Randomised, double-blind, placebo controlled multi-centre study to assess the efficacy, tolerability and safety of Enterosgel ® in the treatment of irritable bowel syndrome with diarrhoea (IBS-D) in adults
DiscussionThis is the first large scale randomised controlled trial investigating Enterosgel ® in IBS-D. A study design with blinded phase followed by an open-label phase was chosen to encourage participation and study completion. Demonstrating that Enterosgel® is effective and safe in IBS-D could encourage adoption by patients and healthcare professionals and foster future clinical trial s assessing its use in related conditions.Trial registrationISRCTN17149988. Prospectively registered on 14 November 2017. (Source: Trials)
Source: Trials - January 29, 2020 Category: Research Source Type: clinical trials
A Study to Evaluate the Effects of Loperamide (JNJ-289679) on Electrocardiogram Intervals in Healthy Adult Participants
Condition: Healthy Participants Interventions: Drug: Loperamide; Other: Placebo; Drug: Moxifloxacin Sponsor: Janssen Research & Development, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 13, 2020 Category: Research Source Type: clinical trials
