Assessing the impact of a novel house design on the incidence of malaria in children in rural Africa: study protocol for a household-cluster randomized controlled superiority trial
This study aims to determine whether living in a novel design house with elevated bedrooms and permeable screened walls reduces malaria, respiratory tract infections, and diarrhoea among children in rural Tanzania.Methods/study designThis is a household-randomized, controlled study in 60 villages in Mtwara, Tanzania. A total of 550 households are randomly selected, 110 of which are allocated a novel design house and 440 households continue to reside in traditional houses. A dynamic cohort of about 1650 children under 13 years will be enrolled and followed for 3 years, approximately 330 living in novel design houses and 132...
Source: Trials - June 20, 2022 Category: Research Source Type: clinical trials
Evaluating the Safety and Efficacy of the Probiotic Bifidobacterium Longum ES1 and the Post Biotic Heat-treated Bifidobacterium Longum ES1 (HT-ES1) on IBS Symptom Severity in Patients With Diarrhoea Predominant Irritable Bowel Syndrome
Condition: Irritable Bowel Syndrome With Diarrhea Interventions: Other: ES 1; Other: HT ES1; Other: Placebo Sponsor: Vedic Lifesciences Pvt. Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 21, 2022 Category: Research Source Type: clinical trials
Trial to Evaluate Diarrhoea Discontinuations at 3 Cycles in Patients With Early-stage HER2+, HR+ Breast Cancer Treated With Neratinib Plus Loperamide Versus Neratinib Dose Escalation Plus Loperamide Administered as Needed Versus Neratinib Plus Loperamide Plus Colesevelam (DIANER)
Conditions: Early-stage Breast Cancer; HER2 Positive Breast Cancer; Hormone Receptor Positive Interventions: Drug: Neratinib; Drug: Loperamide; Drug: Colesevelam Sponsors: Spanish Breast Cancer Research Group; Puma Biotechnology, Inc.; Pierre Fabre Laboratories Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2022 Category: Research Source Type: clinical trials
