Solifenacin Treatment After Intradetrusor Injections With Botulinum Toxin in Patients With Neurogenic Detrusor Overactivity
Conclusions:
Our study shows that adding solifenacin improves patient satisfaction, increases the interval between reinjections, thus lowering costs, and improves maximum bladder capacity. Pdet was kept in safe ranges, but no statistically significant conclusions could be drawn regarding Pdet and PVR decrease related to adding solifenacin. Although our study is limited by the small series of patients and lack of randomization and placebo control group, the BoNT–solifenacin combination could be considered in NDO in terms of cost-effectiveness. Further studies would be beneficial. (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - September 1, 2022 Category: Drugs & Pharmacology Tags: Original Investigation Source Type: research
Pharmacological Management of Inflammatory Bowel Disease: a Century of Expert Opinions in Cecil Textbook of Medicine
Conclusions:
The pharmacological management of IBD has been the focus of intense research and development in the past 60 years. The pillars of drug treatment have been 5-aminosalicylates and corticosteroids. Recent pharmacological innovations (immunomodulators and biologicals) constitute an encouraging paradigm shift in the treatment of UC and Crohn disease. (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - September 1, 2022 Category: Drugs & Pharmacology Tags: Original Investigation Source Type: research
Plausibility of Claimed Covid-19 Vaccine Efficacies by Age: A Simulation Study
Conclusions:
The distribution of alleged vaccine efficacies of the Sputnik vaccine by age in the phase-III trial is very unlikely to occur in genuine experimental data, even if the number of patients recruited, vaccine efficacy, and overall infection rate are true and there is no underlying difference in vaccine efficacy by age. (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - September 1, 2022 Category: Drugs & Pharmacology Tags: Original Investigation Source Type: research
Kava Kava Induced Acute Liver Failure
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
Brexpiprazole in the Treatment of Cannabis Withdrawal Psychotic Disorder
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
Malignant Hyperthermia and Cisatracurium During Severe SARS-CoV-2 Infection
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
Haloperidol Toxicity and Lipid Emulsion Treatment
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
Typical versus Atypical Antipsychotics for Acute Mania: Psychopharmacological Considerations
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
Successful Ziprasidone Treatment for Resistant Attention-Deficit/Hyperactivity Disorder and Provisional Motor Tic Disorder
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
Sertraline-Associated Immunoglobulin A Vasculitis
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
Alcoholic Ketoacidosis: Review of Current Practice and Association of Treatments to Improvement
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
Stool Osmotic Gap: An Alternative to Invasive Workup of Chronic Diarrhea Secondary to Glucagon-Like Peptide-1 Agonist Use
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
Transient Psychosis After Low-Dose Pregabalin Discontinuation
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
Amikacin Monotherapy for Peripherally Inserted Central Catheter-Related Bloodstream Infection due to Tsukamurella pulmonis
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
Tocilizumab-Associated Cecal Perforation in COVID-19 Pneumonia
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
