Analyses of Adherence Strategies and Data Sets from CALERIE to Explore Behavioral and Psychosocial Aspects of Sustained Caloric Restriction in Humans (R01 - Clinical Trial Not Allowed)
Funding Opportunity PA-18-825 from the NIH Guide for Grants and Contracts. The National Institute on Aging (NIA) invites applications for research projects (R01) involving secondary analyses of data in the Computerized Tracking System (CTS) database from the CALERIE (Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy) trial to explore behavioral and psychosocial aspects of sustained caloric restriction (CR) in humans, including the translation of the CR adherence strategies used in the trial to promote healthy behaviors, especially for the prevention of weight gain with age. CALERIE was the first...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 8, 2018 Category: Research Source Type: funding

Exploratory Analyses of Adherence Strategies and Data Sets from CALERIE to Investigate Behavioral and Psychosocial Aspects of Sustained Caloric Restriction in Humans (R21 - Clinical Trial Not Allowed)
Funding Opportunity PA-18-826 from the NIH Guide for Grants and Contracts. The National Institute on Aging (NIA) invites applications for new exploratory research projects (R21) involving secondary analyses of data in the Computerized Tracking System (CTS) database from the CALERIE (Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy) trial to explore behavioral and psychosocial aspects of sustained caloric restriction (CR) in humans, including the translation of the CR adherence strategies used in the trial to promote healthy behaviors, especially for the prevention of weight gain with age. CALER...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 8, 2018 Category: Research Source Type: funding

Open Mike Perspective: Healthy Skepticism when Focusing Solely on Surrogate Endpoints in Clinical Research
I recently wrote an essay for the NIH’s Science, Health, and Public Trust series to encourage a healthy bit of skepticism about clinical studies that solely involve surrogate end-points (e.g. changes in “biomarkers” like blood cholesterol levels or findings on an electrocardiogram). To make my point, I described experiences with a well-known cardiovascular trial — one that focused on the risk of sudden death among heart attack survivors. I encourage readers in this essay to not just assume that treating a surrogate endpoint will automatically treat the underlying condition. Sometimes it does.  But sometimes it...
Source: NIH Extramural Nexus - May 3, 2018 Category: Research Authors: Mike Lauer Tags: blog Open Mike Clinical Trials innovation Perspectives Source Type: funding

Research Supplements to Promote Data Sharing in Cancer Epidemiology Studies (Admin Supp Clinical Trial Not Allowed)
Funding Opportunity PA-18-748 from the NIH Guide for Grants and Contracts. The purpose of the administrative supplement is to provide support for NIH-funded investigators to prepare and deposit individual-level data from cancer epidemiology studies into NIH/NCI-supported, controlled-access databases including the Cancer Epidemiology Data Repository (CEDR) and the database of Genotypes and Phenotypes (dbGaP). Sharing of research data will accelerate scientific discovery and increase opportunities for collaboration to provide new clues to cancer etiology, determine risk factors, and improve cancer survivorship. (Source: N...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 10, 2018 Category: Research Source Type: funding

National Network of Libraries of Medicine Middle Atlantic Region Grants
Funding for projects in the middle Atlantic region that improve health literacy; increase the ability of the general public to find and use health information; or improve health professionals ’ access to, awareness of, and skills for locating high quality biomedical and health information. Geographic coverage: Delaware, New Jersey, New York, and Pennsylvania -- National Library of Medicine (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - March 21, 2018 Category: American Health Source Type: funding

Genomic Centers for Infectious Diseases (U19 Clinical Trial Not Allowed)
Funding Opportunity RFA-AI-18-004 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to support Genomic Centers for Infectious Diseases (GCID) to promote broad use and expand the application of genomics technologies and computational analysis to understand infectious diseases, with an emphasis on pathogens, their interaction with the host and microbiome, and to aid in the development of novel genomics-based tools to diagnose, prevent and treat infectious diseases. The GCID will support innovative technology development in all aspects of genomics, including the use of synthetic and genome edit...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 15, 2018 Category: Research Source Type: funding

Health Information Outreach Award: Southeastern/Atlantic Region
Funding for projects in the Southeastern/Atlantic region that improve health literacy; increase the ability of the general public to find and use health information; or improve health professionals ’ access to, awareness of, and skills for locating high quality biomedical and health information. Geographic coverage: Alabama, District of Columbia, Georgia, Florida, Maryland, Mississippi, North Carolina, Puerto Rico, South Carolina, Tennessee, Virginia, West Virginia, and the U.S. Virgin Islan ds. -- National Library of Medicine (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - March 2, 2018 Category: American Health Source Type: funding

Lewy Body Dementia Center Without Walls (CWOW) (U54 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-18-024 from the NIH Guide for Grants and Contracts. This FOA invites applications that will systematically and comprehensively characterize alpha-synuclein and amyloid-beta subspecies present in human Lewy Body Dementia (LBD) post-mortem brain tissue, identify toxic subspecies and potential mechanisms of toxicity, and characterize any interactions between the proteins that may contribute to increased toxicity and/or explain selective vulnerabilities of cells/circuits. Applications are required to include at least 3 hypothesis-driven projects that address these goals, an administrative core, an...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 9, 2018 Category: Research Source Type: funding

Resource Implementations for Data Intensive Research in the Social, Behavioral and Economic Sciences (RIDIR)
Full Proposal Deadline Date: February 28, 2018 Program Guidelines: NSF 18-517As part of NSF’s Harnessing the Data Revolution (HDR), the Directorate for Social, Behavioral and Economic Sciences (SBE) seeks to develop user-friendly large-scale next-generation data resources and relevant analytic techniques to advance fundamental research in SBE areas of study. Successful proposals will, within the financial resources provided by the award, construct such databases and/or relevant analytic techniques and produce a finished product that will enable new types of ...More at https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=...
Source: NSF Upcoming Due Dates - January 29, 2018 Category: Science Source Type: funding

NextGen Tissue Chip Testing Centers: Validating Microphysiological Systems (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-TR-18-006 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for NextGen Tissue Chip Testing Center(s) (NextGen TCTC) that will provide resources and infrastructure for the validation of tissue chips being developed as part of the NIH Tissue Chip (TC) for Drug Screening Program or NIH Microphysiological Systems (MPS) Program. The MPS program supports a consortium of investigators developing accurate cellular and organ microsystems representative of human physiology for the evaluation of drug efficacy and toxicity (RFA-RM-11-022; RFA-TR-16...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 20, 2017 Category: Research Source Type: funding

When a Country is Open, Do They Have Strong Science Too?
As no scientist is an island, the overall scientific enterprise grows stronger when people work together. But, an interesting question emerges from this concept for us to explore: how can we quantify the effect of collaboration on productivity and impact on science? In the October 5 issue of Nature, Caroline Wagner, Ph.D. of the Ohio State University and Koen Jonker’s, Ph.D. of the European Commission Joint Research Center published an interesting analysis of the association of a country’s “openness” and its scientific productivity. The authors assembled data from the Scopus database—a wealth of information on ci...
Source: NIH Extramural Nexus - December 11, 2017 Category: Research Authors: Mike Lauer Tags: blog Open Mike bibliometrics publications Source Type: funding

mHealth Tools for Individuals with Chronic Conditions to Promote Effective Patient-Provider Communication, Adherence to Treatment and Self-Management (R21 Clinical Trial Optional)
Funding Opportunity PA-18-389 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to stimulate research utilizing Mobile Health (mHealth) tools aimed at the improvement of effective patientprovider communication, adherence to treatment and self-management of chronic diseases. With the rapid expansion of cellular networks and substantial advancements in Smartphone technologies, it is now possible - and affordable - to transmit patient data digitally from remote areas to specialists in urban areas, receive real-time feedback, and capture that consultation in a database. These mHealth tools, ther...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 21, 2017 Category: Research Source Type: funding

mHealth Tools for Individuals with Chronic Conditions to Promote Effective Patient-Provider Communication, Adherence to Treatment and Self-Management (R01 Clinical Trial Optional)
Funding Opportunity PA-18-386 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to stimulate research utilizing Mobile Health (mHealth) tools aimed at the improvement of effective patientprovider communication, adherence to treatment and self-management of chronic diseases. With the rapid expansion of cellular networks and substantial advancements in Smartphone technologies, it is now possible - and affordable - to transmit patient data digitally from remote areas to specialists in urban areas, receive real-time feedback, and capture that consultation in a database. These mHealth tools, ther...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 21, 2017 Category: Research Source Type: funding

Continuing steps to Ensuring Credibility of NIH Research: Selecting Journals with Credible Practices
The scientific community is paying increasing attention to the quality practices of journals and publishers. NIH recently released a Guide notice (NOT-OD-18-011) to encourage authors to publish in journals that do not undermine the credibility, impact, and accuracy of their research findings. This notice aims to raise awareness about practices like changing publication fees without notice, lacking transparency in publication procedures, misrepresenting editorial boards, and/or using suspicious peer review. This may not be a big problem for NIH-funded publications now; our colleagues Jennifer Marill, Kathryn Funk, and Jerry...
Source: NIH Extramural Nexus - November 8, 2017 Category: Research Authors: Mike Lauer Tags: blog Open Mike Peer review publications rigor Source Type: funding

Research Grants Using the Resources from the Osteoarthritis Initiative (OAI) (R21) - Clinical Trial Not Allowed
Funding Opportunity PA-18-408 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications for research awards that are focused on the use of the Osteoarthritis Initiative (OAI) database, clinical data and images. This FOA seeks to expand the use of these resources by investigators in the broader research community. The publication of this FOA to the research community indicates to investigators and peer reviewers the importance that the NIAMS and others have placed on the use of the OAI resources. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 26, 2017 Category: Research Source Type: funding