The epidemiology of primary brain malignancies
Magy Onkol. 2023 Dec 18;67(4):279-287. Epub 2023 Oct 18.ABSTRACTThe occurrence of central nervous system malignancies is relatively low; however, these tumors exhibit poor prognosis and a high mortality rate. On epidemiological grounds, Hungary was placed in the last third among European countries: in the last decade annually 750 to 1000 new cases were diagnosed and the number of deaths was between 550 and 690, without any apparent trends. Age distribution analyses revealed childhood peak and a higher peak at around 65 years of age. Histologically, heterogeneity was apparent, but at least half of the cases were glioblastom...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: Istv án Kenessey Attila Pat ócs M ária Dobozi P éter Nagy Csaba Polg ár Source Type: research

The epidemiology of primary brain malignancies
Magy Onkol. 2023 Dec 18;67(4):279-287. Epub 2023 Oct 18.ABSTRACTThe occurrence of central nervous system malignancies is relatively low; however, these tumors exhibit poor prognosis and a high mortality rate. On epidemiological grounds, Hungary was placed in the last third among European countries: in the last decade annually 750 to 1000 new cases were diagnosed and the number of deaths was between 550 and 690, without any apparent trends. Age distribution analyses revealed childhood peak and a higher peak at around 65 years of age. Histologically, heterogeneity was apparent, but at least half of the cases were glioblastom...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: Istv án Kenessey Attila Pat ócs M ária Dobozi P éter Nagy Csaba Polg ár Source Type: research

The epidemiology of primary brain malignancies
Magy Onkol. 2023 Dec 18;67(4):279-287. Epub 2023 Oct 18.ABSTRACTThe occurrence of central nervous system malignancies is relatively low; however, these tumors exhibit poor prognosis and a high mortality rate. On epidemiological grounds, Hungary was placed in the last third among European countries: in the last decade annually 750 to 1000 new cases were diagnosed and the number of deaths was between 550 and 690, without any apparent trends. Age distribution analyses revealed childhood peak and a higher peak at around 65 years of age. Histologically, heterogeneity was apparent, but at least half of the cases were glioblastom...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: Istv án Kenessey Attila Pat ócs M ária Dobozi P éter Nagy Csaba Polg ár Source Type: research

The epidemiology of primary brain malignancies
Magy Onkol. 2023 Dec 18;67(4):279-287. Epub 2023 Oct 18.ABSTRACTThe occurrence of central nervous system malignancies is relatively low; however, these tumors exhibit poor prognosis and a high mortality rate. On epidemiological grounds, Hungary was placed in the last third among European countries: in the last decade annually 750 to 1000 new cases were diagnosed and the number of deaths was between 550 and 690, without any apparent trends. Age distribution analyses revealed childhood peak and a higher peak at around 65 years of age. Histologically, heterogeneity was apparent, but at least half of the cases were glioblastom...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: Istv án Kenessey Attila Pat ócs M ária Dobozi P éter Nagy Csaba Polg ár Source Type: research

The epidemiology of primary brain malignancies
Magy Onkol. 2023 Dec 18;67(4):279-287. Epub 2023 Oct 18.ABSTRACTThe occurrence of central nervous system malignancies is relatively low; however, these tumors exhibit poor prognosis and a high mortality rate. On epidemiological grounds, Hungary was placed in the last third among European countries: in the last decade annually 750 to 1000 new cases were diagnosed and the number of deaths was between 550 and 690, without any apparent trends. Age distribution analyses revealed childhood peak and a higher peak at around 65 years of age. Histologically, heterogeneity was apparent, but at least half of the cases were glioblastom...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: Istv án Kenessey Attila Pat ócs M ária Dobozi P éter Nagy Csaba Polg ár Source Type: research

The epidemiology of primary brain malignancies
Magy Onkol. 2023 Dec 18;67(4):279-287. Epub 2023 Oct 18.ABSTRACTThe occurrence of central nervous system malignancies is relatively low; however, these tumors exhibit poor prognosis and a high mortality rate. On epidemiological grounds, Hungary was placed in the last third among European countries: in the last decade annually 750 to 1000 new cases were diagnosed and the number of deaths was between 550 and 690, without any apparent trends. Age distribution analyses revealed childhood peak and a higher peak at around 65 years of age. Histologically, heterogeneity was apparent, but at least half of the cases were glioblastom...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: Istv án Kenessey Attila Pat ócs M ária Dobozi P éter Nagy Csaba Polg ár Source Type: research

The epidemiology of primary brain malignancies
Magy Onkol. 2023 Dec 18;67(4):279-287. Epub 2023 Oct 18.ABSTRACTThe occurrence of central nervous system malignancies is relatively low; however, these tumors exhibit poor prognosis and a high mortality rate. On epidemiological grounds, Hungary was placed in the last third among European countries: in the last decade annually 750 to 1000 new cases were diagnosed and the number of deaths was between 550 and 690, without any apparent trends. Age distribution analyses revealed childhood peak and a higher peak at around 65 years of age. Histologically, heterogeneity was apparent, but at least half of the cases were glioblastom...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: Istv án Kenessey Attila Pat ócs M ária Dobozi P éter Nagy Csaba Polg ár Source Type: research

The epidemiology of primary brain malignancies
Magy Onkol. 2023 Dec 18;67(4):279-287. Epub 2023 Oct 18.ABSTRACTThe occurrence of central nervous system malignancies is relatively low; however, these tumors exhibit poor prognosis and a high mortality rate. On epidemiological grounds, Hungary was placed in the last third among European countries: in the last decade annually 750 to 1000 new cases were diagnosed and the number of deaths was between 550 and 690, without any apparent trends. Age distribution analyses revealed childhood peak and a higher peak at around 65 years of age. Histologically, heterogeneity was apparent, but at least half of the cases were glioblastom...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: Istv án Kenessey Attila Pat ócs M ária Dobozi P éter Nagy Csaba Polg ár Source Type: research

Photodynamic Therapy in Treating a Subset of Basal Cell Carcinoma: Strengths, Shortcomings, Comparisons with Surgical Modalities, and Potential Role as Adjunctive Therapy
We present a review of the efficacy of these modalities and describe important considerations that affect the usage of PDT and MMS. ALA-PDT and MAL-PDT are both efficacious treatment options for lower-risk BCC that can serve as non-invasive alternatives to surgical excision with favorable cosmetic outcomes in patients unsuitable to undergo surgery. In particular, PDT may be considered an adjuvant for the prevention and treatment of BCC lesions in patients with some genetic syndromes such as Gorlin syndrome, and in combination with surgical excision in lesions presenting in certain locations. Limitations to PDT include lack...
Source: Cancer Control - December 2, 2023 Category: Cancer & Oncology Authors: Maggie Chen Albert Zhou Amor Khachemoune Source Type: research

Photodynamic Therapy in Treating a Subset of Basal Cell Carcinoma: Strengths, Shortcomings, Comparisons with Surgical Modalities, and Potential Role as Adjunctive Therapy
We present a review of the efficacy of these modalities and describe important considerations that affect the usage of PDT and MMS. ALA-PDT and MAL-PDT are both efficacious treatment options for lower-risk BCC that can serve as non-invasive alternatives to surgical excision with favorable cosmetic outcomes in patients unsuitable to undergo surgery. In particular, PDT may be considered an adjuvant for the prevention and treatment of BCC lesions in patients with some genetic syndromes such as Gorlin syndrome, and in combination with surgical excision in lesions presenting in certain locations. Limitations to PDT include lack...
Source: American Journal of Clinical Dermatology - December 2, 2023 Category: Dermatology Source Type: research

HSD94 Assessing Payer Perspectives on Novel Therapies for the Treatment of Gorlin Syndrome
Explore payer knowledge, perception, and unmet needs related to Gorlin Syndrome (GS) and assess their expectations and evaluation criteria for novel topical therapies. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: M.A. Lopez Pont Source Type: research

Exploring the Changing Diagnostic Criteria of Gorlin-Goltz Syndrome: A Case Report
Oncology (Williston Park). 2023 Nov 8;37(11):449-554. doi: 10.46883/2023.25921007.ABSTRACTGorlin-Goltz syndrome, also known as Gorlin syndrome, basal cell nevus syndrome, and nevoid basal cell carcinoma syndrome, is an autosomal dominant genetic disorder. Its hallmark is an early onset of basal cell carcinoma. Additionally, the syndrome is characterized by a spectrum of distinct clinical attributes encompassing oral, skeletal, ophthalmic, neurological, and developmental aberrations. This condition arises due to anomalies in the Hedgehog signaling pathway, leading to constant pathway activity and uncontrolled growth of tumo...
Source: Oncology (Williston Park, N.Y.) - November 30, 2023 Category: Cancer & Oncology Authors: Sahith Kumar Shetty Vidya G Doddawad Shyam Sundar Shivananda S Source Type: research

Exploring the Changing Diagnostic Criteria of Gorlin-Goltz Syndrome: A Case Report
Oncology (Williston Park). 2023 Nov 8;37(11):449-554. doi: 10.46883/2023.25921007.ABSTRACTGorlin-Goltz syndrome, also known as Gorlin syndrome, basal cell nevus syndrome, and nevoid basal cell carcinoma syndrome, is an autosomal dominant genetic disorder. Its hallmark is an early onset of basal cell carcinoma. Additionally, the syndrome is characterized by a spectrum of distinct clinical attributes encompassing oral, skeletal, ophthalmic, neurological, and developmental aberrations. This condition arises due to anomalies in the Hedgehog signaling pathway, leading to constant pathway activity and uncontrolled growth of tumo...
Source: Oncology (Williston Park, N.Y.) - November 30, 2023 Category: Cancer & Oncology Authors: Sahith Kumar Shetty Vidya G Doddawad Shyam Sundar Shivananda S Source Type: research

Exploring the Changing Diagnostic Criteria of Gorlin-Goltz Syndrome: A Case Report
Oncology (Williston Park). 2023 Nov 8;37(11):449-554. doi: 10.46883/2023.25921007.ABSTRACTGorlin-Goltz syndrome, also known as Gorlin syndrome, basal cell nevus syndrome, and nevoid basal cell carcinoma syndrome, is an autosomal dominant genetic disorder. Its hallmark is an early onset of basal cell carcinoma. Additionally, the syndrome is characterized by a spectrum of distinct clinical attributes encompassing oral, skeletal, ophthalmic, neurological, and developmental aberrations. This condition arises due to anomalies in the Hedgehog signaling pathway, leading to constant pathway activity and uncontrolled growth of tumo...
Source: Oncology (Williston Park, N.Y.) - November 30, 2023 Category: Cancer & Oncology Authors: Sahith Kumar Shetty Vidya G Doddawad Shyam Sundar Shivananda S Source Type: research

Exploring the Changing Diagnostic Criteria of Gorlin-Goltz Syndrome: A Case Report
Oncology (Williston Park). 2023 Nov 8;37(11):449-554. doi: 10.46883/2023.25921007.ABSTRACTGorlin-Goltz syndrome, also known as Gorlin syndrome, basal cell nevus syndrome, and nevoid basal cell carcinoma syndrome, is an autosomal dominant genetic disorder. Its hallmark is an early onset of basal cell carcinoma. Additionally, the syndrome is characterized by a spectrum of distinct clinical attributes encompassing oral, skeletal, ophthalmic, neurological, and developmental aberrations. This condition arises due to anomalies in the Hedgehog signaling pathway, leading to constant pathway activity and uncontrolled growth of tumo...
Source: Oncology (Williston Park, N.Y.) - November 30, 2023 Category: Cancer & Oncology Authors: Sahith Kumar Shetty Vidya G Doddawad Shyam Sundar Shivananda S Source Type: research