Impaired health-related quality of life in idiopathic inflammatory myopathies: a cross-sectional analysis from the COVAD-2 e-survey
CONCLUSION: Both physical and mental health are significantly impaired in IIM patients, particularly in those with comorbidities and increased fatigue, emphasizing the importance of patient-reported experiences and optimized multidisciplinary care to enhance well-being in people with IIMs.PMID:38524696 | PMC:PMC10960935 | DOI:10.1093/rap/rkae028 (Source: Adv Data)
Source: Adv Data - March 25, 2024 Category: Epidemiology Authors: Akira Yoshida Yuan Li Vahed Maroufy Masataka Kuwana Syahrul Sazliyana Shaharir Ashima Makol Parikshit Sen James B Lilleker Vishwesh Agarwal Esha Kadam Phonpen Akawatcharangura Goo Jessica Day Marcin Milchert Yi-Ming Chen Dzifa Dey Tsvetelina Velikova Sreo Source Type: research
Impaired health-related quality of life in idiopathic inflammatory myopathies: a cross-sectional analysis from the COVAD-2 e-survey
CONCLUSION: Both physical and mental health are significantly impaired in IIM patients, particularly in those with comorbidities and increased fatigue, emphasizing the importance of patient-reported experiences and optimized multidisciplinary care to enhance well-being in people with IIMs.PMID:38524696 | PMC:PMC10960935 | DOI:10.1093/rap/rkae028 (Source: Adv Data)
Source: Adv Data - March 25, 2024 Category: Epidemiology Authors: Akira Yoshida Yuan Li Vahed Maroufy Masataka Kuwana Syahrul Sazliyana Shaharir Ashima Makol Parikshit Sen James B Lilleker Vishwesh Agarwal Esha Kadam Phonpen Akawatcharangura Goo Jessica Day Marcin Milchert Yi-Ming Chen Dzifa Dey Tsvetelina Velikova Sreo Source Type: research
Polymyositis is a rare and favourable outcome subtype of idiopathic inflammatory myopathy in Chinese patients
CONCLUSIONS: Strictly defined typical PM is a rare clinical subtype in Chinese IIM patients. Typical PM patients with classical pathology were MSA-negative and responded well to treatment and had a favourable prognosis. It is crucial for clinicians to combine clinical, serological, and pathological features to properly distinguish PM from other IIM subtypes.PMID:38488095 | DOI:10.55563/clinexprheumatol/7v9d2x (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 15, 2024 Category: Rheumatology Authors: Chao Sun Xiaolan Tian Hongxia Yang Hanbo Yang Shanshan Li Wei Jiang Qinglin Peng Guochun Wang Xin Lu Source Type: research
272nd ENMC International Workshop: 10 years of Progress - Revision of the ENMC 2013 Diagnostic Criteria for Inclusion Body Myositis and Clinical Trial Readiness. 16-18 June 2023, Hoofddorp, The Netherlands
Inclusion body myositis (IBM) is a rare age-associated myopathy that generally affects people over the age of 45 years [1]. The incidence and prevalence of IBM is increasing, coincident with the increasing age of the global population. However, prevalence is likely underestimated, due in part to the fact that diagnosis currently relies heavily upon myopathologic criteria. There are no specific therapies that modify the disease course, leaving patients and clinicians with supportive treatment of this disabling disorder. (Source: Neuromuscular Disorders)
Source: Neuromuscular Disorders - March 6, 2024 Category: Neurology Authors: James B. Lilleker, Elie Naddaf, Christiaan G.J. Saris, Jens Schmidt, Marianne de Visser, Conrad C. Weihl, the 272nd ENMC workshop participants Source Type: research
Quantitative whole-body muscle MRI in idiopathic inflammatory myopathies including polymyositis with mitochondrial pathology: indications for a disease spectrum
AbstractObjectiveInflammatory myopathies (IIM) include dermatomyositis (DM), sporadic inclusion body myositis (sIBM), immune-mediated necrotizing myopathy (IMNM), and overlap myositis (OLM)/antisynthetase syndrome (ASyS). There is also a rare variant termed polymyositis with mitochondrial pathology (PM-Mito), which is considered a sIBM precursor. There is no information regarding muscle MRI for this rare entity. The aim of this study was to compare MRI findings in IIM, including PM-Mito.MethodsThis retrospective analysis included 41 patients (7 PM-Mito, 11 sIBM, 11 PM/ASyS/OLM, 12 IMNM) and 20 healthy controls. Pattern of ...
Source: Journal of Neurology - March 5, 2024 Category: Neurology Source Type: research
Phenotypic spectrum of inclusion body myositis
Clin Exp Rheumatol. 2024 Feb 28. doi: 10.55563/clinexprheumatol/fhrx3q. Online ahead of print.ABSTRACTInclusion body myositis (IBM) is a progressive, debilitating muscle disease commonly encountered in patients over the age of 50. IBM typically presents with asymmetric, painless, progressive weakness and atrophy of deep finger flexors and/or quadriceps muscle. Many patients with IBM develop dysphagia. However, atypical presentations of IBM with isolated dysphagia, asymptomatic hyper-CKemia, foot drop, proximal weakness, axial weakness, and facial diplegia have been reported. Other acquired and some inherited disorders may ...
Source: Clinical and Experimental Rheumatology - March 4, 2024 Category: Rheumatology Authors: Bhaskar Roy Mazen M Dimachkie Elie Naddaf Source Type: research
