Addiction Science and Clinical Practice This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Project CHARIOT: study protocol for a hybrid type 1 effectiveness-implementation study of comprehensive tele-harm reduction for engagement of people who inject drugs in HIV prevention services
The objectives are: (1) to determine if the C-THR intervention increases engagement in HIV prevention (i.e., HIV pre-exposure prophylaxis; PrEP or medications for opioid use disorder; MOUD) compared to non-SSP clinic referral and patient navigation, (2) to examine the long-term effectiveness and cost-effectiveness of the C-THR intervention, and (3) to assess the barriers and facilitators to implementation and sustainment of the C-THR intervention. The co-primary outcomes are PrEP or MOUD engagement across follow-up at 3, 6, 9 and 12 months. For PrEP, engagement is confirmed by tenofovir on dried blood spot or cabotegravir ...
Source: Addiction Science and Clinical Practice - March 26, 2024 Category: Addiction Authors: Tyler S Bartholomew Marina Plesons David P Serota Elizabeth Alonso Lisa R Metsch Daniel J Feaster Jessica Ucha Edward Suarez David W Forrest Teresa A Chueng Katrina Ciraldo Jimmie Brooks Justin D Smith Joshua A Barocas Hansel E Tookes Source Type: research

Hospitalization is a missed opportunity for HIV screening, pre-exposure prophylaxis, and treatment
DISCUSSION: We observed poor provision of HIV testing, PrEP and other HIV services for hospitalized PWID across multiple U.S. medical centers. Future initiatives should focus on providing this group with comprehensive HIV testing and treatment services through a status neutral approach.PMID:38528590 | PMC:PMC10964564 | DOI:10.1186/s13722-024-00451-z (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - March 26, 2024 Category: Addiction Authors: William Bradford Hana Akselrod John Bassler Kelly W Gagnon Greer Burkholder Joseph Edward Carpenter Alaina Steck Jillian Catalanotti Irene Kuo Keanan McGonigle William Mai Melissa Notis Christopher Brokus Sarah Kattakuzhy Elana Rosenthal Ellen F Eaton Source Type: research

Provider perceptions of systems-level barriers and facilitators to utilizing family-based treatment approaches in adolescent and young adult opioid use disorder treatment
CONCLUSIONS: Family-based treatment opportunities for AYA with OUD in Rhode Island are limited. Affordable and accessible training programs are needed to increase provider familiarity and competency with family-based treatment. Implementation of programming to increase family involvement in treatment (i.e. psychoeducational and skills-based groups for family members) rather than adopting a family-based treatment model may be a more feasible step to better meet the needs of AYA with OUD.TRIAL REGISTRATION: not applicable.PMID:38515214 | PMC:PMC10958911 | DOI:10.1186/s13722-024-00437-x (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - March 22, 2024 Category: Addiction Authors: Melissa Pielech Crosby Modrowski Jasper Yeh Melissa A Clark Brandon D L Marshall Francesca L Beaudoin Sara J Becker Robert Miranda Source Type: research

Provider perceptions of systems-level barriers and facilitators to utilizing family-based treatment approaches in adolescent and young adult opioid use disorder treatment
CONCLUSIONS: Family-based treatment opportunities for AYA with OUD in Rhode Island are limited. Affordable and accessible training programs are needed to increase provider familiarity and competency with family-based treatment. Implementation of programming to increase family involvement in treatment (i.e. psychoeducational and skills-based groups for family members) rather than adopting a family-based treatment model may be a more feasible step to better meet the needs of AYA with OUD.TRIAL REGISTRATION: not applicable.PMID:38515214 | DOI:10.1186/s13722-024-00437-x (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - March 22, 2024 Category: Addiction Authors: Melissa Pielech Crosby Modrowski Jasper Yeh Melissa A Clark Brandon D L Marshall Francesca L Beaudoin Sara J Becker Robert Miranda Source Type: research

Treatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to action
Addict Sci Clin Pract. 2024 Mar 19;19(1):19. doi: 10.1186/s13722-024-00448-8.ABSTRACTAlcohol-associated liver disease is currently the leading cause of liver transplantation and liver deaths both in Europe and the United States. Efficacious treatments exist for alcohol use disorder, but they are seldomly prescribed for patients who need them. Besides, the presence of liver cirrhosis can complicate pharmacological treatment choices. In this review, we discuss established and innovative treatment strategies to treat unhealthy alcohol use in patients with alcohol-associated liver disease. We also describe the experience of ou...
Source: Addiction Science and Clinical Practice - March 20, 2024 Category: Addiction Authors: Lamia Y Haque Paola Zuluaga Robert Muga Daniel Fuster Source Type: research

Implementing a pharmacist-integrated collaborative model of medication treatment for opioid use disorder in primary care: study design and methodological considerations
This study seeks to implement a pharmacist integrated MOUD clinical model (called PrIMO) and evaluate its feasibility, acceptability, and impact across four diverse primary care sites. The Consolidated Framework for Implementation Research is used as an organizing framework for study development and interpretation of findings. Implementation Facilitation is used to support PrIMO adoption. We assess the primary outcome, the feasibility of implementing PrIMO, using the Stages of Implementation Completion (SIC). We evaluate the acceptability and impact of the PrIMO model at the sites using mixed-methods and combine survey and...
Source: Addiction Science and Clinical Practice - March 19, 2024 Category: Addiction Authors: Bethany McLeman Phoebe Gauthier Laurie S Lester Felicity Homsted Vernon Gardner Sarah K Moore Paul J Joudrey Lisa Saldana Gerald Cochran Jacklyn P Harris Kathryn Hefner Edward Chongsi Kimberly Kramer Ashley Vena Rebecca A Ottesen Tess Gallant Jesse S Bogg Source Type: research

Treatment setting and buprenorphine discontinuation: an analysis of multi-state insurance claims
CONCLUSION: Buprenorphine discontinuation is high across outpatient PCP, psychiatry, and SUD treatment facility settings, with potentially lower treatment retention among Medicaid enrollees receiving care from SUD facilities and PCPs.PMID:38493109 | PMC:PMC10943881 | DOI:10.1186/s13722-024-00450-0 (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - March 17, 2024 Category: Addiction Authors: Kevin Y Xu Alex K Gertner Shelly F Greenfield Arthur Robin Williams Richard A Grucza Source Type: research

Treatment setting and buprenorphine discontinuation: an analysis of multi-state insurance claims
CONCLUSION: Buprenorphine discontinuation is high across outpatient PCP, psychiatry, and SUD treatment facility settings, with potentially lower treatment retention among Medicaid enrollees receiving care from SUD facilities and PCPs.PMID:38493109 | DOI:10.1186/s13722-024-00450-0 (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - March 17, 2024 Category: Addiction Authors: Kevin Y Xu Alex K Gertner Shelly F Greenfield Arthur Robin Williams Richard A Grucza Source Type: research

Feasibility of precision smoking treatment in a low-income community setting: results of a pilot randomized controlled trial in The Southern Community Cohort Study
CONCLUSIONS: Genetically informed precision smoking cessation interventions are feasible in socioeconomically disadvantaged communities, exhibiting high enrollment, engagement, and retention irrespective of race, sex, income, education, or attitudes toward precision smoking treatment. Future smoking cessation interventions in this population should take steps to engage older people and to sustain participation in interventions that include genetic risk counseling.TRIAL REGISTRATION: ClinicalTrials.gov No. NCT03521141, Registered 27 April 2018, https://www.CLINICALTRIALS: gov/study/NCT03521141.PMID:38491559 | PMC:PMC1094144...
Source: Addiction Science and Clinical Practice - March 16, 2024 Category: Addiction Authors: Scott S Lee Nicole Senft Everson Maureen Sanderson Rebecca Selove William J Blot Stephen King Karen Gilliam Suman Kundu Mark Steinwandel Sarah J Sternlieb Qiuyin Cai Shaneda Warren Andersen Debra L Friedman Erin Connors Kelly Mary Kay Fadden Matthew S Fre Source Type: research

Integrating substance use peer support and screening brief intervention and referral to treatment services in the emergency department: a descriptive study of the ED leads program
CONCLUSIONS: This study describes the potential value and challenges of implementing a blended peer counselor and licensed clinician model in the ED to provide SUD services. While teams provided a high volume of referrals and the analysis of post-intervention treatment follow up is promising, the blended team model was not fully realized, making it difficult to assess the benefits of this combined service. Further research might examine patient outcomes among ED patients who are offered services by both a peer counselor and licensed clinician.PMID:38419101 | PMC:PMC10902983 | DOI:10.1186/s13722-024-00445-x (Source: Addicti...
Source: Addiction Science and Clinical Practice - February 28, 2024 Category: Addiction Authors: Lynsey Avalone Monique Lalane Carla King Kayna Pfeiffer Rebecca Linn-Walton Charles Barron Source Type: research