TWiV 1095: Monkeys fly and mice exaggerate
TWiV reviews heterosexual transmission of clade I Mpox virus, continued circulation of oropouche virus in South America, herpesviruses in South American fur seals and sea lions, sex-specific differences in physiological responses to SARS-CoV-2 infection, underdetected dispersal and extensive local transmission drove the 2022 mpox epidemic, and a humanized mouse model for adenovirus-associated virus gene therapy. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode M...
Source: This Week in Virology - MP3 Edition - March 10, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Ancient DNA solves the mystery of who made a set of stone tools
In this episode:0:48 How hominins spread through EuropeAncient stone tools are often uncovered in Europe, but it can be difficult to identify who crafted them, as Neanderthals and Homo sapiens coexisted in the region for several thousand years. The makers of one type of tool found in northern Europe has long puzzled researchers, but now through genetic analysis of nearby skeletal fragments, it has been revealed that they were made by Homo sapiens. The age of these tools suggests that modern humans were more widespread and adaptable to living in colder climates than previously thought.Research article: Mylopotamitaki et al....
Source: Nature Podcast - January 31, 2024 Category: Science Authors: Springer Nature Limited Source Type: podcasts
TWiV 1028: Asymptomatic SARS-CoV-2 infection and T cells
TWiV reviews approvals of the first gene therapy for severe hemophilia A in adults and a monoclonal antibody to prevent RSV respiratory disease in babies and toddlers, and a common allele of HLA that mediates asymptomatic SARS-CoV-2 infection through pre-existing T cell immunity due to previous exposure to common cold coronaviruses. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server First gene therapy for hemophilia A approved (FDA) Lux...
Source: This Week in Virology - MP3 Edition - July 23, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Audio long read: Conquering Alzheimer ’s — a look at the therapies of the future
Last year, researchers announced that the Alzheimer’s drug lecanemab lowered the amount of amyloid protein plaques associated with the disease in the brains of participants in a clinical trial, and slowed their cognitive decline.Now, researchers are looking to drug combinations, vaccines and gene therapy to tackle different stages of the disease, as they forge the next generation of treatments for the condition.This is an audio version of our Feature: Conquering Alzheimer’s: a look at the therapies of the future Hosted on Acast. See acast.com/privacy for more information. (Source: Nature Podcast)
Source: Nature Podcast - April 28, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts
Cities as biodiversity havens, and gene therapy for epilepsy
On this week’s show: How urban spaces can help conserve species, and testing a gene therapy strategy for epilepsy in mice
First up on the podcast, we explore urban ecology’s roots in Berlin. Contributing Correspondent Gabriel Popkin joins host Sarah Crespi to discuss turning wastelands and decommissioned airports into forests and grasslands inside the confines of a city.
Next, we hear about a gene therapy strategy for epilepsy. Yichen Qiu, a recently graduated Ph.D. student and researcher at University College London, talks about introducing a small set of genes into neurons in mice. These genes detect hyperactivity ...
Source: Science Magazine Podcast - November 3, 2022 Category: Science Authors: Science Magazine Source Type: podcasts
Cities as biodiversity havens, and gene therapy for epilepsy
On this week’s show: How urban spaces can help conserve species, and testing a gene therapy strategy for epilepsy in mice
First up on the podcast, we explore urban ecology’s roots in Berlin. Contributing Correspondent Gabriel Popkin joins host Sarah Crespi to discuss turning wastelands and decommissioned airports into forests and grasslands inside the confines of a city.
Next, we hear about a gene therapy strategy for epilepsy. Yichen Qiu, a recently graduated Ph.D. student and researcher at University College London, talks about introducing a small set of genes into neurons in mice. These genes detect hyperactivity ...
Source: Science Magazine Podcast - November 3, 2022 Category: Science Authors: Science Magazine Source Type: podcasts
TWiV 697: The sky is NOT falling
TWiV reviews the latest data on the UK variant of SARS-CoV-2, including some properties of the variant and why it is being closely studied, development of liver cancer in a participant in a adenovirus-associated virus gene therapy trial, and answers to listener questions. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode BSL-3 Assistant Manager position 3:39 NERVTAG meeting minutes (pdf) NERVTAG Preliminary genomic characterization of UK variant (virological.org) PHE investigation of UK var...
Source: This Week in Virology - MP3 Edition - December 24, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
ASFH Gene Therapy in Clinical Practice
Guest: Mark Pennesi, M.D., Ph.D. Associate Professor of Ophthalmology, School of Medicine Casey Eye Institute, School of Medicine Oregon Health & Science University Portland, Oregon (Source: As Seen From Here)
Source: As Seen From Here - June 15, 2020 Category: Opthalmology Authors: JYoungMD at gmail.com Source Type: podcasts
TWiV 544: Immunogaga
The TWiV team reveals the repertoire of anti-viral antibodies in newborn humans, and a complement protein that binds the adenovirus capsid and prevents release of the viral DNA. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Maternal anti-viral antibodies in newborns (Nat Med) Complement protein blocks adenovirus uncoating (Cell Host Micr) Antibodies neutralize virus inside cells (virology blog) Image credit Letters read on TWiV 544 Timestamps by Jolene. Thanks! Weekly Science Picks Bria...
Source: This Week in Virology - MP3 Edition - April 21, 2019 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
"Spidey Sense" -- The Discovery Files
With the increasing accessibility of DNA sequencing, University of Cincinnati biologists are unraveling many evolutionary mysteries behind the complex world of spider vision. To further research into gene therapies for visual disorders in humans, scientists have looked 500-million-years into the past to a time called the Cambrian Period to put the evolution of spider eye genes into perspective. (Source: The Discovery Files)
Source: The Discovery Files - February 2, 2018 Category: Science Authors: National Science Foundation Source Type: podcasts
Gene therapy for retinal dystrophy: The Lancet: January 5, 2018
Rebecca Cooney discusses the newly FDA-approved gene therapy for treating loss of vision as a result of retinal dystrophy. (Source: Listen to The Lancet)
Source: Listen to The Lancet - January 6, 2018 Category: General Medicine Authors: The Lancet Source Type: podcasts
TWiV 469: Mycovirus stuffed potatoes
The TWiV hosts discuss a plant virus that infects a fungus, and whether you need to work insane hours to succeed in science. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode Phytopathogenic fungus hosts a plant virus (PNAS) Franklin column (PNAS) Potato famine mystery solved (History) Protein Data Bank You do not need to work 80 hours per week (THE) How I Learned To Stop Worrying (Sci Am) Image credit: Truth Wins by Jon Yewdell Letters read on TWiV 469 This episode is brought to you by the Department of Microbiology at the I...
Source: This Week in Virology - MP3 Edition - November 26, 2017 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 468: Zika by the slice
Amy joins the TWiV team to talk about her career and her work on Zika virus neurotropism using embryonic mouse organotypic brain slice cultures. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Guest: Amy Rosenfeld Become a patron of TWiV! Links for this episode Grad students face tax hike (Nature) House voted to bankrupt grad students (NYTimes) Neurotropism of early and late Zika virus isolates (PNAS) Zika virus blocks the neuron road (virology blog) Letters read on TWiV 468 This episode is brought to you by the Department of Microbiology at the Icahn School of Medicin...
Source: This Week in Virology - MP3 Edition - November 19, 2017 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
