Funtabulously Frivolous Friday Five 156
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 155 Question 1 What is the story behind the Cochrane logo? + Reveal the Funtabulous Answer expand(document.getElementById('ddet1929929766'));expand(document.getElementById('ddetlink1929929766')) The forest plot within the logo shows one of the first meta analyses done by Cochrane. It was showing the benefit of corticosteroids given to women who are about to give birth prematurely. Despite several trials showing the...
Source: Life in the Fast Lane - August 26, 2016 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five cochrane logo fava beans G6PD deficiency Hannibal methaemoglobinaemia scabies scrivener's palsy seven year itch writers palsy Source Type: blogs

Anorectal Procedures: Thrombosed Hemorrhoids
We are going to get up close and personal this month to talk about hemorrhoids. You should be familiar with these painful offenders because half to two-thirds of people between 45 and 65 will suffer from their cruelty. (Am Surg 2009;75[8]:635.) Patients may seek emergency department care if they experience bleeding or severe pain from hemorrhoids.Hemorrhoids are highly vascular structures that are round or oval in shape. They arise from the rectal and anal canal, and sometimes appear around the anus itself. It is important to note that hemorrhoids do not have arteries and veins but special blood vessels called sinusoid...
Source: The Procedural Pause - August 1, 2016 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

The Wages of Sin - a Small Illustration of How Executives Can Personally Profit from Bad Corporate Behavior in Health Care
Conclusions < /b > < br / > < br / > So this case appears to be a step forward, in that not all the people who apparently authorized, directed, or implemented the bad behavior could escape any negative consequences. & nbsp; Keep in mind, however, that no one above the two convicted executives, no one at Johnson and Johnson who decided to acquire Acclarent, and let it continue its previous activities, seemed to suffer any negative consequences. & nbsp; How much money those executives might have received in response to the revenues that the new subsidiary brought in is unknown. < br / > < br / > In conclusion, this case show...
Source: Health Care Renewal - July 27, 2016 Category: Health Management Tags: adulterated devices crime Ethicon impunity Johnson and Johnson legal settlements medical devices perverse incentives Source Type: blogs

Research and Reviews in the Fastlane 136
Welcome to the 136th edition of Research and Reviews in the Fastlane. R&R in the Fastlane is a free resource that harnesses the power of social media to allow some of the best and brightest emergency medicine and critical care clinicians from all over the world tell us what they think is worth reading from the published literature. This edition contains 6 recommended reads. The R&R Editorial Team includes Jeremy Fried, Nudrat Rashid, Soren Rudolph, Justin Morgenstern, Anand Swaminathan and, of course, Chris Nickson. Find more R&R in the Fastlane reviews in the R&R Archive, read more...
Source: Life in the Fast Lane - May 26, 2016 Category: Emergency Medicine Authors: Nudrat Rashid Tags: Education Emergency Medicine Intensive Care Pre-hospital / Retrieval Renal Resuscitation R&R in the FASTLANE recommendations research and reviews Source Type: blogs

Research and Reviews in the Fastlane 135
Welcome to the 135th edition of Research and Reviews in the Fastlane. R&R in the Fastlane is a free resource that harnesses the power of social media to allow some of the best and brightest emergency medicine and critical care clinicians from all over the world tell us what they think is worth reading from the published literature. This edition contains 6 recommended reads. The R&R Editorial Team includes Jeremy Fried, Nudrat Rashid, Soren Rudolph, Justin Morgenstern, Anand Swaminathan and, of course, Chris Nickson. Find more R&R in the Fastlane reviews in the R&R Archive, read more about the R&R ...
Source: Life in the Fast Lane - May 18, 2016 Category: Emergency Medicine Authors: Nudrat Rashid Tags: Disaster Education Emergency Medicine Intensive Care Neurology Pediatrics Pre-hospital / Retrieval Respiratory Resuscitation critical care R&R in the FASTLANE recommendations research and reviews Source Type: blogs

Pomalyst, Darzalex, and Corticosteroids
Weekly Infusion Number 6: Blood draw, doctor visit, pre-medications, and Darzalex, about 6 hours total. I took 20 mg dexamethasone last night, as part of the Pomalyst regimen, and received 100 mg of prednisone IV before the Darzalex, as part of that regimen. As before no problems, no infusion reactions. This is getting boring. Boring is good. I love boring. (Source: Myeloma Hope)
Source: Myeloma Hope - May 10, 2016 Category: Cancer & Oncology Tags: corticosteroids daratumumab Darzalex dexamethasone pomalidomide Pomalyst prednisone Source Type: blogs

Pomalyst, Darzalex, and Corticosteroids
Weekly Infusion Number 6:  Blood draw, doctor visit, pre-medications, and Darzalex, about 6 hours total. I took 20 mg dexamethasone last night, as part of the Pomalyst regimen, and received 100 mg of prednisone IV before the Darzalex, as part of that regimen. As before no problems, no infusion reactions.  This is getting boring. Boring is good.  I love boring. (Source: Myeloma Hope)
Source: Myeloma Hope - May 10, 2016 Category: Cancer & Oncology Tags: corticosteroids daratumumab Darzalex dexamethasone pomalidomide Pomalyst prednisone Source Type: blogs

LITFL Review 228
Welcome to the 227th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chuck of FOAM. The Most Fair Dinkum Ripper Beauts of the Week Another awesome post on Dr Smith’s ECG blog. A must for anyone who sees patients with chest pain. [CC] The Best of #FOAMed Emergency Medicine An awesome review from Ken Milne and our own Salim Rezaie talking nerdy about a recent paper on HE...
Source: Life in the Fast Lane - April 24, 2016 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs

A Nefarious Character with an Agenda
Every new advanced nurse practitioner, physician assistant, or resident gets his fair share of complex emergency department procedures during training. Seasoned providers, however, are just as excited to place a central line in a septic patient, LP a "rule-out meningitis," or swiftly fix a nursemaid's elbow.This month we hope to remind you of a few sweet and satisfying procedures that take only moments to do. Your skill in completing these procedures is imperative. Not only will you amaze your patient, but you'll shorten your door to dispo-time.The StyeThe stye is a nefarious character with an agenda. It starts o...
Source: The Procedural Pause - February 1, 2016 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

DM / DNB Cardiology Entrance Mock Test 8
This study found that though it is often associated with coronary artery disease (CAD), it can also occur in those without significant CAD. It was not specifically associated with disease of right coronary artery disease. This cardioinhibitory response may be a manifestation of the Bezold-Jarisch reflex. Bezold-Jarisch reflex inhibits sympathetic activity (sympathetic withdrawal) and increases parasympathetic activity, resulting in bradycardia, which may be associated with vasodilatation, nausea and hypotension. Bezold-Jarisch has been described in the setting of inferior wall infarction and coronary angiography. Origin...
Source: Cardiophile MD - January 26, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ Cardiology X-ray Featured Source Type: blogs

Have you heard of henoch-schonlein purpura?
I sure don’t remember this condition in nursing school! Henoch-Schonlein Purpura (HSP) is a disease involving inflammation of small blood vessels. It most commonly occurs in children. The inflammation causes blood vessels in the skin, intestines, kidneys and joints to start leaking. The main symptom is a rash with numerous small bruises, which have a raised appearance over the legs or buttocks. Although HSP can affect people at any age, most cases occur in children between the ages of 2 and 11. It is more common in boys than girls. Adults with HSP are more likely to have more severe disease compared to children. HSP usua...
Source: Nursing Comments - October 18, 2015 Category: Nursing Authors: Stephanie Jewett, RN Tags: Advice/Education Caregiving General Public Nursing/Nursing Students Patients/Specific Diseases blood in urine children diarrhea HENOCH-SCHONLEIN PURPURA inflammation of blood vessels joint pain joint swelling kidney disease loss Source Type: blogs

Inhaled corticosteroids for neonatal BPD: The jury is still out...
Inhaled corticosteroids for neonatal BPD: The jury is still out via Now@NEJM Posted on infosnack. (Source: Kidney Notes)
Source: Kidney Notes - October 14, 2015 Category: Urology & Nephrology Authors: Joshua Schwimmer Source Type: blogs

Praluent, the Next Expensive "Game Changer," Blockbuster," "New Hope," - But Not Yet Shown to Benefit Patients
ConclusionsThe NEJM study was accompanied by an editorial by Stone and Lloyd-Jones(2) which documented that drugs previously shown to lower cholesterol were never proved to do any good for patients, and concluded,it would be premature to endorse these drugs for widespread use before the ongoing randomized trials, appropriately powered for primary end-point analysis and safety assessment, are available. After an FDA advisory committee recommended approval of aliromucab and another PCSK9 inhibitor in June, 2015, John Mandrola entitled a Medscape article,Dear FDA: Resist the Urge on PCSK9 DrugsHis reasons included lack o...
Source: Health Care Renewal - August 5, 2015 Category: Health Management Tags: aliromucab evidence-based medicine health care prices manipulating clinical research PCSK9 inhibitor Praluent Regeneron Sanofi-Aventis Source Type: blogs