Core protocol for the adaptive Platform Trial In COVID-19 Vaccine priming and BOOsting (PICOBOO)
DiscussionPICOBOO is the first adaptive platform trial evaluating different COVID-19 priming and booster vaccination strategies in Australia, and one of the few established internationally, that is designed to generate high-quality evidence to inform immunisation practice and policy. The modular, hierarchical protocol structure is intended to standardise outcomes, endpoints, data collection and other study processes for nested substudies included in the trial platform and to minimise duplication. It is anticipated that this flexible trial structure will enable investigators to respond with agility to new research questions...
Source: Trials - March 18, 2023 Category: Research Source Type: clinical trials

Hydrogen-Oxygen Generator With Nebulizer for Adjuvant Treatment of Novel Coronavirus Disease 2019 (COVID-19)
Conditions:   Covid19;   Hydrogen-oxygen Gas;   AMS-H-03 Interventions:   Device: Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03;   Device: OLO-1 Medical Molecular Sieve Oxygen Generator Sponsor:   Guangzhou Institute of Respiratory Disease Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2023 Category: Research Source Type: clinical trials

Lifestyle Changes by the COVID-19 (Coronavirus Disease 2019) Pandemic in Children With Developmental Delays
Conditions:   Lifestyle-related Condition;   COVID-19 Pandemic;   Children With Developmental Delays Intervention:   Other: lifestyle questionnaire Sponsor:   Taipei Medical University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2023 Category: Research Source Type: clinical trials

Hydrogen-Oxygen Generator With Nebulizer for Adjuvant Treatment of Novel Coronavirus Disease 2019 (COVID-19)
Conditions:   Covid19;   Hydrogen-oxygen Gas;   AMS-H-03 Interventions:   Device: Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03;   Device: OLO-1 Medical Molecular Sieve Oxygen Generator Sponsor:   Guangzhou Institute of Respiratory Disease Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2023 Category: Research Source Type: clinical trials

Lifestyle Changes by the COVID-19 (Coronavirus Disease 2019) Pandemic in Children With Developmental Delays
Conditions:   Lifestyle-related Condition;   COVID-19 Pandemic;   Children With Developmental Delays Intervention:   Other: lifestyle questionnaire Sponsor:   Taipei Medical University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2023 Category: Research Source Type: clinical trials

Hydrogen-Oxygen Generator With Nebulizer for Adjuvant Treatment of Novel Coronavirus Disease 2019 (COVID-19)
Conditions:   Covid19;   Hydrogen-oxygen Gas;   AMS-H-03 Interventions:   Device: Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03;   Device: OLO-1 Medical Molecular Sieve Oxygen Generator Sponsor:   Guangzhou Institute of Respiratory Disease Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2023 Category: Research Source Type: clinical trials