U.S. FDA lowers starting dose of sleep drug Lunesta over safety
(Reuters) - U.S. health regulators on Thursday said they required a label change for the sleep drug Lunesta to cut the recommended starting dose over concerns it could impair alertness in some people the following morning. (Source: Reuters: Health)
Source: Reuters: Health - May 15, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

FDA requiring lower starting dose for sleep drug Lunesta
The U.S. Food and Drug Administration today announced it required the manufacturer of the sleep drug Lunesta (eszopiclone) to change the drug label and lower the current recommended starting dose. Data show that eszopiclone levels in some patients may be high enough the morning after use to impair activities that require alertness, including driving, even if they feel fully awake. (Source: Food and Drug Administration)
Source: Food and Drug Administration - May 15, 2014 Category: American Health Source Type: news

Dr Reddy's launches insomnia drug in US; Glenmark gets FDA nod
The company has started selling 1 mg, 2 mg and 3 mg tablets of Eszopiclone, a generic version of Lunesta, a sedative drug that is used for the treatment of insomnia. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - April 16, 2014 Category: Pharmaceuticals Source Type: news

Why You Don't Need Those Sleeping Pills
It's an easy trap to fall into. You have a bad night of sleep and before you know it, this stretches into a run of bad nights. You try to observe good sleep hygiene, making a few changes to make things better, but your insomnia persists. You mention it to your doctor and you receive a prescription for a sleeping pill. Then the real trouble begins. Sleeping pills are one of the most widely prescribed medications in the world. In a recent report by the Centers for Disease Control and Prevention, it was estimated that between 2005 and 2010 about 4 percent of U.S. adults aged 20 and older used sleeping pills in the previous m...
Source: About Sleep Disorders - October 8, 2013 Category: Sleep Medicine Source Type: news

Reddy's will infringe on Lunesta's patent: US court
The United States Court of Appeals for the Federal Circuit has ruled that Dr Reddy's Laboratories Ltd will (rpt will) infringe on the patent of Sunovion Pharmaceuticals blockbuster drug Lunesta. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - September 27, 2013 Category: Pharmaceuticals Source Type: news

Experimental sleep drug may cause fewer side effects: Merck study
CHICAGO (Reuters) - A study in rats and monkeys suggests an experimental Merck & Co sleep drug may help induce sleep without causing the memory loss and attention problems sometimes seen in the commonly used drugs Ambien and Lunesta, company researchers said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - April 3, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Certain Sleep Aids May Raise Hip Fracture Risk in Nursing Homes
List includes common drugs such as Lunesta and Ambien, researchers say Source: HealthDay Related MedlinePlus Pages: Fractures, Insomnia, Nursing Homes (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 4, 2013 Category: Consumer Health News Source Type: news

Review of Z-drug toxicology
4 out of 5 stars The Clinical and Forensic Toxicology of Z-drugs. Gunja N.┬áJ Med Toxicol 2013 Feb 13 [Epub ahead of print] Abstract This well done article is the most comprehensive discussion I’ve seen about the pharmacology and toxicology of the so-called Z-drugs: zolpidem (Ambien), zopiclone (Imovane), and zaleplon (Sonata). It also touches on eszopiclone (Lunesta), the active enantiomer of zopiclone. All these drugs are non-benzodiazepine sedative-hypnotic agents that act as agonists at the GABAA receptor. These drugs tend to have relatively short durations, making them effective at inducing but not necessarily m...
Source: The Poison Review - February 20, 2013 Category: Toxicology Authors: Leon Tags: Medical overdose pharmacology toxicology zaleplon zolpidem zopiclone Source Type: news