Inclusion-Body Myositis Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Imaging beyond muscle magnetic resonance imaging in inclusion body myositis
Clin Exp Rheumatol. 2023 Jan 12. doi: 10.55563/clinexprheumatol/uimkey. Online ahead of print.ABSTRACTDiagnosis of inclusion body myositis (IBM), the most common acquired muscle disorder in adults above the age of 40, remains dependent on demonstration of the classic clinical phenotype and confirmed by muscle histopathological examination. The European Neuromuscular Centre (ENMC) 2011 diagnostic criteria for the diagnosis of IBM includes the demonstration of one or more of the muscle pathological findings - inflammation, vacuolation or protein aggregation. Muscle biopsy is an invasive procedure and patients often require m...
Source: Clinical and Experimental Rheumatology - January 26, 2023 Category: Rheumatology Authors: Namita A Goyal Tahseen Mozaffar Mazen M Dimachkie Source Type: research

Paucity of bulbar function measures in inclusion body myositis trials. Reply to: Current status of clinical outcome measures in inclusion body myositis: a systematised review
Clin Exp Rheumatol. 2023 Jan 24. doi: 10.55563/clinexprheumatol/x66elf. Online ahead of print.NO ABSTRACTPMID:36700648 | DOI:10.55563/clinexprheumatol/x66elf (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - January 26, 2023 Category: Rheumatology Authors: Kendrea L Focht Garand Georgia A Malandraki Kaila L Stipancic Elaine Kearney Bhaskar Roy Lindsay N Alfano Source Type: research

Scleromyositis: A distinct novel entity within the systemic sclerosis and autoimmune myositis spectrum. Implications for care and pathogenesis
Systemic sclerosis and autoimmune myositis are both associated with decreased quality of life and increased mortality. Their prognosis and management largely depend on the disease subgroups. Indeed, systemic sclerosis is a heterogeneous disease, the two predominant forms of the disease being limited and diffuse scleroderma. Autoimmune myositis is also a heterogeneous group of myopathies that classically encompass necrotizing myopathy, antisynthetase syndrome, dermatomyositis and inclusion body myositis. Recent data revealed that an additional disease subset, denominated “scleromyositis”, should be recognized within bot...
Source: Frontiers in Immunology - January 26, 2023 Category: Allergy & Immunology Source Type: research

Low copy numbers of complement C4 and C4A deficiency are risk factors for myositis, its subgroups and autoantibodies
Conclusions C4A deficiency is relevant in dermatomyositis, HLA-DRB1*03 is important in IBM and both C4A deficiency and HLA-DRB1*03 contribute interactively to risk of polymyositis. (Source: Annals of the Rheumatic Diseases)
Source: Annals of the Rheumatic Diseases - January 23, 2023 Category: Rheumatology Authors: Zhou, D., King, E. H., Rothwell, S., Krystufkova, O., Notarnicola, A., Coss, S., Abdul-Aziz, R., Miller, K. E., Dang, A., Yu, G. R., Drew, J., Lundström, E., Pachman, L. M., Mamyrova, G., Curiel, R. V., De Paepe, B., De Bleecker, J. L., Payton, A. Tags: Open access, ARD, Myositis Source Type: research