A Study of Ribociclib in Combination With Hormonal Therapy in HR+/HER2- Advanced or Metastatic Breast Cancer
Conditions: HR+/HER2- Advanced/Metastatic Breast Cancer Interventions: Other: ribociclib Sponsors: Novartis Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 10, 2023 Category: Research Source Type: clinical trials

A Study to Learn About Novel Hormonal Therapies in People With Metastatic Castration-Sensitive Prostate Cancer (mCSPC)
Conditions: Prostatic Neoplasms Interventions: Drug: Novel hormonal therapy Sponsors: Pfizer; Astellas Pharma Inc Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 9, 2023 Category: Research Source Type: clinical trials

A Multicenter Observational Study on the Development and Health Effects of Premature Ovarian Insufficiency
Conditions: Premature Ovarian Insufficiency Interventions: Drug: hormone replacement therapy Sponsors: Women ' s Hospital School Of Medicine Zhejiang University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 5, 2023 Category: Research Source Type: clinical trials

Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial
Conditions: Prostate Adenocarcinoma; Stage II Prostate Cancer AJCC v8; Stage IIIA Prostate Cancer AJCC v8; Stage IIIB Prostate Cancer AJCC v8 Interventions: Drug: Apalutamide; Procedure: Biospecimen Collection; Procedure: Computed Tomography; Other: Gallium Ga 68 Gozetotide; Radiation: MRI-guided Stereotactic Body Radiation Therapy; Procedure: Multiparametric Magnetic Resonance Imaging; Procedure: Positron Emission Tomography; Other: Questionnaire Administration Sponsors: Jonsson Comprehensive Cancer Center; Janssen Scientific Affairs, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 4, 2023 Category: Research Source Type: clinical trials

Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer
Condition:   Prostate Cancer Interventions:   Drug: DFMO;   Drug: testosterone cypionate;   Drug: Luteinizing hormone-releasing hormone (LHRH) analogue;   Drug: Enzalutamide Sponsors:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;   Panbela Therapeutics;   Prostate Cancer Foundation;   United States Department of Defense Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 28, 2023 Category: Research Source Type: clinical trials

Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer
Conditions: Prostate Cancer Interventions: Drug: DFMO; Drug: testosterone cypionate; Drug: Luteinizing hormone-releasing hormone (LHRH) analogue; Drug: Enzalutamide Sponsors: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Panbela Therapeutics; Prostate Cancer Foundation; United States Department of Defense Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 28, 2023 Category: Research Source Type: clinical trials

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
Conditions: Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage III Breast Cancer AJCC v8; HER2-Negative Breast Carcinoma; Hormone Receptor-Positive Breast Carcinoma Interventions: Procedure: Biospecimen Collection; Drug: Cyclophosphamide; Drug: Doxorubicin; Biological: Durvalumab; Other: Genetic Testing; Procedure: Mammography; Drug: Paclitaxel; Other: Quality-of-Life Assessment Sponsors: National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 28, 2023 Category: Research Source Type: clinical trials

A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats
Condition:   Hot Flashes Interventions:   Drug: Fezolinetant;   Drug: Paroxetine;   Drug: Citalopram;   Drug: Escitalopram;   Drug: Desvenlafaxine;   Drug: Venlafaxine;   Drug: Gabapentin;   Drug: Clonidine;   Drug: Pregabalin;   Drug: Oxybutynin;   Drug: Any other SSRI/SNRI not already specified;   Drug: Any other non-hormonal pharmacologic therapy prescribed for the treatment of VMS not included in a category above Sponsor:   Astellas Pharma Global Development, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials

A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats
Conditions: Hot Flashes Interventions: Drug: Fezolinetant; Drug: Paroxetine; Drug: Citalopram; Drug: Escitalopram; Drug: Desvenlafaxine; Drug: Venlafaxine; Drug: Gabapentin; Drug: Clonidine; Drug: Pregabalin; Drug: Oxybutynin; Drug: Any other SSRI/SNRI not already specified; Drug: Any other non-hormonal pharmacologic therapy prescribed for the treatment of VMS not included in a category above Sponsors: Astellas Pharma Global Development, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials