Women Anesthesiologists in Sub-Saharan Africa in the Pre-COVID Era: A Multinational Demographic Study
CONCLUSIONS: On average, in SSA, female medical graduates (36.9%), female anesthesiologists (24.9%), and female anesthesiology residents projected to graduate between 2018 and 2022 (25.2%) were underrepresented when compared to their male counterparts. Women were underrepresented in SSA, despite evidence that their representation in medicine and anesthesiology in East African countries was rising.PMID:38300845 | DOI:10.1213/ANE.0000000000006868 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - February 1, 2024 Category: Anesthesiology Authors: Bertille K Ki Bisola Onajin-Obembe Oyebola Adekola Philippe L Baele Fidele Binam Hadjara Daddy Elizabeth Diouf Lionelle Fanou Zipporah N Gathuya Elizabeth N Igaga Emilia Jeque Peggy Mawandza Mary T Nabukenya Susane M Nabulindo R C Nicole Rakotoarison Anni Source Type: research

High Neuraxial Block in Obstetrics: A 2.5-Year Nationwide Surveillance Approach in the Netherlands
CONCLUSIONS: High neuraxial block requiring tracheal intubation is a rare but impactful complication in obstetric anesthesia, potentially affecting both mother and fetus. Spinal anesthesia after epidural analgesia in labor is a common cause of high neuraxial block. Meticulous follow-up of epidurals in labor facilitates conversion to surgical anesthesia and may therefore reduce the need for spinal anesthesia after epidural analgesia. Large-scale surveillance systems in obstetric anesthesia are needed to identify those at risk, as well as to formulate further strategies to mitigate this burden.PMID:38294948 | DOI:10.1213/ANE...
Source: Anesthesia and Analgesia - January 31, 2024 Category: Anesthesiology Authors: Ingrid C M Beenakkers Timme P Schaap Oscar F C van den Bosch Source Type: research

Analgesic Effect of Exercise on Neuropathic Pain via Regulating the Complement Component 3 of Reactive Astrocytes
CONCLUSIONS: Overall, these results suggest that exercise suppresses neuropathic pain by regulating astroglial C3 expression and function, thereby providing a rationale for the analgesic effect of exercise as an acceptable alternative approach for treating neuropathic pain.PMID:38294950 | DOI:10.1213/ANE.0000000000006884 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - January 31, 2024 Category: Anesthesiology Authors: Chenghao Wang Hui He Tianchi Gao Xinzheng Sun Lixia Du Yayue Yang Jianyu Zhu Yachen Yang Yanqing Wang Wenli Mi Source Type: research

The Association of Guideline-Directed Prophylaxis With Postoperative Nausea and Vomiting in Adult Patients: A Single-Center, Retrospective Cohort Study
CONCLUSIONS: Guideline-directed PONV prophylaxis is associated with a modest reduction in PONV, although this effect is small and heterogeneous on the absolute scale. We found evidence for a differential association between adequate prophylaxis and PONV across the guideline-defined risk spectrum, with diminution in patients at very high predicted preoperative risk. While patient-specific benefit was heterogenous, most patients had reasonably high predicted probabilities of absolute benefit from a guideline-directed strategy. Further assessment of these associations in a multicenter setting, with more robust investigation o...
Source: Anesthesia and Analgesia - January 31, 2024 Category: Anesthesiology Authors: Benjamin Y Andrew Romel Holmes Brad M Taicher Ashraf S Habib Source Type: research

Esketamine: Less Drowsiness, More Analgesia
Anesth Analg. 2024 Jan 31. doi: 10.1213/ANE.0000000000006851. Online ahead of print.ABSTRACTRacemic ketamine is a 1:1 mixture of 2 enantiomers that turn light in opposite direction: Dextrorotatory esketamine is approximately 4 times more affine for the N-methyl-D-aspartate (NMDA) receptor than levorotatory arketamine, which may explain why esketamine is about twice as potent as an analgesic and anesthetic as the racemate. Esketamine has attracted renewed interest in view of the opioid crisis, racemic ketamine's abuse, and esketamine's approval for expanded use. We evaluated the anesthesia literature concerning mental, card...
Source: Anesthesia and Analgesia - January 31, 2024 Category: Anesthesiology Authors: Georges Mion Sabine Himmelseher Source Type: research