Clot Wars contd. - More than 2,000 Lawsuits Over Pradaxa Bleeding Risks, Boehringer Confirms
Boehringer Ingelheim, manufacturer of the blood-thinner Pradaxa (dabigatran), has confirmed that it faces more 2,000 lawsuits in the United States alleging that the drug causes severe and fatal bleeding.The company’s confirmation came after the German newspaper Handelsblatt reported the number. Boehringer said that the company has to weigh the risk of known side effects against the drug’s life saving potential, according to Reuters. “We are certain that we can show in the legal cases that we have worked very carefully and responsibly in research, development and marketing of Pradaxa,” the German drug maker said in ...
Source: PharmaGossip - February 13, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs
More Than a Number
A 68-year-old woman with a history of schizophrenia, severe coronary artery disease, hypertension, and type 2 diabetes mellitus was found in her bed minimally responsive by staff at the group home where she lived. She had been discharged from the hospital two days earlier with a diagnosis of segmental pulmonary embolism and on Coumadin anticoagulation. Lower extremity Doppler ultrasounds were negative for deep vein thrombosis during that hospitalization.
EMS brought her to the emergency department, and had intubated for airway protection. She was febrile, tachycardic, and hypotensive, and had a hemoglobin of 4 g/dL. An ...
Source: Spontaneous Circulation - February 12, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
More Than a Number
A 68-year-old woman with a history of schizophrenia, severe coronary artery disease, hypertension, and type 2 diabetes mellitus was found in her bed minimally responsive by staff at the group home where she lived. She had been discharged from the hospital two days earlier with a diagnosis of segmental pulmonary embolism and on Coumadin anticoagulation. Lower extremity Doppler ultrasounds were negative for deep vein thrombosis during that hospitalization.
EMS brought her to the emergency department, and had intubated for airway protection. She was febrile, tachycardic, and hypotensive, and had a hemoglobin of 4 g/dL. A...
Source: Spontaneous Circulation - February 12, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Popular Blood-thinner Manufacturer Didn’t Want Internal Research Made Public
Boehringer Ingelheim, the manufacturer of the blood-thinning drug Pradaxa, was concerned that releasing the results of an internal research paper on the drug would damage drug sales, records recently made public show. The company was so worried about the results of the study that some employees pressured the author to revise it, and the company recommended it be thrown out, according to a recent report by the New York Times.Records recently made public by a federal judge in Illinois presiding over thousands of lawsuits against the maker of Pradaxa, including emails, internal memos, and presentations, centered on the resear...
Source: Medical Hemostat - February 7, 2014 Category: Technology Consultants Authors: hemostatguy at gmail.com (hemostat guy) Source Type: blogs
99226 CPT ® Code Description, Progress Notes, RVU, Distribution.
This 99226 CPT ® lecture reviews the procedure code definition, progress note examples, distribution and RVU values for this new since 2011 subsequent observation care evaluation and management (E/M) code. CPT stands for Current Procedural Terminology. CPT ® 99226 is the highest (level 3) subsequent observation care code in this family of codes that also includes CPT® codes99224 and99225. All three codes are part of the Healthcare Common Procedure Coding System (HCPCS). Observation care is considered outpatient care. A patient is considered outpatient until inpatient admission to a healthcare fa...
Source: The Happy Hospitalist - February 5, 2014 Category: Internal Medicine Authors: The Happy Hospitalist Source Type: blogs
99226 CPT® Code Description, Progress Notes, RVU, Distribution.
This 99226 CPT® lecture reviews the procedure code definition, progress note examples, distribution and RVU values for this new since 2011 subsequent observation care evaluation and management (E/M) code. CPT stands for Current Procedural Terminology. CPT® 99226 is the highest (level 3) subsequent observation care code in this family of codes that also includes CPT® codes 99224 and 99225. All three codes are part of the Healthcare Common Procedure Coding System (HCPCS). Observation care is considered outpatient care. A patient is considered outpatient until inpatient admission to a healthca...
Source: The Happy Hospitalist - February 5, 2014 Category: Internists and Doctors of Medicine Authors: Tamer Mahrous Source Type: blogs
99226 CPT ® Code Description, Progress Notes, RVU, Distribution.
This 99226 CPT ® lecture reviews the procedure code definition, progress note examples, distribution and RVU values for this new since 2011 subsequent observation care evaluation and management (E/M) code. CPT stands for Current Procedural Terminology. CPT ® 99226 is the highest (level 3) subsequent observation care code in this family of codes that also includes CPT® codes99224 and99225. All three codes are part of the Healthcare Common Procedure Coding System (HCPCS). Observation care is considered outpatient care. A patient is considered outpatient until inpatient admission to a healthcare fa...
Source: The Happy Hospitalist - February 5, 2014 Category: Internal Medicine Authors: The Happy Hospitalist Source Type: blogs
DTC Melee–a-Trois: Pradaxa, Xarelto, and Eliquis. Women Only Marginally Involved.
(Source: Pharma Marketing Blog)
Source: Pharma Marketing Blog - January 24, 2014 Category: Pharma Commentators Tags: AFib BMS Boehringer Ingelheim DTC Advertising Eliquis Janssen Pradaxa warfarin Xarelto Source Type: blogs
Doctors play an important role in improving US healthcare woes
Elisabeth Rosenthal, a reporter with the New York Times, is doing American doctors a favor. Her series, Paying Till it Hurts, is forcing us to face our role in the US healthcare problem. That’s a good thing, because, as it goes in the practice of Medicine, the first step to achieving good outcomes is identifying the problems.
Ms. Rosenthal’s most recent piece, Patients’ Costs Skyrocket; Specialists’ Incomes Soar, published today on the front page of the Sunday Times, aimed its scalpel on the lucrative specialty of Dermatology. But one mustn’t focus too much on the skin, there are ample areas of healthcare in ...
Source: Dr John M - January 19, 2014 Category: Cardiology Authors: Dr John Source Type: blogs
New post up on Cardiology Medscape: Lessons learned from the failure of Renal denervation for high blood pressure
Most people come by it honestly. They eat too much, move too little, skimp on sleep, take on too much stress and then succumb to buying larger clothes. The word we use in medicine is insidious.
High blood pressure (hypertension – HTN) is one of the leading cardiovascular problems of this time. Some have called treating HTN the holy grail of medicine. Think about why this may be. The human heart contracts 100,000 times per day. Each beat delivers a pressure load to the thousands of arteries in the body. Over days, weeks, months, years and decades, small elevations of high pressure can have devastating wear and tear ef...
Source: Dr John M - January 16, 2014 Category: Cardiology Authors: Dr John Source Type: blogs
FDA Plans New Safety Assessment Of Dabigatran (Pradaxa)
Since the approval of dabigatran (Pradaxa, Boehringer Ingelheim) in Europe in 2008 and in the US in 2010 there have been persistent and lingering concerns about the drug’s safety. Now the FDA plans to perform a large new assessment of the drug compared to warfarin. n December 30 the FDA posted a request for public comment on a proposed protocol of the study, which it describes as “a one-time assessment of selected safety outcomes in adults with atrial fibrillation who are new users of dabigatran or warfarin.” … Click here to read the full post on Forbes. (Source: CardioBrief)
Source: CardioBrief - January 3, 2014 Category: Cardiology Authors: Larry Husten Tags: Heart Rhythms People, Places & Events Prevention, Epidemiology & Outcomes anticoagulants dabigatran FDA warfarin Source Type: blogs
Buy Codeine Online for cough, fever, pain and diarrhea
If you are staying anywhere in UK then there’s good news for you. You can buy codeine from the internet and this is really quite simple. You just got to have a computer at home from where you can opt for online buying option and in this way you can get the desired medication and in this case codeine at your door steps. Also, the online deal would be a bit cheaper as compared to the offline option. There are many problems that can be treated with the help of codeine. Just go through the information given below and you will understand how useful codeine is.
Codeine is useful for many health issues
Lots of studies have been...
Source: Mental Nurse - December 26, 2013 Category: Nurses Authors: Iqcguest Tags: Health amily planning cough drug interactions fever pain and diarrhea Source Type: blogs
EMA Journal December 2013
This report, from the Emergency Care Improvement & Innovation Clinical Network, describes a project that used a multimodal approach, grounded in quality and safety theory, to improve consistency in clinical practice, minimise risks and strengthen clinical governance arrangements for paediatric sedation across a number of Victorian EDs. Key activities addressed clinical governance, risk assessment and procedure documentation, training and credentialing of clinicians, and clinical audit of key quality and safety measures. This multi-modal implementation strategy supported by an evidence-based programme and resources ena...
Source: Life in the Fast Lane - December 23, 2013 Category: Emergency Medicine Doctors Authors: Mike Cadogan Tags: Education eLearning EMA Emergency Medicine Featured Journal burden of GP patients Burnout chest pain EMA Journal emergency medicine australasia NOACs oral anticoagulants paediatric procedural sedation Saline therapy Source Type: blogs
New post up at Medscape Cardiology: Are novel anticoagulants better than warfarin?
For the prevention of stroke in atrial fibrillation, the novel anticoagulant drugs dabigatran (Pradaxa, Boehringer Ingelheim), rivaroxaban (Xarelto, Bayer Pharma/Janssen Pharmaceuticals), apixaban (Eliquis, Pfizer/Bristol-Myers Squibb), and edoxaban (Lixiana, Daiichi-Sankyo) have been sold as both superior and more convenient than warfarin.
But is this true? More than 60,000 patients have been enrolled in randomized controlled clinical trials. Recently, two meta-analyses (studies that combine trials) have been published. That’s a bunch of data.
I had originally set out to explain how these meta-analyses had once and ...
Source: Dr John M - December 20, 2013 Category: Cardiology Authors: Dr John Source Type: blogs
