Triplet Therapy Slows Refractory Multiple Myeloma
WEDNESDAY, Nov. 18, 2020 -- A once-weekly regimen of selinexor, bortezomib, and dexamethasone slows the progression of relapsed or refractory multiple myeloma, according to a study published in the Nov. 14 issue of The Lancet.
Sebastian Grosicki,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 18, 2020 Category: Pharmaceuticals Source Type: news
COVID-19 therapy: corticosteroids including dexamethasone and hydrocortisone, NHS England
In accordance with World Health Organization (WHO) recommendations, this letter explains that systemic corticosteroids should be used in patients with severe and critical COVID-19 disease, but not in patients with non-severe COVID-19. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 17, 2020 Category: Consumer Health News Source Type: news
Cytokine storms play a limited role in moderate-to-severe COVID-19
Rather than life-threatening hyperinflammation, most adults with moderate-to-severe COVID-19 have a suppressed viral immune response when compared to adults with another viral respiratory infection, influenza. St. Jude Children's Research Hospital and Washington University School of Medicine in St. Louis led research that suggests most COVID-19 patients are not candidates for treatment with steroids such as dexamethasone. (Source: World Pharma News)
Source: World Pharma News - November 16, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news
FDA Allows Emergency Use of Antibody Drug to Fight COVID-19
(WASHINGTON) — U.S. health officials have allowed emergency use of the first antibody drug to help the immune system fight COVID-19, an experimental approach against the virus that has killed more than 238,000 Americans.
The Food and Drug Administration on Monday cleared the experimental drug from Eli Lilly for people 12 and older with mild or moderate COVID-19 not requiring hospitalization. It’s a one-time treatment given through an IV.
The therapy is still undergoing additional testing to establish its safety and effectiveness. It is similar to a treatment President Donald Trump received after contracting the...
Source: TIME: Health - November 10, 2020 Category: Consumer Health News Authors: Matthew Perrone / AP Tags: Uncategorized COVID-19 overnight wire Source Type: news
New discovery may change how dexamethasone is prescribed for some COVID-19 patients
(DOE/Argonne National Laboratory) New insights into the way the body distributes dexamethasone could mean that patients with high blood sugar may see diminished effects. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 9, 2020 Category: International Medicine & Public Health Source Type: news
Janssen Headlines American Society of Hematology Annual Meeting With More Than 35 Presentations Highlighting Deep, Diverse Oncology Pipeline and Portfolio
RARITAN, N.J., November 5, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today more than 35 company-sponsored studies, including 10 oral presentations, will be featured at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition taking place virtually December 5-8, 2020.In multiple myeloma, highlights include Phase 1b/2 results for the B-cell maturation antigen (BCMA)-targeted chimeric antigen receptor T-cell (CAR-T) therapy ciltacabtagene autoleucel (cilta-cel); new and updated data for the anti-CD38 monoclonal antibody DARZALEX® (daratumumab) and the subcutaneous for...
Source: Johnson and Johnson - November 5, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news
U.S. Sets New Daily COVID-19 Record Amid Election Turmoil
New confirmed cases of the coronavirus in the U.S. have climbed to an all-time high of more than 86,000 per day on average, in a glimpse of the worsening crisis that lies ahead for the winner of the presidential election.
Cases and hospitalizations are setting records all around the country just as the holidays and winter approach, demonstrating the challenge that either President Donald Trump or former Vice President Joe Biden will face in the coming months.
Daily new confirmed coronavirus cases in the U.S. have surged 45% over the past two weeks, to a record 7-day average of 86,352, according to data compiled by Johns Ho...
Source: TIME: Health - November 5, 2020 Category: Consumer Health News Authors: Lindsey Tanner / AP Tags: Uncategorized COVID-19 overnight wire Source Type: news
U.S. COVID-19 Cases Are Skyrocketing, But Deaths Are Flat —So Far. These 5 Charts Explain Why
In just the last two weeks, the global daily tally for new COVID-19 cases has jumped more than 30%, according to TIME’s coronavirus tracker, which compiles data from Johns Hopkins University. The steep upward trend is driven by viral waves in Europe and the United States that started in August and mid-September, respectively. On Oct. 23, the daily case count in the U.S. reached a new record high, suggesting that this wave will be worse than the one that swept the country over the summer.
But despite this rapid uptick in cases, the daily death count in the U.S. is not yet rising at the same rate, and remains at lower ...
Source: TIME: Health - October 26, 2020 Category: Consumer Health News Authors: Emily Barone Tags: Uncategorized COVID-19 UnitedWeRise20Disaster Source Type: news
COVID-19: Dexamethasone discovery carries treatment implications
(University of Virginia Health System) A new finding about dexamethasone suggests diabetes and other factors may reduce its potentially lifesaving effectiveness for patients with severe COVID-19. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 22, 2020 Category: International Medicine & Public Health Source Type: news
Featured Review: Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis
ConclusionsFor people at higher risk, some medicines worked well to stop them from being sick after general anaesthesia. The most reliable antiemetic medicines were aprepitant, ramosetron, granisetron, dexamethasone, and ondansetron, followed by fosaprepitant and droperidol.However, the authors did not find enough reliable evidence about potential unwanted effects to rank these medicines reliably according to how well they worked.Read the full review on the Cochrane LibraryVisit the Cochrane Anaesthesia Group websiteTuesday, October 20, 2020 (Source: Cochrane News and Events)
Source: Cochrane News and Events - October 15, 2020 Category: Information Technology Authors: Rachel Klabunde Source Type: news
Could Trump Spread Coronavirus at Town Hall? Likely Not, Experts Say
While questions have surrounded the timing and severity of the president ’s illness, health experts said he was unlikely to infect people at Thursday’s town hall event on NBC. (Source: NYT Health)
Source: NYT Health - October 15, 2020 Category: Consumer Health News Authors: Apoorva Mandavilli Tags: Trump, Donald J United States Politics and Government Presidential Election of 2020 White House Coronavirus Outbreak (2020) Coronavirus (2019-nCoV) NBC News Television Dexamethasone (Drug) your-feed-science Coronavirus Risks and Safety C Source Type: news
For How Long Will President Trump Be Immune to the Coronavirus?
A unique treatment course may have blunted his body ’s production of antibodies, scientists warn. (Source: NYT Health)
Source: NYT Health - October 14, 2020 Category: Consumer Health News Authors: Apoorva Mandavilli Tags: your-feed-science Antibodies White House Coronavirus Outbreak (2020) Dexamethasone (Drug) Coronavirus (2019-nCoV) Steroids Regeneron Pharmaceuticals Inc Biden, Joseph R Jr Trump, Donald J Presidential Election of 2020 Source Type: news
