Research and Reviews in the Fastlane 052
This study looked at compliance with discharge instructions. Surprisingly (or maybe not so), 39% of pediatric patients returned to play (RTP) on the day of the injury. RTP is widely recognized as a risk for recurrent and more severe concussions as well as significant morbidity. It is the duty of the Emergency Physician to stress the importance of discharge instructions as well as the importance of appropriate follow up.
Recommended by: Anand Swaminathan
PediatricsSingleton T et al. Emergency department care for patients with hemophilia and von Willebrand disease. J Emerg Med. 2010; 39(2): 158-65. PMID: 18757163
Bleeding...
Source: Life in the Fast Lane - October 9, 2014 Category: Emergency Medicine Authors: Nudrat Rashid Tags: Administration Anaesthetics Cardiology Clinical Research Education Emergency Medicine Haematology Infectious Disease Intensive Care International Emergency Medicine Microbiology Neurosurgery Obstetrics / Gynecology Ophthalmology Source Type: blogs
Can Our Dysfunctional Health Care System Contain Ebola?
Not to bury the lede, I think it can, but it will be a lot harder than the talking heads on television predict.I have been writing about health care dysfunction since 2003. Lots of US politicians would have us believe we have the best health care system in the world (e.g., House of Representatives Speaker John Boehner (R-Ohio), here), Much of the commentary on Ebola also seems based on this "best health care system in the world" notion. For example, in an interview today (5 October, 2014) on Meet the Press, Dan Pfieffer, "senior White House adviser," saidThere is no country in the world better prepa...
Source: Health Care Renewal - October 6, 2014 Category: Health Management Tags: Ebola virus financialization generic managers ill-informed management perverse incentives public health organizations Source Type: blogs
Ebola Update
Trends-in-Medicine is offering updates on Ebola, which recently has shown up inside the United States. We don’t normally cover this type of story on Policy and Medicine, but found Lynne Peterson’s articles to provide important information from the Centers for Disease Control and Prevention (CDC). CDC itself is providing daily updates as well, and we have offered some additional coverage of the latest news about Ebola’s spread into the United States.
On October 2, the CDC confirmed that the first case of this strain of Ebola outside of Africa has been diagnosed, and that patient is in Dallas, Texas. The New York Times...
Source: Policy and Medicine - October 3, 2014 Category: American Health Authors: Thomas Sullivan Source Type: blogs
Could the Ebola virus epidemic have been prevented?
The cover of this week’s issue of Businessweek declares that ‘Ebola is coming’ in letters colored like blood, with the subtitle ‘The US had a chance to stop the virus in its tracks. It missed’. Although the article presents a good analysis of the hurdles in developing antibody therapy for Ebola virus infection, the cover is overstated. Why does Businessweek think that Ebola virus is coming to the US? (there is no mention of this topic in the article). Are we sure that antibody therapy would have stopped the outbreak? (no, as stated in the article).
How the U.S. Screwed Up in the Fight Against Ebola is an analysi...
Source: virology blog - September 30, 2014 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Commentary Information antiviral ebola virus ebolavirus epidemic monoclonal antibody therapy outbreak vaccine West Africa ZMapp Source Type: blogs
Ebola: Don’t forget the patients who are left behind
Ebola virus is rampant in West Africa. So far, the death toll is around 2,296, which makes it one of the largest outbreaks ever. Ebola is what’s known as a hemorrhagic fever virus, and belongs to a large family of nasty viruses that are widespread around the world. There’s even one in the American Southwest known as hantavirus, that lives in a species of mice. Yellow fever, which killed so many before a vaccine was developed, was once widespread as far north as Detroit. Some of these viruses are extremely deadly and some less so, but all of them are dangerous and miserable to endure.
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Your patients...
Source: Kevin, M.D. - Medical Weblog - September 20, 2014 Category: Journals (General) Authors: Edwin Leap, MD Tags: Conditions Infectious disease Source Type: blogs
What we are not afraid to say about Ebola virus
In a recent New York Times OpEd entitled What We’re Afraid to Say About Ebola, Michael Osterholm wonders whether Ebola virus could go airborne:
You can now get Ebola only through direct contact with bodily fluids. If certain mutations occurred, it would mean that just breathing would put one at risk of contracting Ebola. Infections could spread quickly to every part of the globe, as the H1N1 influenza virus did in 2009, after its birth in Mexico.
Is there any truth to what Osterholm is saying?
Let’s start with his discussion of Ebola virus mutation:
But viruses like Ebola are notoriously sloppy in replicating, me...
Source: virology blog - September 19, 2014 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information aerosol transmission airborne transmission ebola virus evolution hemorrhagic fever Michael Osterholm mutation viral Source Type: blogs
"Accelerating Medicines Partnership" and other Collaborations to Speed Discovery of New Therapies
AMP - Accelerating Medicines Partnership
In February, we wrote about the National Institutes of Health (NIH) announcement of a partnership with ten drug makers, as well as eight non-profit organizations, to accelerate the discovery of new therapies for Alzheimer's disease, type 2 diabetes, rheumatoid arthritis, and lupus. Under the collaboration, termed the Accelerating Medicines Partnership (AMP), the companies and the NIH have agreed to contribute scientists, along with relevant data and samples from clinical trials, and to share costs. The goal is to transform the current model for developing new...
Source: Policy and Medicine - September 19, 2014 Category: American Health Authors: Thomas Sullivan Source Type: blogs
TWiV 302: The sky is falling
On episode #302 of the science show This Week in Virology, the TWiVers discuss the growing Ebola virus outbreak in West Africa, and an epidemic of respiratory disease in the US caused by enterovirus D68.
You can find TWiV #302 at www.twiv.tv. (Source: virology blog)
Source: virology blog - September 14, 2014 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology aerosol transmission bsl3 bsl4 containment ebola virus enterovirus D68 hemorrhagic fever mutation outbreak picornavirus respiratory disease vaccine viral West Africa Source Type: blogs
The CDC: A Truly Corrupt and Dangerous Organization
Conclusion
It is clear that the CDC cannot be trusted when it comes to giving advice about vaccinations. Over the years, evidence has shown that the CDC continually lies, withholds evidence and fixes data to obtain the results that they want to achieve.
Due to their continual dishonesty, many children have suffered lifelong disabilities as a result. Although, for many of their parents, the latest revelations have offered a glimmer of hope in a very dark world, it has also caused many parents to just break down and weep, like one mother known to myself.
This is a tragic waste of the future potential of thousands of children...
Source: vactruth.com - September 11, 2014 Category: Allergy & Immunology Authors: Christina England Tags: Christina England Top Stories autism Centers for Disease Control (CDC) Guillian-Barre syndrome miscarriage Polio Thimerosal truth about vaccines Vaccine-associated Polio Paralysis (VAPP) Source Type: blogs
4 reasons why the Ebola vaccine won’t matter
“Dr. Sevilla, what do you think about the Ebola virus,” a patient recently asked me. My patient and I talked about the recent news reports stating that over 1,500 people have died because of the virus.
“There’s a vaccine that’s being developed,” I told my patient.
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Your patients are rating you online: How to respond. Manage your online reputation: A social media guide. Find out how. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - September 8, 2014 Category: Journals (General) Authors: Mike Sevilla, MD Tags: Conditions Infectious disease Source Type: blogs
No #AAAS and ASM you do not deserve good PR for freeing up a few papers on Ebola
Saw a PR from AAAS about how they were freeing up all of ~ 20 papers on Ebola In light of what has become the largest Ebola outbreak on record, Science and Science Translational Medicine have compiled over a decade's worth of their published news and research. Researchers and the general public can now view this special collection for free.OK. More access is good. But alas, they did not even free up all papers in #AAAS journals with Ebola in the Title or Abstract.And then I started thinking. What about HIV? TB? Malaria? And as I started Tweeting about this, I saw that ASM also was hopping on the "free Ebola" bandwago...
Source: The Tree of Life - August 20, 2014 Category: Medical Scientists Authors: Jonathan Eisen Source Type: blogs
Ebola and Marburg Viruses: Molecular and Cellular Biology
Ebola and Marburg Viruses: Molecular and Cellular Biology Publisher: Horizon Bioscience Editor: Hans-Dieter Klenk and Heinz Feldmann ISBN: 978-1-904933-49-6 (ebook) ebook Ebola and Marburg viruses cause severe haemorrhagic fevers. Much research has been performed in recent years on the molecular and genetic properties of these viruses and in particular has focused on molecular structure, replication and virus-host interactions. This book presents a comprehensive review of research on these highly virulent viruses. Topics covered include the genomics and molecular biology of filoviruses, pathogenesis, replication, epidemio...
Source: Microbiology Blog: The weblog for microbiologists. - August 19, 2014 Category: Microbiology Source Type: blogs
Big and Little Pharma Race for Ebola Vaccines and Cures
For a really good summary of what drug manufacturers big and small are doing to develop Ebola vaccines and drugs to stem the growing catastrophe of the Ebola virus outbreak, read this article by Scott Gottlieb, MD.
He discusses the recent donation of 1000 doses of a vaccine developed by the Canadian government, the status of the ZMAPP drug given to Americans Dr. Kent Brantly and Nancy Writebol, vaccine efforts by Danish firm Bavarian Nordic, phase I clinical trials being planned for a vaccine manufactured by GlaxoSmithKline, and the unfortunate discontinuation of an Ebola treatment made by Sarepta because of a lack of fund...
Source: Inside Surgery - August 19, 2014 Category: Surgery Authors: Editor Tags: Infectious Disease Medical News Wire Bavarian Nordic Canadian government Ebola sarepta Scott Gottlieb vaccines ZMAPP Source Type: blogs
TWiV 298: MV-NIS de myelo
On episode #298 of the science show This Week in Virology, the TWiV gang answers follow-up questions about the Ebola virus outbreak in West Africa, then discuss treatment of disseminated multiple myeloma with oncolytic measles virus.
You can find TWiV #298 at www.twiv.tv. (Source: virology blog)
Source: virology blog - August 17, 2014 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral Ebola Guinea hemorrhagic fever Liberia measles virus multiple myeloma oncolytic oncotherapy Sierra Leone vaccine Source Type: blogs
Ebola Outbreak Increases Pressure to Start Vaccine Trials
The world's worst outbreak of Ebola is increasing pressure on researchers to accelerate the development of therapeutic interventions.
Read the rest of the story... » (Source: Highlight HEALTH)
Source: Highlight HEALTH - August 15, 2014 Category: Medical Scientists Authors: Jenny Jessen Source Type: blogs
