple, Jacqueline Pan, Anup Jheeta, Kittisak Weerapolchai, Yanzhong Wang, Richard Leach, Nicholas A. Barrett and Marlies Ostermann Tags: Research Source Type: research
