Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation
Conditions: Heart Failure; Inflammation Interventions: Drug: Low Dose Colchicine; Drug: Placebo Sponsors: University of Texas Southwestern Medical Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials

Effect of Colchicine on Perioperative Anti-inflammatory Organ Injury in Cardiac Surgery
Conditions: Inflammatory Response; Cardiac Disease Interventions: Drug: Colchicine 0.5 MG; Drug: Placebo Sponsors: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School; First Affiliated Hospital of Zhejiang University; Jinan Central Hospital; The First People ' s Hospital of Changzhou; Xinhua hospital of ILi in Kazakhstan automomous district; First Affiliated Hospital of Harbin Medical University; Yangzhou University; Renji Hospital Affiliated to The Shanghai Jiao Tong University Medical School Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 6, 2023 Category: Research Source Type: clinical trials

This Study is Two-center, Prospective, Randomized, Open-label, Controlled, Investigator-sponsored Study That Aims to Investigate the Efficacy of Low-dose Colchicine in Preventing Recurrent Stroke in the Patients With Acute Atherothrombotic Minor-to-moderate Ischemic Stroke During Hospitalization
Conditions: Ischemic Stroke Interventions: Drug: Colchicine; Drug: Clopidogrel Sponsors: Mikhail Zykov Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 26, 2023 Category: Research Source Type: clinical trials

Efficacy of Colchicine in Preventing Recurrent Stroke in the Patients With Acute Atherothrombotic Ischemic Stroke During Hospitalization
Conditions: Ischemic Stroke Interventions: Drug: Colchicine; Drug: Clopidogrel Sponsors: Mikhail Zykov Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 26, 2023 Category: Research Source Type: clinical trials

Colchicine in Belgium in Patients With Coronary Artery Disease After Percutaneous Coronary Intervention
Conditions: Coronary Artery Disease Interventions: Drug: Colchicine 0.5 MG Oral Tablet; Drug: Placebo Sponsors: AZ Sint-Jan AV; University Hospital, Ghent; Belgium Health Care Knowledge Centre Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 23, 2023 Category: Research Source Type: clinical trials

Anti-inflammatory Therapy for Recurrent In-stent Restenosis
Conditions: In-stent Restenosis Interventions: Drug: Colchicine; Drug: Prednisone; Drug: Aspirin; Drug: P2Y12 Receptor Antagonist; Drug: Lipid-lowering drug Sponsors: Fu Wai Hospital, Beijing, China Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 19, 2023 Category: Research Source Type: clinical trials

Different Doses of Colchicine on hsCRP
Conditions: Coronary Artery Disease; Percutaneous Coronary Intervention Interventions: Drug: Colchicine 0.5 MG; Drug: Colchicine 0.375 MG; Drug: Colchicine 0.25 MG; Drug: Placebo Sponsors: Wuhan Union Hospital, China Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2023 Category: Research Source Type: clinical trials

The COLchicine HEART Failure PRESERVED Trial (COLHEART-PRESERVED)
Conditions: Heart Failure With Preserved Ejection Fraction Interventions: Drug: Colchicine; Drug: Placebo Sponsors: Tor Biering-S ørensen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2023 Category: Research Source Type: clinical trials

Empagliflozin and colchicine in patients with reduced left ventricular ejection fraction following ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: a study protocol for a randomized, double-blinded, three-arm parallel-group, controlled trial
DiscussionThe present study will be the first trial to evaluate the efficacy and safety of early treatment with the combination of standard-dose empagliflozin and colchicine as well as high-dose empagliflozin in non-diabetic patients with reduced left ventricular ejection fraction following ST-elevation myocardial infarction. The results of this research will represent a significant step forward in the treatment of patients with acute myocardial infarction.Trial registrationClinical trial ID: IRCT20111206008307N39. Registration date: 27 October 2022.Graphical Abstract (Source: Trials)
Source: Trials - October 6, 2023 Category: Research Source Type: clinical trials

Prednisolone Versus Colchicine for Acute Gout in Primary Care (COPAGO): protocol for a two-arm multicentre, pragmatic, prospective, randomized, double-blind, controlled clinical trial of prednisolone and colchicine for non-inferiority with a parallel group design
DiscussionThis trial will provide evidence on the effectiveness of pain reduction and side effects of colchicine and prednisolone in acute gout in primary care.Trial registrationClinicalTrials.gov Identifier: NCT05698680 first posted on January 26, 2023 (retrospectively registered). URL of trial registry record:https://clinicaltrials.gov/study/NCT05698680 (Source: Trials)
Source: Trials - October 5, 2023 Category: Research Source Type: clinical trials

COlchicine iN Circulating Inflammatory Markers After StrokE (CONCISE)
Conditions: Ischemic Stroke; Atherosclerosis Interventions: Drug: Colchicine 0.5 MG Sponsors: University College Dublin; Mater Misericordiae University Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 2, 2023 Category: Research Source Type: clinical trials

The Effect of Colchicine on Inflammation in ACS Patients
Conditions:   Acute Coronary Syndrome;   STEMI Intervention:   Drug: Colchicine Tablets Sponsor:   Ain Shams University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 26, 2023 Category: Research Source Type: clinical trials

The Effect of Colchicine on Inflammation in ACS Patients
Conditions: Acute Coronary Syndrome; STEMI Interventions: Drug: Colchicine Tablets Sponsors: Ain Shams University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 26, 2023 Category: Research Source Type: clinical trials