Rhabdomyolysis risk with donepezil double that of other AD meds
Rhabdomyolysis more likely in those starting donepezil compared with rivastigmine or galantamine Related items fromOnMedica Suicide no more likely in men on 5 α-reductase inhibitors NICE calls for safer use of controlled drugs Falls risk just as high with trazodone as antipsychotics Over 75s not taking medication correctly, say GPs Debate goes on over valproate in pregnancy (Source: OnMedica Latest News)
Source: OnMedica Latest News - September 15, 2019 Category: UK Health Source Type: news

Study: Alzheimer's drug Aricept could reverse alcohol effects on young brains
An drug used to treat Alzheimer's disease could help reverse some of the negative effects of adolescent binge drinking on the brain, a study published Tuesday indicates. (Source: Health News - UPI.com)
Source: Health News - UPI.com - August 20, 2019 Category: Consumer Health News Source Type: news

Alzheimer's drug 'can reverse some of the brain damage caused by drinking too much alcohol'
Scientists at Duke University in the US gave donepezil to rats who had been exposed to excessive quantities of alcohol over the course of 16 days. (Source: the Mail online | Health)
Source: the Mail online | Health - August 20, 2019 Category: Consumer Health News Source Type: news

Prolonged QT syndrome due to donepezil: a reversible cause of falls? - Jackson EG, Stowe S.
We report a case of prolonged QT syndrome caused by donepezil which resulted in a fall and hip fracture. In this case... (Source: SafetyLit)
Source: SafetyLit - January 21, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Donepezil monotherapy for neurocognitive deficits and psychobehavioral disinhibition in an adolescent posttraumatic brain injury - Naguy A.
[Abstract unavailable] Language: en... (Source: SafetyLit)
Source: SafetyLit - June 18, 2018 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Dementia Drug for Alcohol-Related Brain Damage? Dementia Drug for Alcohol-Related Brain Damage?
Heavy alcohol use in teens leads to long-lasting structural and genetic changes in the brain that may be reversed with a short course of donepezil, early research suggests.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 20, 2018 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Does it matter when my father takes donepezil?
SPONSORED. (Source: the Mail online | Health)
Source: the Mail online | Health - October 17, 2017 Category: Consumer Health News Source Type: news

Study ranks safety, effectiveness of cognitive enhancers for Alzheimer's
(St. Michael's Hospital) A new study ranking the safety and effectiveness of four drugs taken to enhance concentration, memory, alertness and moods, found that donepezil was most likely to effectively improve cognition in patients with Alzheimer's disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 29, 2017 Category: International Medicine & Public Health Source Type: news

Corium touts clinical data for transdermal delivery of Alzheimer ’s drug
Corium (NSDQ:CORI) touted data today from a pilot bioequivalence study, comparing its Corplex Donepezil transdermal patch to oral Aricept as delivery method for the most commonly prescribed treatment for Alzheimer’s disease. Data from the pilot study demonstrated that Corium’s transdermal patch met the criteria for bioequivalence to oral Aricept, as measured by primary pharmacokinetic endpoints previously established by the FDA. Get the full story at our sister site, Drug Delivery Business News. The post Corium touts clinical data for transdermal delivery of Alzheimer’s drug appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - July 18, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Drug-Device Combinations Food & Drug Administration (FDA) Neurological Pharmaceuticals Wall Street Beat Corium Source Type: news

Namzaric (Memantine Hydrochloride Extended-release and Donepezil Hydrochloride Capsules) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 5, 2017 Category: Drugs & Pharmacology Source Type: news

Corium ’s Corplex Donepezil demonstrates positive outcome in pilot BE trial
US-based Corium International has reported positive preliminary results from a pilot bioequivalence (BE) clinical trial of Corplex Donepezil in healthy subjects. (Source: Drug Development Technology)
Source: Drug Development Technology - May 11, 2017 Category: Pharmaceuticals Source Type: news

Study: Gene Test Needed Before Using Alzheimer's Drug'Off-Label '
Aricept is often prescribed for mild mental impairment without actual approval Source: HealthDay Related MedlinePlus Page: Alzheimer's Disease (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 7, 2017 Category: Consumer Health News Source Type: news

Study: Gene Test Needed Before Using Alzheimer's Drug'Off-Label '
TUESDAY, March 7, 2017 -- A drug used to treat Alzheimer ' s disease should not be prescribed to people with milder mental impairment without first giving them a genetic test, a new study urges. The drug is donepezil (brand name: Aricept). Donepezil... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 7, 2017 Category: Journals (General) Source Type: news

Alzheimer's drug prescribed off-label could pose risk for some
Donepezil, a medication that is approved to treat people with Alzheimer's disease, should not be prescribed for people with mild cognitive impairment without a genetic test. UCLA School of Nursing researchers discovered that for people who carry a specific genetic variation - the K-variant of butyrylcholinesterase, or BChE-K - donezpezil could accelerate cognitive decline. (Source: World Pharma News)
Source: World Pharma News - February 27, 2017 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Alzheimer's drug prescribed off-label could pose risk for some
Donepezil, a medication that is approved to treat people with Alzheimer ' s disease, should not be prescribed for people with mild cognitive impairment without a genetic test. Researchers discovered that for people who carry a specific genetic variation -- the K-variant of butyrylcholinesterase, or BChE-K -- donezpezil could accelerate cognitive decline. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 26, 2017 Category: Science Source Type: news