Neurofilament Light Chain in Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis; Motor Neuron Disease Interventions: Diagnostic Test: Neurofilament light chain Sponsors: Charite University, Berlin, Germany; Boris Canessa ALS Stiftung Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials
Evaluating the Addition of Elacestrant (Oral SERD) to Niraparib (PARP-inhibitor) in Patients With Advanced/Metastatic HR+/HER2- Breast Cancer
Conditions: Hormone Receptor Positive HER-2 Negative Breast Cancer; Advanced or Metastatic Breast Cancer; BRCA1 Mutation; BRCA2 Mutation; PALB2 Gene Mutation Interventions: Drug: Niraparib + Elacestrant; Drug: Niraparib Sponsors: German Breast Group; Stemline Therapeutics, Inc.; GlaxoSmithKline Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials
Edge AI-deployed DIGItal Twins for PREDICTing Disease Progression and Need for Early Intervention in Infectious and Cardiovascular Diseases Beyond COVID-19 - Investigation of Biomarkers in Dermal Interstitial Fluid
Conditions: Heart Failure Interventions: Device: Use of the PELSA System for dISF extraction Sponsors: Charite University, Berlin, Germany Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials
Impact of Propionic Acid on Regulatory T Cell Function in Healthy Adults ( Pro-Health)
Conditions: Healthy Interventions: Dietary Supplement: Sodium propionate; Other: Placebo Sponsors: Charite University, Berlin, Germany Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials
Overfeeding Induced Fat-tissue Stimulation
Conditions: Lipid-induced Insulin Resistance Interventions: Behavioral: High-fat overnutrition; Behavioral: Normocaloric macronutrient-balanced nutrition Sponsors: German Diabetes Center; Yale University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 5, 2024 Category: Research Source Type: clinical trials
EPAP, Interviewstudy
Conditions: Food Allergy; Food Allergy Peanut; Allergy; Anaphylactic Shock Sponsors: Charite University, Berlin, Germany Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 5, 2024 Category: Research Source Type: clinical trials
Clinical Performance of Injectable Composite Resins in Class I Cavities
Conditions: Caries,Dental Interventions: Device: GC Geanial Injectable (Tokyo,Japan); Device: 3M Filtek Z250 Universal Restoratif (Germany) Sponsors: Hacettepe University Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 5, 2024 Category: Research Source Type: clinical trials
EULAT Eradicate GBC
Conditions: Gallbladder Cancer; Gallstone Disease Interventions: Other: None, observational study. Sponsors: Institut de canc érologie Strasbourg Europe; Heidelberg University Hospital (UKHD, Germany, Coordinator); Universidad Austral de Chile (UACH, Chile); Universidad de la Frontera (UFRO, Chile); Universidad Católica del Maule (UCM, Chile); Centre international de recherche sur le cancer (IARC, France); Universidad de Chile (UChile, Chile); Instituto Nacional de Enfermedades Neoplásicas (INEN, Peru); Universidad Mayor de San Simón (UMSS, Bolivia); Oslo University Hospital; Sanatorio el Carmen (Argentina); Pontificia...
Source: ClinicalTrials.gov - January 5, 2024 Category: Research Source Type: clinical trials
Effects of Bloodletting Acupuncture for Subacute and Chronic Non-specific Low Back Pain
Conditions: Back Pain, Low Interventions: Procedure: Bloodletting acupuncture at the fossa poplitea; Procedure: Bloodletting acupuncture at the regio glutaea Sponsors: Charite University, Berlin, Germany Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 4, 2024 Category: Research Source Type: clinical trials
Functional Imaging to Identify Radiosensitive Esophageal Cancer - a Biomarker Validation Study
Conditions: Esophagus Cancer Interventions: Diagnostic Test: Re Staging FDG-PET Sponsors: Sebastian Zschaeck; Helmholtz Zentrum Dresden Rossendorf, Dresden, Germany Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 4, 2024 Category: Research Source Type: clinical trials
AskBio Phase Ib Trial of AB-1005 Gene Therapy in Patients with Parkinson ’s Disease Meets Primary Endpoint
Berlin, Germany/Research Triangle Park, North Carolina, USA, January 4, 2024– Bayer AG and Asklepios BioPharmaceutical, Inc. (AskBio), a gene therapy company wholly owned and independently operated as a subsidiary of Bayer AG, announced today... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - January 4, 2024 Category: Pharmaceuticals Source Type: clinical trials
Endovascular aortic repair with sac embolization for the prevention of type II endoleaks (the EVAR-SE study): study protocol for a randomized controlled multicentre study in Germany
DiscussionAlthough preexisting studies repeatedly indicated a beneficial effect of SE on T2EL rates after EVAR, patient relevant outcomes have not been assessed until now. The present study is the first randomized controlled multicentre study to assess the impact of SE on quality of life. Further unique features include employment of easily assessable high-risk criteria, a contemporary follow-up protocol, and approval to use any commercially available coil material. Overcoming limitations of previous studies might help SE to be implemented in daily practice and to enhance patient safety.Trial registration ClinicalTrials.go...
Source: Trials - January 2, 2024 Category: Research Source Type: clinical trials
Efficacy of an Online-Based Self-Help Intervention for Auditory Hallucinations in Persons With Psychotic Disorders
Conditions: Psychotic Disorders Interventions: Behavioral: Online-Based Self-Help Intervention Sponsors: Charite University, Berlin, Germany; Elsa-Neumann scholarship of the federal state of Berlin, Doctoral funding.; Charit é - University Medicine Berlin, Medical scientist program. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 1, 2024 Category: Research Source Type: clinical trials
International Active Surveillance Study: Safety of Estrogen Estetrol (E4) Contraceptive Study (INAS-SEECS)
Conditions: Contraception Sponsors: Center for Epidemiology and Health Research, Germany; Estetra Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 29, 2023 Category: Research Source Type: clinical trials
Bioequivalence Study of Empagliflozin 25 mg Film Coated Tablets of Humanis, Turkey and Jardiance (Empagliflozin) 25 mg Film-coated Tablets of Boehringer Ingelheim International GmbH, Germany in Normal, Healthy, Adult, Human Subjects Under Fasting Condition
Conditions: Type2 Diabetes Mellitus Interventions: Drug: Empagliflozin film coated tablets; Drug: Jardiance film-coated tablets Sponsors: Humanis Sagl ık Anonim Sirketi Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 22, 2023 Category: Research Source Type: clinical trials
