Adenine Nucleotide Translocases and Cellular Senescence in Idiopathic Pulmonary Fibrosis
Am J Respir Cell Mol Biol. 2023 Dec 21. doi: 10.1165/rcmb.2023-0386LE. Online ahead of print.NO ABSTRACTPMID:38128103 | DOI:10.1165/rcmb.2023-0386LE (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 21, 2023 Category: Respiratory Medicine Authors: Tetsu Kobayashi Hajime Fujimoto Corina N D'Alessandro-Gabazza Taro Yasuma Esteban C Gabazza Source Type: research

Airway Microfold Cells Emerge in the Post-Influenza Lung
Am J Respir Cell Mol Biol. 2023 Dec 21. doi: 10.1165/rcmb.2023-0351LE. Online ahead of print.NO ABSTRACTPMID:38127584 | DOI:10.1165/rcmb.2023-0351LE (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 21, 2023 Category: Respiratory Medicine Authors: Justinn Barr Le Xu Rongbo Li Jamie Verheyden Xin Sun Source Type: research

Reply to: Adenine Nucleotide Translocases and Cellular Senescence in Idiopathic Pulmonary Fibrosis
Am J Respir Cell Mol Biol. 2023 Dec 21. doi: 10.1165/rcmb.2023-0405LE. Online ahead of print.NO ABSTRACTPMID:38128102 | DOI:10.1165/rcmb.2023-0405LE (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 21, 2023 Category: Respiratory Medicine Authors: Justin Sui Corrine Kliment Source Type: research

Adenine Nucleotide Translocases and Cellular Senescence in Idiopathic Pulmonary Fibrosis
Am J Respir Cell Mol Biol. 2023 Dec 21. doi: 10.1165/rcmb.2023-0386LE. Online ahead of print.NO ABSTRACTPMID:38128103 | DOI:10.1165/rcmb.2023-0386LE (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 21, 2023 Category: Respiratory Medicine Authors: Tetsu Kobayashi Hajime Fujimoto Corina N D'Alessandro-Gabazza Taro Yasuma Esteban C Gabazza Source Type: research

Airway Microfold Cells Emerge in the Post-Influenza Lung
Am J Respir Cell Mol Biol. 2023 Dec 21. doi: 10.1165/rcmb.2023-0351LE. Online ahead of print.NO ABSTRACTPMID:38127584 | DOI:10.1165/rcmb.2023-0351LE (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 21, 2023 Category: Respiratory Medicine Authors: Justinn Barr Le Xu Rongbo Li Jamie Verheyden Xin Sun Source Type: research

Reply to: Adenine Nucleotide Translocases and Cellular Senescence in Idiopathic Pulmonary Fibrosis
Am J Respir Cell Mol Biol. 2023 Dec 21. doi: 10.1165/rcmb.2023-0405LE. Online ahead of print.NO ABSTRACTPMID:38128102 | DOI:10.1165/rcmb.2023-0405LE (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 21, 2023 Category: Respiratory Medicine Authors: Justin Sui Corrine Kliment Source Type: research

Adenine Nucleotide Translocases and Cellular Senescence in Idiopathic Pulmonary Fibrosis
Am J Respir Cell Mol Biol. 2023 Dec 21. doi: 10.1165/rcmb.2023-0386LE. Online ahead of print.NO ABSTRACTPMID:38128103 | DOI:10.1165/rcmb.2023-0386LE (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 21, 2023 Category: Respiratory Medicine Authors: Tetsu Kobayashi Hajime Fujimoto Corina N D'Alessandro-Gabazza Taro Yasuma Esteban C Gabazza Source Type: research

The Regulation of FASN by Exosomal miR-143-5p and miR-342-5p in Idiopathic Pulmonary Fibrosis
This study highlights the importance of exosomes in IPF pathophysiology.PMID:38117249 | DOI:10.1165/rcmb.2023-0232OC (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 20, 2023 Category: Respiratory Medicine Authors: Hassan Hayek Ohoud Rehbini Beata Kosmider Thomas Brandt Wissam Chatila Nathaniel Marchetti Gerard J Criner Sudhir Bolla Raj Kishore Russell P Bowler Karim Bahmed Source Type: research

BCL-2 Modulates IRE1 α Activation to Attenuate ER Stress and Pulmonary Fibrosis
Am J Respir Cell Mol Biol. 2023 Dec 20. doi: 10.1165/rcmb.2023-0109OC. Online ahead of print.ABSTRACTBCL-2 family members are known to be pro-survival agents in numerous biological settings. Here we provide evidence that in injury and repair processes in lungs, BCL-2 mainly acts to attenuate endoplasmic reticulum (ER) stress and limit extracellular matrix (ECM) accumulation. Days after intratracheal bleomycin mice lose a fraction of their alveolar type II epithelium from terminal ER stress driven by activation of the critical ER sensor and stress effector IRE1-α. This fraction is dramatically increased by BCL-2 inhibition...
Source: Am J Respir Cell Mol... - December 20, 2023 Category: Respiratory Medicine Authors: Claude Jourdan Le Saux Tsung Che Ho Alexis M Brumwell Jaymin J Kathiriya Ying Wei Jun-Wei B Hughes Kiana Garakani Kamran Atabai Vincent C Auyeung Feroz R Papa Harold A Chapman Source Type: research

The Regulation of FASN by Exosomal miR-143-5p and miR-342-5p in Idiopathic Pulmonary Fibrosis
This study highlights the importance of exosomes in IPF pathophysiology.PMID:38117249 | DOI:10.1165/rcmb.2023-0232OC (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 20, 2023 Category: Respiratory Medicine Authors: Hassan Hayek Ohoud Rehbini Beata Kosmider Thomas Brandt Wissam Chatila Nathaniel Marchetti Gerard J Criner Sudhir Bolla Raj Kishore Russell P Bowler Karim Bahmed Source Type: research

BCL-2 Modulates IRE1 α Activation to Attenuate ER Stress and Pulmonary Fibrosis
Am J Respir Cell Mol Biol. 2023 Dec 20. doi: 10.1165/rcmb.2023-0109OC. Online ahead of print.ABSTRACTBCL-2 family members are known to be pro-survival agents in numerous biological settings. Here we provide evidence that in injury and repair processes in lungs, BCL-2 mainly acts to attenuate endoplasmic reticulum (ER) stress and limit extracellular matrix (ECM) accumulation. Days after intratracheal bleomycin mice lose a fraction of their alveolar type II epithelium from terminal ER stress driven by activation of the critical ER sensor and stress effector IRE1-α. This fraction is dramatically increased by BCL-2 inhibition...
Source: Am J Respir Cell Mol... - December 20, 2023 Category: Respiratory Medicine Authors: Claude Jourdan Le Saux Tsung Che Ho Alexis M Brumwell Jaymin J Kathiriya Ying Wei Jun-Wei B Hughes Kiana Garakani Kamran Atabai Vincent C Auyeung Feroz R Papa Harold A Chapman Source Type: research

Mapping a New Course to Understand Lung Biology Mechanisms: LungMAP.net
Am J Respir Cell Mol Biol. 2023 Dec 18. doi: 10.1165/rcmb.2023-0439ED. Online ahead of print.NO ABSTRACTPMID:38109690 | DOI:10.1165/rcmb.2023-0439ED (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 18, 2023 Category: Respiratory Medicine Authors: Sheng Yang Kristina Gaietto Wei Chen Source Type: research

KAT's in the Cradle: p300/CBP and Regulation of HIF-1 and Blood Pressure During Intermittent Hypoxia
Am J Respir Cell Mol Biol. 2023 Dec 18. doi: 10.1165/rcmb.2023-0435ED. Online ahead of print.NO ABSTRACTPMID:38109691 | DOI:10.1165/rcmb.2023-0435ED (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 18, 2023 Category: Respiratory Medicine Authors: Larissa A Shimoda Source Type: research

Bronchopulmonary Dysplasia and Cell Senescence: A Case of Old Lungs in Young Infants?
Am J Respir Cell Mol Biol. 2023 Dec 18. doi: 10.1165/rcmb.2023-0442ED. Online ahead of print.NO ABSTRACTPMID:38109692 | DOI:10.1165/rcmb.2023-0442ED (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 18, 2023 Category: Respiratory Medicine Authors: Paul T Schumacker Source Type: research

Mapping a New Course to Understand Lung Biology Mechanisms: LungMAP.net
Am J Respir Cell Mol Biol. 2023 Dec 18. doi: 10.1165/rcmb.2023-0439ED. Online ahead of print.NO ABSTRACTPMID:38109690 | DOI:10.1165/rcmb.2023-0439ED (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 18, 2023 Category: Respiratory Medicine Authors: Sheng Yang Kristina Gaietto Wei Chen Source Type: research