Strategies for an HIV Cure 2020 (Day 1)
The National Institute of Allergy and Infectious Diseases (NIAID) will host the fifth biennial Strategies for an HIV Cure meeting virtually on November 16-17, 2020. The goal of this meeting is to review research progress by grantees funded through the NIH Martin Delaney Collaboratories for HIV Cure Research program and NIAID ’ s Understanding HIV Rebound P01 grant program. November 16th (Day 1) will feature presentations from the NIH Martin Delaney Collaboratories for HIV Cure Research program grantees.Air date: 11/16/2020 10:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - September 15, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Division of Microbiology and Infectious Diseases Subcommittee - September 2020
Report from Division Director and Division StaffAir date: 9/14/2020 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - September 2, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Coping with the Mental Health Effects of COVID-19
NIH is striving to combat the COVID-19 pandemic through a multifaceted approach, by supporting groundbreaking science and research and by promoting the health and safety of NIH staff. This includes ensuring the resources and support needed to manage stress and promote mental health are available. To support this effort, NIH presented this lecture on coping with the mental health effects of the COVID-19 pandemic by Dr. George Everly, Ph.D., followed by a conversation with NIH Director, Dr. Francis Collins. More information on mental health and coping with COVID-19 is available from the following federal agencies: CDC: Me...
Source: Videocast - All Events - August 24, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar - Immunological Mechanisms of Cancer Defense: Reining in Dynamic Cancer Cell and Microenvironment Reciprocity
IIG Seminar The immune system employs two distinct defense strategies against infections: microbe-directed pathogen destruction typified by type 1 immunity, and host-directed pathogen containment exemplified by type 2 immunity in induction of tissue repair. Akin to infectious diseases, cancer progresses with cancer cell acquisition of microorganism-like behavior propagating at the expense of the host. While immunological mechanisms of cancer cell destruction are well defined, whether immune-mediated cancer cell containment can be induced is poorly understood. In this presentation, I will discuss how type 2 immunity can be ...
Source: Videocast - All Events - June 25, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar: Defining malaria vaccine responses by single B cell IG sequencing and plasma IgG proteomics
IIG Seminar Malaria elimination is a global priority and WHO has projected that malaria deaths could double due to COVID19-related health care disruptions. Vaccines have been pivotal for campaigns to eliminate or eradicate other infectious diseases. Malaria transmission blocking vaccines (TBVs) target surface antigens expressed by parasites during their development in mosquitoes in order to interrupt transmission and contribute to malaria elimination. We collected antigen-specific memory B cells from Malian adults immunized with TBV and obtained B cell receptor IG sequences that were used to define the antibody repertoire ...
Source: Videocast - All Events - June 15, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Immunological Mechanisms of Cancer Defense: Reining in Dynamic Cancer Cell and Microenvironment Reciprocity
IIG Seminar The immune system employs two distinct defense strategies against infections: microbe-directed pathogen destruction typified by type 1 immunity, and host-directed pathogen containment exemplified by type 2 immunity in induction of tissue repair. Akin to infectious diseases, cancer progresses with cancer cell acquisition of microorganism-like behavior propagating at the expense of the host. While immunological mechanisms of cancer cell destruction are well defined, whether immune-mediated cancer cell containment can be induced is poorly understood. In this presentation, I will discuss how type 2 immunity can be ...
Source: Videocast - All Events - June 8, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Nucleic Acid Delivery Systems for RNA Therapy and Gene Editing
NIH COVID-19 SIG Lecture Series High throughput, combinatorial approaches have revolutionized small-molecule drug discovery. Dan Anderson will describe his work on the combinatorial development of nanoparticulate, intracellular delivery systems for RNA therapy and gene editing. Libraries of degradable polymers and lipid-like materials have been synthesized, formulated, and screened for their ability to deliver macromolecular payloads inside of cells. These nanoformulations facilitate in vivo delivery, enabling gene suppression with small-interfering RNA, gene expression with messenger RNA, or permanent genetic editing usin...
Source: Videocast - All Events - June 5, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Sailing Close to the Breeze: Hospital Epidemiology in the COVID-19 Pandemic
NIH COVID-19 SIG Lecture Series Dr. Palmore will discuss infection control related to COVID-19. Dr. Palmore began her career at the NIH as a staff clinician in the NIAID Laboratory of Clinical Infectious Diseases. She became deputy hospital epidemiologist in the NIH Clinical Center in 2007 and became hospital epidemiologist in 2014. As hospital epidemiologist, Dr. Palmore aims to optimize patient safety through prevention of hospital-acquired infections. Her research interests include modes of nosocomial transmission of multidrug-resistant bacteria, Clostridium difficile and antimicrobial stewardship.Air date: 5/20/2020 3:...
Source: Videocast - All Events - May 14, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Clinical Trials in Public Health Emergencies: the Ebola and COVID Experiences
NIH COVID-19 SIG Lecture Series Designing and implementing clinical trials for novel infectious disease treatments brings many challenges, especially during a rapidly evolving pandemic. A new disease brings uncertainties arising from an imperfect understanding about illness, limited information about proposed countermeasures, and complexities in measuring relevant patient outcomes. A pandemic adds an overloaded medical system with limited resources for research, heightened pressure to find cures quickly, and unpredictability about potential case numbers. I will discuss issues related to designing and conducting treatment t...
Source: Videocast - All Events - May 11, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Division of Microbiology and Infectious Diseases Subcommittee - June 2020
Report from Division Director and Division StaffAir date: 6/1/2020 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - May 7, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

The Biomedical Research Response to COVID-19: A View from NIAID
NIH COVID-19 SIG Lecture Series NIAID has a long-standing dual mandate to maintain a robust portfolio of research in its key focus areas and to respond to emerging and re-emerging infectious diseases (EIDs). With this mandate, NIAID has also sought to improve EID-response preparedness, working in partnership with other U.S. government research entities, industry, academia, and international public-health organizations. This preparedness planning helped the institute respond rapidly to COVID-19. NIAID tapped existing coronavirus expertise and other assets to stand up research programs spanning basic virology and immunology ...
Source: Videocast - All Events - April 13, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Early-Stage Investigator Lecture: Scaling up HIV Pre-Exposure Prophylaxis to End the HIV Epidemic
ODP 2020 Early-Stage Investigator Lecture Daily oral HIV pre-exposure prophylaxis, or PrEP, is up to 99% effective in preventing HIV transmission and has been approved by the Food and Drug Administration since 2012. However, of the 1.2 million Americans who could benefit from PrEP, less than 20% have used it, and there are substantial racial and ethnic disparities in uptake. Scale-up of PrEP is a critical component of the federal initiative to end the HIV epidemic, but achieving this goal will require effective strategies to improve PrEP implementation. In this presentation, Dr. Marcus will discuss her research on strategi...
Source: Videocast - All Events - March 9, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Early-Stage Investigator Lecture: Scaling up HIV Preexposure Prophylaxis to End the HIV Epidemic
ODP 2020 Early-Stage Investigator Lecture Daily oral HIV pre-exposure prophylaxis, or PrEP, is up to 99% effective in preventing HIV transmission and has been approved by the Food and Drug Administration (FDA) since 2012. However, of the 1.2 million Americans who could benefit from PrEP, less than 20% have used it, and there are substantial racial and ethnic disparities in uptake. Scale-up of PrEP is a critical component of the federal initiative to end the HIV epidemic, but achieving this goal will require effective strategies to improve PrEP implementation. In this presentation, Dr. Marcus will discuss her research on st...
Source: Videocast - All Events - February 28, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

NIAID Clinical Genomics Program: A Data Platform for Public Health
NIAID Clinical Genomics Program The life sciences are in the midst of a data revolution. Inexpensive and accurate genome sequencing is a reality, advanced imaging is routine, and clinical data is increasingly stored in electronic form. In principle, these advances have brought us to the threshold of a new era in medicine, one where the data sciences hold the potential to propel our understanding and treatment of disease. In practice, we are stymied by the operational challenges associated with storing, sharing, and analyzing genomic and clinical data at scale. In this talk, I will overview the Broad Institute's efforts at ...
Source: Videocast - All Events - February 24, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

A Data Platform for Public Health
The life sciences are in the midst of a data revolution. Inexpensive and accurate genome sequencing is a reality, advanced imaging is routine, and clinical data is increasingly stored in electronic form. In principle, these advances have brought us to the threshold of a new era in medicine, one where the data sciences hold the potential to propel our understanding and treatment of disease. In practice, we are stymied by the operational challenges associated with storing, sharing, and analyzing genomic and clinical data at scale. In this talk, I will overview the Broad Institute's efforts at building a data platform to addr...
Source: Videocast - All Events - February 6, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video