Fight Aging! Newsletter, December 7th 2020
In this study, except for the reduction in body weight, the aging characteristics related to epidermal and muscle tissue in mice were significantly ameliorated in the CR group compared with the control group. Additional studies have indicated that not stem cells themselves but the stem cell microenvironment is the key factor mediating stem cell activation, proliferation and differentiation. Mitochondrial dysfunction is an important factor leading to age-related muscular atrophy. Considering the dependence of skeletal muscle on ATP, loss of mitochondrial function, which can lead to a decrease in strength and enduranc...
Source: Fight Aging! - December 6, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Low Dose PPAR γ Agonist Treatment Started in Mid-Life Extends Median Lifespan by 11% in Mice
Researchers here note a modest life extension in mice resulting from long-term treatment with low doses of a PPARγ agonist drug, started in mid-life. This is thought to be an adjustment that acts to suppress inflammation and improve insulin metabolism, both strongly connected to the way in which cellular metabolism determines pace of aging. The size of the effect in mice is small enough to think that it would have little effect on life span in our species, however. Effects derived from this sort of metabolic adjustment have a much larger impact on life span in short-lived species than they do in long-lived species, as mos...
Source: Fight Aging! - November 30, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Wheat Belly “ No Change Rule ” to Reverse Type 2 Diabetes and Accelerate Weight Loss
Follow the simple Wheat Belly No Change Rule for fingerstick blood sugars and you maximize your chances of getting rid of type 2 diabetes and accelerating weight loss. By becoming non-diabetic or at least minimizing it, you are freed from the awful health consequences of this disease, as well as extending life considerably. The No Change Rule also helps reverse insulin resistance that blocks weight loss. Transcript: Hi everybody. Doctor William Davis here. I want to talk about something I call the Wheat Belly “No Change Rule” — that is, no change in blood sugar — comparing a pre-meal to a post-meal blood sugar....
Source: Wheat Belly Blog - January 21, 2019 Category: Cardiology Authors: Dr. Davis Tags: News & Updates diabetes no change rule undoctored Weight Loss wheat belly Source Type: blogs

ZERO tolerance for hypoglycemia
As more and more type 2 diabetics discover the Wheat Belly and other low-carb lifestyles, they are also discovering how rapidly and easily blood sugars drop. As diabetics become less diabetic–a process that can occur VERY quickly, often within 24 hours of removing all wheat/grains from their diet–but they are taking insulin or certain diabetes drugs, there is potential for hypoglycemia or low blood sugar. Low blood sugar from diabetes drugs can be dangerous and should be avoided at all costs. (Imagine if a non-diabetic started administering insulin or blood sugar-reducing drugs–it would result in life-threate...
Source: Wheat Belly Blog - December 23, 2018 Category: Cardiology Authors: Dr. Davis Tags: News & Updates blood sugar diabetes undoctored wheat belly Source Type: blogs

How NOT to have high blood pressure
Patient suffers from hypertension. Woman is measuring blood pressure with monitor. The average American’s lifetime risk for developing high blood pressure is 90%, even using the lax definition of hypertension in clinical studies (that typically don’t label a BP high unless it is 140/90 mmHg or higher, even though we know that, for example, risk for stroke and cardiovascular begin to rise with a systolic, or top, value of only 115 mmHg). Here’s a checklist that, if followed, allow the majority of people with high blood pressure (BP) to reduce both systolic and diastolic values over time and be freed of the...
Source: Wheat Belly Blog - October 31, 2018 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle gluten grains high blood pressure hypertension undoctored Source Type: blogs

Now NOT to have high blood pressure
Patient suffers from hypertension. Woman is measuring blood pressure with monitor. The average American’s lifetime risk for developing high blood pressure is 90%, even using the lax definition of hypertension in clinical studies (that typically don’t label a BP high unless it is 140/90 mmHg or higher, even though we know that, for example, risk for stroke and cardiovascular begin to rise with a systolic, or top, value of only 115 mmHg). Here’s a checklist that, if followed, allow the majority of people with high blood pressure (BP) to reduce both systolic and diastolic values over time and be freed of the...
Source: Wheat Belly Blog - October 31, 2018 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle gluten grains high blood pressure hypertension undoctored Source Type: blogs

MKSAP: 74-year-old woman with altered mental status
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 74-year-old woman is evaluated in the emergency department for several hours of altered mental status. She is from out-of-state and is visiting with relatives. One of her young relatives was recently ill with gastrointestinal symptoms. The patient developed anorexia 3 days ago and vomiting 2 days ago. She has been unable to tolerate any liquid or solid foods for the last 24 hours. Medical history is significant for type 2 diabetes mellitus, hypertension, hyperlipidemia, and hypothyroidism. Medications are aspi...
Source: Kevin, M.D. - Medical Weblog - February 18, 2017 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Diabetes Source Type: blogs

ZERO TOLERANCE for hypoglycemia
Wheat elimination starts you powerfully on the path to reversing diabetes. We’ve seen it many times and it continues to develop in people who kiss their bagels, pretzels, and processed foods booby-trapped with wheat and grains goodbye. But, as diabetics become less diabetic–a process that can occur VERY quickly, often within days of removing all wheat and grain products from their diet–but they are taking insulin or certain diabetes drugs, there is potential for hypoglycemia or low blood sugar. Low blood sugar from diabetes drugs can be dangerous and should be avoided at all costs. (Imagine if a non-diabetic started ...
Source: Wheat Belly Blog - April 2, 2016 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle diabetes glucose gluten grains hypoglycemia insulin Source Type: blogs

The Orange Juice Clue
The parents of a 16-month-old boy who presented to the ED were concerned that he was too sleepy. His initial point-of-care glucose was noted to be 42 mg/dL, and he was somnolent but arousable, and was given orange juice.   Twenty minutes later, the child’s symptoms had completely resolved. Toxicology was consulted for evaluation of a possible toxic ingestion, and a medication inventory was recommended.   Differential Diagnosis of Hypoglycemia in Children n Ethanol intoxication n Beta blocker intoxication n Salicylate toxicity n Sulfonylurea n Insulin injection n Endocrine disorder (hypopituitarism, Addison’...
Source: The Tox Cave - September 1, 2015 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

The Orange Juice Clue
The parents of a 16-month-old boy who presented to the ED were concerned that he was too sleepy. His initial point-of-care glucose was noted to be 42 mg/dL, and he was somnolent but arousable, and was given orange juice.   Twenty minutes later, the child’s symptoms had completely resolved. Toxicology was consulted for evaluation of a possible toxic ingestion, and a medication inventory was recommended.   Differential Diagnosis of Hypoglycemia in Children n Ethanol intoxication n Beta blocker intoxication n Salicylate toxicity n Sulfonylurea n Insulin injection n Endocrine disorder (hypopituitarism, Addison’s disease,...
Source: The Tox Cave - September 1, 2015 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

If you have diabetes: NO low blood sugars!
Wheat elimination starts you powerfully on the path to reversing diabetes. We’ve seen it many times and it continues to develop in people who kiss their bagels, pretzels, and processed foods booby-trapped with wheat goodbye. But, as diabetics become less diabetic–a process that can occur VERY quickly, often within days of removing all wheat products from their diet–but they are taking insulin or certain diabetes drugs, there is potential for hypoglycemia or low blood sugar. Low blood sugar from diabetes drugs can be dangerous and should be avoided at all costs. (Imagine if a non-diabetic started administ...
Source: Wheat Belly Blog - March 28, 2015 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle blood sugar diabetes gluten grains hypoglycemia Source Type: blogs

How NOT to have diabetes
If you want type 2 diabetes , follow conventional advice to cut fat and eat more “healthy whole grains.” (This is also true for type 1 diabetes in susceptible individuals with pancreatic beta cell autoimmunity triggered by wheat gliadin or corn zein.) But what if you don’t want to follow the footsteps of the two thirds of Americans and Canadians who are now diabetic or pre-diabetic? What if you don’t want the expense and side-effects of oral drugs and insulin–one of the most powerful weight gain drugs around? What if you don’t want to lose your eyesight, develop cardiovascular disease, ...
Source: Wheat Belly Blog - January 8, 2015 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle blood sugar bowel flora diabetes gluten-free low-carb resistant starch vitamin D Source Type: blogs

Blood Sugar: Tool at Your Fingertips
Here is an excerpt from Wheat Belly Total Health that discusses how to use a glucose meter to accelerate weight loss. The same strategy can be used to reverse type 2 diabetes as much as possible in as short a time as possible. (Taken from Chapter 7: Grainless Living Day-to-Day.) A blood sugar meter used pre- and post-meal can be a very powerful tool for weight loss and the reversal of metabolic distortions like high blood sugar. But you have to know how to apply the information. Many people are frightened at the prospect of getting their blood checked for anything, and are particularly frightened by the prospect of checkin...
Source: Wheat Belly Blog - October 20, 2014 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle blood sugar diabetes fingerstick glucometer glucose insulin Weight Loss Source Type: blogs

Severe Lows Occur Often in People With Type 2
This study suggests that we should pay much closer attention to hypoglycemia, even in poorly controlled patients. Providers should explain the symptoms of hypoglycemia, how to treat it, and how to avoid it — for example, by not skipping meals. Most of all, providers should ask all their diabetic patients whether they've experienced hypoglycemia, even those patients with very high average levels of blood sugar." The researchers also recommended that evaluations of the quality of diabetes care take into account side effects such as hypoglycemia that are associated with treatment. "While aggressive treatment of high b...
Source: Diabetes Self-Management - August 2, 2013 Category: Diabetes Authors: Diane Fennell Source Type: blogs

Zero tolerance for hypoglycemia
Wheat elimination starts you powerfully on the path to reversing diabetes. We’ve seen it many times and it continues to develop in people who kiss their bagels, pretzels, and processed foods booby-trapped with wheat goodbye. But, as diabetics become less diabetic–a process that can occur VERY quickly, often within days of removing all wheat products from their diet–but they are taking insulin or certain diabetes drugs, there is potential for hypoglycemia or low blood sugar. Low blood sugar from diabetes drugs can be dangerous and should be avoided at all costs. (Imagine if a non-diabetic started administ...
Source: Wheat Belly Blog - July 20, 2013 Category: Cardiology Authors: Dr. Davis Tags: Diabetes Source Type: blogs