Exposure to Outdoor Cold Air Beneficial for Children With Croup
TUESDAY, Aug. 1, 2023 -- A 30-minute exposure to outdoor cold air is beneficial for reducing clinical symptoms in children with croup as an adjunct to oral dexamethasone, according to a study published online Aug. 1 in Pediatrics. Johan N. Siebert,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 1, 2023 Category: Pharmaceuticals Source Type: news

Dexamethasone Best for Persistent, Recurrent Uveitic Macular Edema
THURSDAY, June 22, 2023 -- For patients with minimally active or inactive uveitis and persistent or recurrent uveitic macular edema (ME), dexamethasone is significantly better for treatment than methotrexate or ranibizumab, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 22, 2023 Category: Pharmaceuticals Source Type: news

Dexamethasone Compared to Burr-Hole Drainage for Chronic Subdural Hematoma
THURSDAY, June 15, 2023 -- For patients with chronic subdural hematoma, a 19-day tapering course of dexamethasone therapy is not noninferior to surgery with respect to functional outcomes at three months, according to a study published in the June... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 15, 2023 Category: Pharmaceuticals Source Type: news

Dexamethasone or Surgery for Chronic Subdural Hematoma?
(MedPage Today) -- Dexamethasone treatment failed to demonstrate noninferiority to surgery for chronic subdural hematoma and was associated with more complications and a greater risk of later surgery, according to results of a randomized study... (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - June 15, 2023 Category: Surgery Source Type: news

Steroid Implants Best for Improving Vision in Uveitis ME Steroid Implants Best for Improving Vision in Uveitis ME
The MERIT trial of intravitreal dexamethasone, ranibizumab, or methotrexate for persistent or recurrent macular edema after uveitis treatment found that only dexamethasone improved vision.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 13, 2023 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Perineural and Systemic Dexamethasone and Ulnar Nerve Block Perineural and Systemic Dexamethasone and Ulnar Nerve Block
What effect does the administration of perineural versus systemic dexamethasone have on the duration of ulnar nerve block?Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 13, 2023 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Janssen to Highlight Scientific Advances and Commitment to Transform Cancer Care at ASCO and EHA with More than 90 Presentations Showcasing Robust, Differentiated Portfolio and Pipeline in Hematologic Malignancies and Solid Tumors
This study evaluates an investigational combination regimen of IMBRUVICA® (ibrutinib) plus venetoclax (I+V) for newly diagnosed chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), (Abstracts #7535 and #P617, respectively).Advancing the Science of Solid Tumors Through Precision MedicineJanssen’s continued innovation in solid tumors focuses on advancing precision medicine options for patients with biomarker-driven disease who have limited targeted treatment options and moving patients into earlier lines of therapy when treatments may be more effective. Lung CancerAn oral presentation will report ...
Source: Johnson and Johnson - May 18, 2023 Category: Pharmaceuticals Tags: Innovation Source Type: news

What Causes Pulmonary Edema?
Discussion Pulmonary edema is a potentially life threatening condition due to accumulation of excess fluid in the alveolar spaces and walls of the lung. Patients show increased respiratory effort or distress (e.g. tachypnea, dyspnea or difficulty talking, use of excessory muscles, nasal flaring, tracheal tugging, etc.) and clinicians should beware signs of tiring (e.g. bradypnea and decreased effort) as the patient may be failing. Patients may have rales or rhonchi on pulmonary examination, and pallor or color changes may be noted. Blood gas analysis shows evidence of hypoxemia and often hypercapnia depending on the severi...
Source: PediatricEducation.org - May 15, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Steroid May Benefit Some With Chronic Subdural Hematoma Steroid May Benefit Some With Chronic Subdural Hematoma
Outcomes were better with surgery than with dexamethasone in this randomized trial, but results hint that the steroid might provide an alternative to surgery for some patients.Medscape Medical News (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - April 24, 2023 Category: Intensive Care Tags: Neurology & Neurosurgery News Source Type: news

Dexamethasone Still Beneficial for Some Inpatients With COVID-19
THURSDAY, April 20, 2023 -- Early administration of dexamethasone is associated with significantly reduced odds of mortality or discharge to hospice for inpatients with COVID-19 receiving supplemental oxygen or mechanical ventilation (MV) and/or... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 20, 2023 Category: Pharmaceuticals Source Type: news

Dexamethasone therapy prevents delayed neuropsychiatric sequelae after carbon monoxide poisoning: a prospective registry-based study - Kim S, Choi S, Ko Y, Lee CA, Kim GW, Moon JE, Nah S, Han S.
BACKGROUND: Delayed neuropsychiatric sequelae are major complications of carbon monoxide poisoning; carbon monoxide triggers brain oxidation and inflammation. Corticosteroids such as dexamethasone modulate neurological damage after carbon monoxide poisonin... (Source: SafetyLit)
Source: SafetyLit - February 8, 2023 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Severely ill COVID-19 patients may benefit from glucocorticoid drug
<img width="100" src="https://factor.niehs.nih.gov/sites/niehs-factor/files/styles/large/public/2020/9/feature/2-feature-glucocorticoid-drug/thumb899392.jpg?itok=Fw47BEM1" /><br /><p>Dexamethasone reduces dangerous inflammation seen late in the disease, say an NIEHS scientist and his collaborator.</p> (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - February 3, 2023 Category: Environmental Health Source Type: news

Alternative to Lenalidomide ID'd for Maintenance in Multiple Myeloma
WEDNESDAY, Feb. 1, 2023 -- For patients with newly diagnosed multiple myeloma after induction treatment and autologous stem cell transplantation, maintenance therapy with carfilzomib, lenalidomide, and dexamethasone may be better than lenalidomide... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 1, 2023 Category: Pharmaceuticals Source Type: news

Janssen Announces Unblinding of Phase 3 CARTITUDE-4 Study of CARVYKTI ® (cilta-cel) as Primary Endpoint Met in Treatment of Patients with Relapsed and Refractory Multiple Myeloma
RARITAN, New Jersey, January 27, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the Phase 3 CARTITUDE-4 study evaluating CARVYKTI® (ciltacabtagene autoleucel; cilta-cel) versus pomalidomide, bortezomib, and dexamethasone (PVd) or daratumumab, pomalidomide, and dexamethasone (DPd) for the treatment of patients with relapsed and lenalidomide-refractory multiple myeloma met its primary endpoint of significant improvement in progression-free survival (PFS) at the first pre-specified interim analysis. As a result of meeting the primary endpoint, the Independent Data Monitoring Commi...
Source: Johnson and Johnson - January 27, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Is Pulsed Steroid Riskier for COVID-19?
(MedPage Today) -- SAN FRANCISCO -- For hospitalized COVID-19 patients, pulsed methylprednisolone was not a good alternative to dexamethasone, based on the worse outcomes seen with it in a large Japanese study. Among 1,197 propensity-matched... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - January 22, 2023 Category: Infectious Diseases Source Type: news