Effect of atorvastatin calcium plus clopidogrel in the treatment of patients with transient ischemic attacks and its effect on blood lipids and platelets
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - January 10, 2024 Category: Neuroscience Authors: Maocheng BianFei ZhongJian WanEmergency and Critical Care Medicine, Shanghai Pudong New Area People ’s Hospital, Shanghai, China Source Type: research

Evaluation of potentially inappropriate medications for the elderly according to beers, STOPP, START, and Chinese criteria
Conclusion: Polypharmacy and PIMs were common in our study, and the risk of PIMs correlated with polypharmacy. Application of the Beers, Chinese, STOPP, and START criteria is a useful tool for detecting PIM use. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 3, 2024 Category: Drugs & Pharmacology Source Type: research

Low RBC counts predict high on-treatment platelet reactivity in patients undergoing percutaneous coronary intervention and treated with clopidogrel
J Biomed Res. 2023 Dec 15:87-91. doi: 10.7555/JBR.37.20230035. Online ahead of print.NO ABSTRACTPMID:38164104 | DOI:10.7555/JBR.37.20230035 (Source: Biomed Res)
Source: Biomed Res - January 2, 2024 Category: Research Authors: Qian Gu Qin Wang Rui Hua Wenhao Zhang Jianzhen Teng Jiazheng Ma Zhou Dong Xiaoxuan Gong Chunjian Li Source Type: research

Low RBC counts predict high on-treatment platelet reactivity in patients undergoing percutaneous coronary intervention and treated with clopidogrel
J Biomed Res. 2023 Dec 15:87-91. doi: 10.7555/JBR.37.20230035. Online ahead of print.NO ABSTRACTPMID:38164104 | DOI:10.7555/JBR.37.20230035 (Source: Biomed Res)
Source: Biomed Res - January 2, 2024 Category: Research Authors: Qian Gu Qin Wang Rui Hua Wenhao Zhang Jianzhen Teng Jiazheng Ma Zhou Dong Xiaoxuan Gong Chunjian Li Source Type: research

Clopidogrel
(Source: Reactions Weekly)
Source: Reactions Weekly - January 1, 2024 Category: Drugs & Pharmacology Source Type: research

LA-GEM: imputation of gene expression with incorporation of Local Ancestry
Pac Symp Biocomput. 2024;29:341-358.ABSTRACTGene imputation and TWAS have become a staple in the genomics medicine discovery space; helping to identify genes whose regulation effects may contribute to disease susceptibility. However, the cohorts on which these methods are built are overwhelmingly of European Ancestry. This means that the unique regulatory variation that exist in non-European populations, specifically African Ancestry populations, may not be included in the current models. Moreover, African Americans are an admixed population, with a mix of European and African segments within their genome. No gene imputati...
Source: Pacific Symposium on Biocomputing - December 31, 2023 Category: Bioinformatics Authors: Mrinal Mishra Layan Nahlawi Yizhen Zhong Tanima De Guang Yang Cristina Alarcon Minoli A Perera Source Type: research

LA-GEM: imputation of gene expression with incorporation of Local Ancestry
Pac Symp Biocomput. 2024;29:341-358.ABSTRACTGene imputation and TWAS have become a staple in the genomics medicine discovery space; helping to identify genes whose regulation effects may contribute to disease susceptibility. However, the cohorts on which these methods are built are overwhelmingly of European Ancestry. This means that the unique regulatory variation that exist in non-European populations, specifically African Ancestry populations, may not be included in the current models. Moreover, African Americans are an admixed population, with a mix of European and African segments within their genome. No gene imputati...
Source: Pacific Symposium on Biocomputing - December 31, 2023 Category: Bioinformatics Authors: Mrinal Mishra Layan Nahlawi Yizhen Zhong Tanima De Guang Yang Cristina Alarcon Minoli A Perera Source Type: research

An overview of the utility of prasugrel hydrochloride as a treatment option for ischemic stroke
Expert Rev Neurother. 2023 Dec 30:1-6. doi: 10.1080/14737175.2023.2295420. Online ahead of print.ABSTRACTINTRODUCTION: Prasugrel, a potent P2Y12 receptor inhibitor, is not currently recommended in patients with stroke due to a higher rate of recurrent stroke. Prasugrel was associated with comparable efficacy to clopidogrel in reducing the risk of ischemic stroke in a recent phase III study.AREAS COVERED: The authors provide an overview of the potential role of prasugrel in the management of ischemic stroke. The authors searched PUBMED, MEDLINE, and clinicaltrials.org and recently presented trials at the conferences for cli...
Source: Expert Review of Neurotherapeutics - December 30, 2023 Category: Neurology Authors: Udaya S Tantry Sahib Singh Kevin P Bliden Paul A Gurbel William Ashley Source Type: research