Stress Reactivity and Hormonal Contraception
Conditions: Hormonal Contraception Interventions: Other: Combined oral contraception; Other: Discontinuation of a combined oral contraception Sponsors: University Hospital Tuebingen; Uppsala University; German Research Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2024 Category: Research Source Type: clinical trials
Oxytocin and Reward Processing in Women
Conditions: Menstrual Cycle; Hormonal Contraception Interventions: Drug: Intranasal oxytocin administration; Drug: Intranasal placebo administration Sponsors: International Research Training Group 2804; University Hospital Tuebingen; German Research Foundation; Uppsala University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2024 Category: Research Source Type: clinical trials
Clinical Analysis of Early Hormones Between Patients With Traumatic Brain Injury and Cerebral Hemorrhage
Conditions: Brain Injury Traumatic Diffuse With Loss of Consciousness Interventions: Procedure: trauma Sponsors: General Hospital of Ningxia Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 24, 2024 Category: Research Source Type: clinical trials
A Study to Learn if Elinzanetant Affects the Ability to Drive and Brain Function in Healthy Women
Conditions: Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men; Hot Flashes Interventions: Drug: Elinzanetant (BAY3427080); Drug: Placebo to elinzanetant; Drug: Zopiclone; Drug: Placebo to zopiclone Sponsors: Bayer Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 23, 2024 Category: Research Source Type: clinical trials
Effect of Pulsatile Hormone Administration on Insulin Action
Conditions: Insulin Sensitivity Interventions: Other: Continuous Insulin administration during hyperinsulinemic euglycemic clamp test; Other: Pulsatile Insulin administration during hyperinsulinemic euglycemic clamp test Sponsors: Pennington Biomedical Research Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials
The clinical trial of alternative relugolix administration for uterine leiomyoma prior to surgically treatment: a study protocol for Non-Adverse Relugolix Administration (NARA) trial
This study aims to prove both the non-inferiority in leiomyoma volume reduction and superiority in adverse effects occurrence reduction, which will provide a novel method to escape adverse effects while maintaining the effect of leiomyoma reduction.Trial registrationJapan Registry of Clinical Trials jRCTs051230078. Registered on 26 July 2023. (Source: Trials)
Source: Trials - January 19, 2024 Category: Research Source Type: clinical trials
The Involvement of the Gut Hormone GIP in the Pathophysiology of Post Prandial Hypotension
Conditions: Post Prandial Hypotension Interventions: Other: Intravenous infusion of GIPRA; Other: Intravenous infusion of saline Sponsors: University Hospital, Gentofte, Copenhagen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Evaluating the Addition of Elacestrant (Oral SERD) to Niraparib (PARP-inhibitor) in Patients With Advanced/Metastatic HR+/HER2- Breast Cancer
Conditions: Hormone Receptor Positive HER-2 Negative Breast Cancer; Advanced or Metastatic Breast Cancer; BRCA1 Mutation; BRCA2 Mutation; PALB2 Gene Mutation Interventions: Drug: Niraparib + Elacestrant; Drug: Niraparib Sponsors: German Breast Group; Stemline Therapeutics, Inc.; GlaxoSmithKline Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials
Personalizing the first dose of FSH for IVF/ICSI patients through machine learning: a non-inferiority study protocol for a multi-center randomized controlled trial
This study will be performed in 236 first cycle in vitro fertilization (IVF) and/or ICSI (intracytoplasmic sperm injection) patients, randomized 1:1 in two arms. In the intervention arm, the dose of FSH will be assigned by a machine learning (ML) model called IDoser, while in the control arm, the dose will be determined by the clinician following standard practice. Stratified block randomization will be carried out depending on the patient being classified as expected low responder, high responder, or normo-responder. Patients will complete their participation in the trial once the first embryo transfer result is known. Th...
Source: Trials - January 11, 2024 Category: Research Source Type: clinical trials
Radiotherapy for Prostate and Oligo-metastatic Lesions in Patients With Low-burden Oligo-metastatic Prostate Cancer
Conditions: Oligo-metastatic Prostate Carcinoma Interventions: Radiation: hormone and RT; Drug: ADT combined with abiraterone Sponsors: Changhai Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials
Effect of Low-dose 500 mg Abiraterone Acetate in Treatment of Metastatic Prostate Cancer Patients
Conditions: Prostate Cancer; Metastatic Cancer; Hormone Sensitive Prostate Cancer; Castration-resistant Prostate Cancer Interventions: Drug: Abiraterone Acetate Sponsors: National University Hospital, Singapore; National University of Singapore Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 8, 2024 Category: Research Source Type: clinical trials
A randomized, controlled clinical study of low-molecular-weight heparin improving pregnancy outcomes in PCOS women undergoing IVF: study protocol
The objective of this study is to investigate the effect of LMWH on pregnancy outcomes after invitro fertilization-frozen embryo transfer (IVF-FET) in patients with polycystic ovary syndrome.MethodsA total of 356 PCOS women aged between 20 and 38 years which prepared for IVF followed with FET will be enrolled in the study. The patients, from four different hospitals stratified by age and body mass index (BMI), will be randomly divided into the study group who will be treated with LMWH started on the day of progesterone transformation (hormone therapy) during FET cycle and the control group without additional medicine. Seru...
Source: Trials - January 2, 2024 Category: Research Source Type: clinical trials
Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer
Conditions: Anatomic Stage III Breast Cancer AJCC v8; Anatomic Stage IV Breast Cancer AJCC v8; Locally Advanced Unresectable HER2-Negative Breast Carcinoma; Locally Advanced Unresectable Hormone Receptor-Positive Breast Carcinoma; Metastatic HER2-Negative Breast Carcinoma; Metastatic Hormone Receptor-Positive Breast Carcinoma Interventions: Drug: Abemaciclib; Drug: Anastrozole; Procedure: Biospecimen Collection; Procedure: Computed Tomography; Procedure: Diagnostic Imaging; Drug: Exemestane; Other: Fludeoxyglucose F-18; Drug: Fluorine F 18 Fluoro Furanyl Norprogesterone; Drug: Fulvestrant; Biological: Gonadotropin-releasin...
Source: ClinicalTrials.gov - December 21, 2023 Category: Research Source Type: clinical trials
A Study of the Gut Microbiome in Hormone Receptor-positive HER2-negative Breast Cancer Treated With CDK4/6 Inhibitors
Conditions: Breast Cancer Sponsors: Cliniques universitaires Saint-Luc- Universit é Catholique de Louvain; Jules Bordet Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials
Elucidating Growth Hormone Dynamics at Stages of Progressive Nonalcoholic Fatty Liver Disease
Conditions: Nonalcoholic Fatty Liver Disease Sponsors: Massachusetts General Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 12, 2023 Category: Research Source Type: clinical trials
