Lack of S1PR2 in Macrophage Ameliorates Sepsis-associated Lung Injury through Inducing IL-33-mediated Type 2 Immunity
In conclusion, a lack of S1PR2 modulates type 2 immune response by upregulating IL-33 release from macrophages and alleviates sepsis-induced lung injury. Targeting S1PR2 may have a potential therapeutic value for sepsis treatment.PMID:38061028 | DOI:10.1165/rcmb.2023-0075OC (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 7, 2023 Category: Respiratory Medicine Authors: Chenchen Gong Yue Jin Xi Wang Jiali Mao Dongdong Wang Xiangyang Yu Shiyu Chen Yang Wang Daqing Ma Xiangming Fang Kai Zhang Qiang Shu Source Type: research

A < em > NEAT < /em > Discovery Hints at Altered Golgi Signaling in Lung Fibrosis
Am J Respir Cell Mol Biol. 2023 Dec 7. doi: 10.1165/rcmb.2023-0384ED. Online ahead of print.NO ABSTRACTPMID:38060429 | DOI:10.1165/rcmb.2023-0384ED (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 7, 2023 Category: Respiratory Medicine Authors: Claudia A Staab-Weijnitz Source Type: research

Disinherit your Descendants by Rewriting the COPD Epigenetic < em > Script < /em >
Am J Respir Cell Mol Biol. 2023 Dec 7. doi: 10.1165/rcmb.2023-0387ED. Online ahead of print.NO ABSTRACTPMID:38060824 | DOI:10.1165/rcmb.2023-0387ED (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 7, 2023 Category: Respiratory Medicine Authors: Roc ío Fuentes-Mateos Reinoud Gosens Source Type: research

Lack of S1PR2 in Macrophage Ameliorates Sepsis-associated Lung Injury through Inducing IL-33-mediated Type 2 Immunity
In conclusion, a lack of S1PR2 modulates type 2 immune response by upregulating IL-33 release from macrophages and alleviates sepsis-induced lung injury. Targeting S1PR2 may have a potential therapeutic value for sepsis treatment.PMID:38061028 | DOI:10.1165/rcmb.2023-0075OC (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 7, 2023 Category: Respiratory Medicine Authors: Chenchen Gong Yue Jin Xi Wang Jiali Mao Dongdong Wang Xiangyang Yu Shiyu Chen Yang Wang Daqing Ma Xiangming Fang Kai Zhang Qiang Shu Source Type: research

A < em > NEAT < /em > Discovery Hints at Altered Golgi Signaling in Lung Fibrosis
Am J Respir Cell Mol Biol. 2023 Dec 7. doi: 10.1165/rcmb.2023-0384ED. Online ahead of print.NO ABSTRACTPMID:38060429 | DOI:10.1165/rcmb.2023-0384ED (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 7, 2023 Category: Respiratory Medicine Authors: Claudia A Staab-Weijnitz Source Type: research

Disinherit your Descendants by Rewriting the COPD Epigenetic < em > Script < /em >
Am J Respir Cell Mol Biol. 2023 Dec 7. doi: 10.1165/rcmb.2023-0387ED. Online ahead of print.NO ABSTRACTPMID:38060824 | DOI:10.1165/rcmb.2023-0387ED (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 7, 2023 Category: Respiratory Medicine Authors: Roc ío Fuentes-Mateos Reinoud Gosens Source Type: research

Lack of S1PR2 in Macrophage Ameliorates Sepsis-associated Lung Injury through Inducing IL-33-mediated Type 2 Immunity
In conclusion, a lack of S1PR2 modulates type 2 immune response by upregulating IL-33 release from macrophages and alleviates sepsis-induced lung injury. Targeting S1PR2 may have a potential therapeutic value for sepsis treatment.PMID:38061028 | DOI:10.1165/rcmb.2023-0075OC (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 7, 2023 Category: Respiratory Medicine Authors: Chenchen Gong Yue Jin Xi Wang Jiali Mao Dongdong Wang Xiangyang Yu Shiyu Chen Yang Wang Daqing Ma Xiangming Fang Kai Zhang Qiang Shu Source Type: research

Mutual Regulation of Transcriptomes Between Murine Pneumocytes and Fibroblasts Mediates Alveolar Regeneration in Air-Liquid Interface Cultures
Am J Respir Cell Mol Biol. 2023 Dec 5. doi: 10.1165/rcmb.2023-0078OC. Online ahead of print.ABSTRACTAlveolar type 2 (AT2) and club cells are part of the stem cell niche of the lung and their differentiation is required for pulmonary homeostasis and tissue regeneration. A disturbed crosstalk between fibroblasts and epithelial cells contributes to the loss of lung structure in chronic lung diseases. Therefore, it is important to understand how fibroblasts and lung epithelial cells interact during regeneration. Here we analyzed the interaction of fibroblasts and the alveolar epithelium modelled in air-liquid interface culture...
Source: Am J Respir Cell Mol... - December 5, 2023 Category: Respiratory Medicine Authors: Yiwen Yao Sarah Miethe Kathrin Kattler Bet ül Colakoglu J örn Walter Nicole Schneider-Daum Christian Herr Holger Garn Felix Ritzmann Robert Bals Christoph Beisswenger Source Type: research

Mutual Regulation of Transcriptomes Between Murine Pneumocytes and Fibroblasts Mediates Alveolar Regeneration in Air-Liquid Interface Cultures
Am J Respir Cell Mol Biol. 2023 Dec 5. doi: 10.1165/rcmb.2023-0078OC. Online ahead of print.ABSTRACTAlveolar type 2 (AT2) and club cells are part of the stem cell niche of the lung and their differentiation is required for pulmonary homeostasis and tissue regeneration. A disturbed crosstalk between fibroblasts and epithelial cells contributes to the loss of lung structure in chronic lung diseases. Therefore, it is important to understand how fibroblasts and lung epithelial cells interact during regeneration. Here we analyzed the interaction of fibroblasts and the alveolar epithelium modelled in air-liquid interface culture...
Source: Am J Respir Cell Mol... - December 5, 2023 Category: Respiratory Medicine Authors: Yiwen Yao Sarah Miethe Kathrin Kattler Bet ül Colakoglu J örn Walter Nicole Schneider-Daum Christian Herr Holger Garn Felix Ritzmann Robert Bals Christoph Beisswenger Source Type: research

December Highlights/Papers by Junior Investigators/NIH News
Am J Respir Cell Mol Biol. 2023 Dec;69(6):iii. doi: 10.1165/rcmb.69i6RedAlert.NO ABSTRACTPMID:38038397 | DOI:10.1165/rcmb.69i6RedAlert (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 1, 2023 Category: Respiratory Medicine Source Type: research

Single-Cell Transcriptomes, Lineage, and Differentiation of Functional Airway Microfold Cells
Am J Respir Cell Mol Biol. 2023 Dec;69(6):698-701. doi: 10.1165/rcmb.2023-0292LE.NO ABSTRACTPMID:38038398 | DOI:10.1165/rcmb.2023-0292LE (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 1, 2023 Category: Respiratory Medicine Authors: Manalee V Surve Brian Lin Jennifer L Reedy Arianne J Crossen Anthony Xu Bruce S Klein Jatin M Vyas Jayaraj Rajagopal Source Type: research

December Highlights/Papers by Junior Investigators/NIH News
Am J Respir Cell Mol Biol. 2023 Dec;69(6):iii. doi: 10.1165/rcmb.69i6RedAlert.NO ABSTRACTPMID:38038397 | DOI:10.1165/rcmb.69i6RedAlert (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 1, 2023 Category: Respiratory Medicine Source Type: research

Single-Cell Transcriptomes, Lineage, and Differentiation of Functional Airway Microfold Cells
Am J Respir Cell Mol Biol. 2023 Dec;69(6):698-701. doi: 10.1165/rcmb.2023-0292LE.NO ABSTRACTPMID:38038398 | DOI:10.1165/rcmb.2023-0292LE (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 1, 2023 Category: Respiratory Medicine Authors: Manalee V Surve Brian Lin Jennifer L Reedy Arianne J Crossen Anthony Xu Bruce S Klein Jatin M Vyas Jayaraj Rajagopal Source Type: research

December Highlights/Papers by Junior Investigators/NIH News
Am J Respir Cell Mol Biol. 2023 Dec;69(6):iii. doi: 10.1165/rcmb.69i6RedAlert.NO ABSTRACTPMID:38038397 | DOI:10.1165/rcmb.69i6RedAlert (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 1, 2023 Category: Respiratory Medicine Source Type: research

Single-Cell Transcriptomes, Lineage, and Differentiation of Functional Airway Microfold Cells
Am J Respir Cell Mol Biol. 2023 Dec;69(6):698-701. doi: 10.1165/rcmb.2023-0292LE.NO ABSTRACTPMID:38038398 | DOI:10.1165/rcmb.2023-0292LE (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - December 1, 2023 Category: Respiratory Medicine Authors: Manalee V Surve Brian Lin Jennifer L Reedy Arianne J Crossen Anthony Xu Bruce S Klein Jatin M Vyas Jayaraj Rajagopal Source Type: research