ICU admission for solid cancer patients treated with immune checkpoint inhibitors
Immune checkpoint inhibitors (ICI) have revolutionized the management of cancer. They can induce immune-related adverse events (irAE) leading to intensive care unit (ICU) admission. We aimed to describe irAEs ... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - April 18, 2023 Category: Intensive Care Authors: Anne-Claire Toffart, Anne-Pascale Meert, Florent Wallet, Aude Gibelin, Olivier Guisset, Fr édéric Gonzalez, Amélie Seguin, Achille Kouatchet, Myriam Delaunay, Didier Debieuvre, Boris Duchemann, Gaëlle Rousseau-Bussac, Martine Nyunga, David Grimaldi, A Tags: Research Source Type: research
The positive impact of COVID-19 on critical care: from unprecedented challenges to transformative changes, from the perspective of young intensivists
Over the past 2 years, SARS-CoV-2 infection has resulted in numerous hospitalizations and deaths worldwide. As young intensivists, we have been at the forefront of the fight against the COVID-19 pandemic and i... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - April 11, 2023 Category: Intensive Care Authors: Bertrand Hermann, Sarah Benghanem, Youenn Jouan, Antoine Lafarge and Alexandra Beurton Tags: Review Source Type: research
Multiple-site decontamination to prevent acquired infection in patients with veno-venous ECMO support
Acute distress respiratory syndrome (ARDS) patients with veno-venous extra corporeal membrane oxygenation (ECMO) support are particularly exposed to ECMO-associated infection (ECMO-AI). Unfortunately, data reg... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - April 7, 2023 Category: Intensive Care Authors: Nicolas Massart, Christophe Camus, Nicolas Nesseler, Pierre Fill âtre, Erwan Flecher, Alexandre Mansour, Jean-Philippe Verhoye, Lucie Le Fevre and Charles-Edouard Luyt Tags: Research Source Type: research
Bridging gut microbiota composition with extended-spectrum beta-lactamase Enterobacteriales faecal carriage in critically ill patients (microbe cohort study)
The worldwide dissemination of extended spectrum beta-lactamase producing Enterobacteriales (ESBL-E) is of major concern. Microbiota may play a role in the host resistance to colonization with ESBL-E, but the und... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - April 4, 2023 Category: Intensive Care Authors: Renaud Prevel, Rapha ël Enaud, Arthur Orieux, Adrian Camino, Pierre Sioniac, Fatima M’Zali, Véronique Dubois, Patrick Berger, Alexandre Boyer, Laurence Delhaes and Didier Gruson Tags: Research Source Type: research
Preoxygenation with standard facemask combining apnoeic oxygenation using high flow nasal cannula versuss standard facemask alone in patients with and without obesity: the OPTIMASK international study
Combining oxygen facemask with apnoeic oxygenation using high-flow-nasal-oxygen (HFNO) for preoxygenation in the operating room has not been studied against standard oxygen facemask alone. We hypothesized that... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - April 4, 2023 Category: Intensive Care Authors: Samir Jaber, Audrey De Jong, Maximilian S. Schaefer, Jiaqiang Zhang, Xiaowen Ma, Xinrui Hao, Shujing Zhou, Shang Lv, Valerie Banner-Goodspeed, Xiuhua Niu, Thomas Sfara and Daniel Talmor Tags: Research Source Type: research
Differences in clinical characteristics and quantitative lung CT features between vaccinated and not vaccinated hospitalized COVID-19 patients in Italy
To evaluate the differences in the clinical characteristics and severity of lung impairment, assessed by quantitative lung CT scan, between vaccinated and non-vaccinated hospitalized patients with COVID-19; an... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - April 3, 2023 Category: Intensive Care Authors: Davide Chiumello, Alessandro Tavelli, Lorenzo Serio, Sara De Benedittis, Tommaso Pozzi, Roberta Maj, Mara Velati, Serena Brusatori, Rosanna D ’Albo, Carmelo Zinnato, Giulia Marchetti, Luigi Camporota, Silvia Coppola and Antonella D’Arminio Monforte Tags: Research Source Type: research
The outcome of acute kidney injury substages based on urinary cystatin C in critically ill children
The concept of acute kidney injury (AKI) substages has been recommended to better phenotype AKI and identify high-risk patient groups and therefore improve the diagnostic accuracy of AKI. However, there remain... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 28, 2023 Category: Intensive Care Authors: Jiao Chen, Zhen Jiang, Hui Huang, Min Li, Zhenjiang Bai, Yuxian Kuai, Lin Wei, Ning Liu, Xiaozhong Li, Guoping Lu and Yanhong Li Tags: Research Source Type: research
Efficacy of carbapenem vs non carbapenem β-lactam therapy as empiric antimicrobial therapy in patients with extended-spectrum β-lactamase-producing Enterobacterales urinary septic shock: a propensity-weighted multicenter cohort study
The rise in antimicrobial resistance is a global threat responsible for about 33,000 deaths in 2015 with a particular concern for extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) and has led t... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 24, 2023 Category: Intensive Care Authors: Erwann Cariou, Romain Griffier, Arthur Orieux, Stein Silva, Stanislas Faguer, Thierry Seguin, Saad Nseir, Emmanuel Canet, Arnaud Desclaux, Bertrand Souweine, Kada Klouche, Olivier Guisset, Jerome Pillot, Walter Picard, Tahar Saghi, Pierre Delobel & hellip Tags: Research Source Type: research
Clinical significance of human metapneumovirus detection in critically ill adults with lower respiratory tract infections
Unlike other viruses, the pathogenicity of human metapneumovirus (hMPV) in adults remains uncertain. To address this question, a retrospective monocentric cohort including all patients admitted to ICU with hMP... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 20, 2023 Category: Intensive Care Authors: Natacha Kapandji, Michael Darmon, Sandrine Valade, Maud Salmona, J érôme Legoff, Lara Zafrani, Elie Azoulay and Virginie Lemiale Tags: Research Source Type: research
Correction: Trends in clinical characteristics and outcomes of all critically ill COVID-19 adult patients hospitalized in France between March 2020 and June 2021: a national database study
(Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 19, 2023 Category: Intensive Care Authors: Diane Naouri, Albert Vuagnat, Ga ëtan Beduneau, Martin Dres, Tai Pham, Alain Mercat, Alain Combes, Alexandre Demoule, Antoine Kimmoun, Matthieu Schmidt and Matthieu Jamme Tags: Correction Source Type: research
ICU health care workers opinion on physician-assisted-suicide and euthanasia: a French survey
In France, physician-assisted suicide or euthanasia are not legal but are still debated. French intensive care unit (ICU) health care workers (HCWs) have an insider ’s perspective on the global quality of the p... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 18, 2023 Category: Intensive Care Authors: Mathieu Acquier, Alexandre Boyer, Bertrand Guidet, Alexandre Lautrette, Jean Reignier, Guillaume Thiery and Ren é Robert Tags: Research Source Type: research
Long-term outcomes after severe acute kidney injury in critically ill patients: the SALTO study
The extent of the consequences of an episode of severe acute kidney injury (AKI) on long-term outcome of critically ill patients remain debated. We conducted a prospective follow-up of patients included in a l... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 13, 2023 Category: Intensive Care Authors: Khalil Cha ïbi, Franck Ehooman, Bertrand Pons, Laurent Martin-Lefevre, Eric Boulet, Alexandre Boyer, Guillaume Chevrel, Nicolas Lerolle, Dorothée Carpentier, Nicolas de Prost, Alexandre Lautrette, Anne Bretagnol, Julien Mayaux, Saad Nseir, Bruno Megarba Tags: Research Source Type: research
Intravenously administered interleukin-7 to reverse lymphopenia in patients with septic shock: a double-blind, randomized, placebo-controlled trial
Profound lymphopenia is an independent predictor of adverse clinical outcomes in sepsis. Interleukin-7 (IL-7) is essential for lymphocyte proliferation and survival. A previous phase II study showed that CYT10... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 12, 2023 Category: Intensive Care Authors: Thomas Daix, Armelle Mathonnet, Scott Brakenridge, Pierre-Fran çois Dequin, Jean-Paul Mira, Frederique Berbille, Michel Morre, Robin Jeannet, Teresa Blood, Jacqueline Unsinger, Jane Blood, Andrew Walton, Lyle L. Moldawer, Richard Hotchkiss and Bruno Fran Tags: Research Source Type: research
Unapparent systemic effects of regional anticoagulation with citrate in continuous renal replacement therapy: a narrative review
The use of citrate, through reversible binding of calcium, has become the preferred choice for anticoagulation in continuous renal replacement therapy in the critically ill patient. Though generally considered... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 11, 2023 Category: Intensive Care Authors: Willem Boer, Walter Verbrugghe, Eric Hoste, Rita Jacobs and Philippe G. Jorens Tags: Review Source Type: research
Critically ill severe hypothyroidism: a retrospective multicenter cohort study
Severe hypothyroidism (SH) is a rare but life-threatening endocrine emergency. Only a few data are available on its management and outcomes of the most severe forms requiring ICU admission. We aimed to describ... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - March 9, 2023 Category: Intensive Care Authors: Simon Bourcier, Maxime Coutrot, Alexis Ferr é, Nicolas Van Grunderbeeck, Julien Charpentier, Sami Hraiech, Elie Azoulay, Saad Nseir, Nadia Aissaoui, Jonathan Messika, Pierre Fillatre, Romain Persichini, Serge Carreira, Alexandre Lautrette, Clément Delma Tags: Research Source Type: research
