Model of Calcium Dynamics Regulating [Formula: see text], ATP and Insulin Production in a Pancreatic [Formula: see text]-Cell
Acta Biotheor. 2024 Feb 9;72(1):2. doi: 10.1007/s10441-024-09477-x.ABSTRACTThe calcium signals regulate the production and secretion of many signaling molecules like inositol trisphosphate ([Formula: see text]) and adenosine triphosphate (ATP) in various cells including pancreatic [Formula: see text]-cells. The calcium signaling mechanisms regulating [Formula: see text], ATP and insulin responsible for various functions of [Formula: see text]-cells are still not well understood. Any disturbance in these mechanisms can alter the functions of [Formula: see text]-cells leading to diabetes and metabolic disorders. Therefore, a...
Source: Acta Biotheoretica - February 9, 2024 Category: Biomedical Science Authors: None Vaishali Neeru Adlakha Source Type: research

Model of Calcium Dynamics Regulating [Formula: see text], ATP and Insulin Production in a Pancreatic [Formula: see text]-Cell
Acta Biotheor. 2024 Feb 9;72(1):2. doi: 10.1007/s10441-024-09477-x.ABSTRACTThe calcium signals regulate the production and secretion of many signaling molecules like inositol trisphosphate ([Formula: see text]) and adenosine triphosphate (ATP) in various cells including pancreatic [Formula: see text]-cells. The calcium signaling mechanisms regulating [Formula: see text], ATP and insulin responsible for various functions of [Formula: see text]-cells are still not well understood. Any disturbance in these mechanisms can alter the functions of [Formula: see text]-cells leading to diabetes and metabolic disorders. Therefore, a...
Source: Acta Biotheoretica - February 9, 2024 Category: Biomedical Science Authors: None Vaishali Neeru Adlakha Source Type: research

Model of Calcium Dynamics Regulating [Formula: see text], ATP and Insulin Production in a Pancreatic [Formula: see text]-Cell
Acta Biotheor. 2024 Feb 9;72(1):2. doi: 10.1007/s10441-024-09477-x.ABSTRACTThe calcium signals regulate the production and secretion of many signaling molecules like inositol trisphosphate ([Formula: see text]) and adenosine triphosphate (ATP) in various cells including pancreatic [Formula: see text]-cells. The calcium signaling mechanisms regulating [Formula: see text], ATP and insulin responsible for various functions of [Formula: see text]-cells are still not well understood. Any disturbance in these mechanisms can alter the functions of [Formula: see text]-cells leading to diabetes and metabolic disorders. Therefore, a...
Source: Acta Biotheoretica - February 9, 2024 Category: Biomedical Science Authors: None Vaishali Neeru Adlakha Source Type: research

Model of Calcium Dynamics Regulating [Formula: see text], ATP and Insulin Production in a Pancreatic [Formula: see text]-Cell
Acta Biotheor. 2024 Feb 9;72(1):2. doi: 10.1007/s10441-024-09477-x.ABSTRACTThe calcium signals regulate the production and secretion of many signaling molecules like inositol trisphosphate ([Formula: see text]) and adenosine triphosphate (ATP) in various cells including pancreatic [Formula: see text]-cells. The calcium signaling mechanisms regulating [Formula: see text], ATP and insulin responsible for various functions of [Formula: see text]-cells are still not well understood. Any disturbance in these mechanisms can alter the functions of [Formula: see text]-cells leading to diabetes and metabolic disorders. Therefore, a...
Source: Acta Biotheoretica - February 9, 2024 Category: Biomedical Science Authors: None Vaishali Neeru Adlakha Source Type: research

Model of Calcium Dynamics Regulating [Formula: see text], ATP and Insulin Production in a Pancreatic [Formula: see text]-Cell
Acta Biotheor. 2024 Feb 9;72(1):2. doi: 10.1007/s10441-024-09477-x.ABSTRACTThe calcium signals regulate the production and secretion of many signaling molecules like inositol trisphosphate ([Formula: see text]) and adenosine triphosphate (ATP) in various cells including pancreatic [Formula: see text]-cells. The calcium signaling mechanisms regulating [Formula: see text], ATP and insulin responsible for various functions of [Formula: see text]-cells are still not well understood. Any disturbance in these mechanisms can alter the functions of [Formula: see text]-cells leading to diabetes and metabolic disorders. Therefore, a...
Source: Acta Biotheoretica - February 9, 2024 Category: Biomedical Science Authors: None Vaishali Neeru Adlakha Source Type: research

Integrating Multicellular Systems: Physiological Control and Degrees of Biological Individuality
Acta Biotheor. 2023 Dec 27;72(1):1. doi: 10.1007/s10441-023-09476-4.ABSTRACTThis paper focuses on physiological integration in multicellular systems, a notion often associated with biological individuality, but which has not received enough attention and needs a thorough theoretical treatment. Broadly speaking, physiological integration consists in how different components come together into a cohesive unit in which they are dependent on one another for their existence and activity. This paper argues that physiological integration can be understood by considering how the components of a biological multicellular system are ...
Source: Acta Biotheoretica - December 27, 2023 Category: Biomedical Science Authors: Leonardo Bich Source Type: research

Integrating Multicellular Systems: Physiological Control and Degrees of Biological Individuality
Acta Biotheor. 2023 Dec 27;72(1):1. doi: 10.1007/s10441-023-09476-4.ABSTRACTThis paper focuses on physiological integration in multicellular systems, a notion often associated with biological individuality, but which has not received enough attention and needs a thorough theoretical treatment. Broadly speaking, physiological integration consists in how different components come together into a cohesive unit in which they are dependent on one another for their existence and activity. This paper argues that physiological integration can be understood by considering how the components of a biological multicellular system are ...
Source: Acta Biotheoretica - December 27, 2023 Category: Biomedical Science Authors: Leonardo Bich Source Type: research

Integrating Multicellular Systems: Physiological Control and Degrees of Biological Individuality
Acta Biotheor. 2023 Dec 27;72(1):1. doi: 10.1007/s10441-023-09476-4.ABSTRACTThis paper focuses on physiological integration in multicellular systems, a notion often associated with biological individuality, but which has not received enough attention and needs a thorough theoretical treatment. Broadly speaking, physiological integration consists in how different components come together into a cohesive unit in which they are dependent on one another for their existence and activity. This paper argues that physiological integration can be understood by considering how the components of a biological multicellular system are ...
Source: Acta Biotheoretica - December 27, 2023 Category: Biomedical Science Authors: Leonardo Bich Source Type: research

Integrating Multicellular Systems: Physiological Control and Degrees of Biological Individuality
Acta Biotheor. 2023 Dec 27;72(1):1. doi: 10.1007/s10441-023-09476-4.ABSTRACTThis paper focuses on physiological integration in multicellular systems, a notion often associated with biological individuality, but which has not received enough attention and needs a thorough theoretical treatment. Broadly speaking, physiological integration consists in how different components come together into a cohesive unit in which they are dependent on one another for their existence and activity. This paper argues that physiological integration can be understood by considering how the components of a biological multicellular system are ...
Source: Acta Biotheoretica - December 27, 2023 Category: Biomedical Science Authors: Leonardo Bich Source Type: research

Integrating Multicellular Systems: Physiological Control and Degrees of Biological Individuality
Acta Biotheor. 2023 Dec 27;72(1):1. doi: 10.1007/s10441-023-09476-4.ABSTRACTThis paper focuses on physiological integration in multicellular systems, a notion often associated with biological individuality, but which has not received enough attention and needs a thorough theoretical treatment. Broadly speaking, physiological integration consists in how different components come together into a cohesive unit in which they are dependent on one another for their existence and activity. This paper argues that physiological integration can be understood by considering how the components of a biological multicellular system are ...
Source: Acta Biotheoretica - December 27, 2023 Category: Biomedical Science Authors: Leonardo Bich Source Type: research

Integrating Multicellular Systems: Physiological Control and Degrees of Biological Individuality
Acta Biotheor. 2023 Dec 27;72(1):1. doi: 10.1007/s10441-023-09476-4.ABSTRACTThis paper focuses on physiological integration in multicellular systems, a notion often associated with biological individuality, but which has not received enough attention and needs a thorough theoretical treatment. Broadly speaking, physiological integration consists in how different components come together into a cohesive unit in which they are dependent on one another for their existence and activity. This paper argues that physiological integration can be understood by considering how the components of a biological multicellular system are ...
Source: Acta Biotheoretica - December 27, 2023 Category: Biomedical Science Authors: Leonardo Bich Source Type: research

Integrating Multicellular Systems: Physiological Control and Degrees of Biological Individuality
Acta Biotheor. 2023 Dec 27;72(1):1. doi: 10.1007/s10441-023-09476-4.ABSTRACTThis paper focuses on physiological integration in multicellular systems, a notion often associated with biological individuality, but which has not received enough attention and needs a thorough theoretical treatment. Broadly speaking, physiological integration consists in how different components come together into a cohesive unit in which they are dependent on one another for their existence and activity. This paper argues that physiological integration can be understood by considering how the components of a biological multicellular system are ...
Source: Acta Biotheoretica - December 27, 2023 Category: Biomedical Science Authors: Leonardo Bich Source Type: research

Integrating Multicellular Systems: Physiological Control and Degrees of Biological Individuality
Acta Biotheor. 2023 Dec 27;72(1):1. doi: 10.1007/s10441-023-09476-4.ABSTRACTThis paper focuses on physiological integration in multicellular systems, a notion often associated with biological individuality, but which has not received enough attention and needs a thorough theoretical treatment. Broadly speaking, physiological integration consists in how different components come together into a cohesive unit in which they are dependent on one another for their existence and activity. This paper argues that physiological integration can be understood by considering how the components of a biological multicellular system are ...
Source: Acta Biotheoretica - December 27, 2023 Category: Biomedical Science Authors: Leonardo Bich Source Type: research

Integrating Multicellular Systems: Physiological Control and Degrees of Biological Individuality
Acta Biotheor. 2023 Dec 27;72(1):1. doi: 10.1007/s10441-023-09476-4.ABSTRACTThis paper focuses on physiological integration in multicellular systems, a notion often associated with biological individuality, but which has not received enough attention and needs a thorough theoretical treatment. Broadly speaking, physiological integration consists in how different components come together into a cohesive unit in which they are dependent on one another for their existence and activity. This paper argues that physiological integration can be understood by considering how the components of a biological multicellular system are ...
Source: Acta Biotheoretica - December 27, 2023 Category: Biomedical Science Authors: Leonardo Bich Source Type: research

Integrating Multicellular Systems: Physiological Control and Degrees of Biological Individuality
Acta Biotheor. 2023 Dec 27;72(1):1. doi: 10.1007/s10441-023-09476-4.ABSTRACTThis paper focuses on physiological integration in multicellular systems, a notion often associated with biological individuality, but which has not received enough attention and needs a thorough theoretical treatment. Broadly speaking, physiological integration consists in how different components come together into a cohesive unit in which they are dependent on one another for their existence and activity. This paper argues that physiological integration can be understood by considering how the components of a biological multicellular system are ...
Source: Acta Biotheoretica - December 27, 2023 Category: Biomedical Science Authors: Leonardo Bich Source Type: research