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Identifying disrupted biological factors and patient-tailored interventions for chronic fatigue in adolescents and young adults with Q-Fever Fatigue Syndrome, Chronic Fatigue Syndrome and Juvenile Idiopathic Arthritis (QFS-study): study protocol for a randomized controlled trial with single-subject experimental case series design
DiscussionThe QFS-study is a comprehensive study exploring disrupted biological factors and patient-tailored lifestyle advices as intervention in adolescent and young adults with QFS and similar manifestations of chronic fatigue. Practical or operational issues are expected during the study, but can be overcome through innovative study design, statistical approaches, and recruitment strategies. Ultimately, the study aims to contribute to biological research and (personalized) treatment in QFS and similar manifestations of chronic fatigue.Trial registrationTrialNL8789. Registered July 21, 2020. (Source: Trials)
Source: Trials - August 19, 2022 Category: Research Source Type: clinical trials

Melatonin and Zinc Administration on Cardinal Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Conditions:   Chronic Fatigue Syndrome;   Myalgic Encephalomyelitis Interventions:   Dietary Supplement: melatonin plus zinc;   Other: isomaltose and magnesium stearate Sponsors:   Laboratorios Viñas, S.A.;   Laboratorio Echevarne;   Hospital Vall d'Hebron Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 12, 2022 Category: Research Source Type: clinical trials

Biofeedback and Hydrogen Water as Treatments for Chronic Fatigue Syndrome
Condition:   Chronic Fatigue Syndrome Interventions:   Behavioral: Heart Rhythm Biofeedback;   Dietary Supplement: Hydrogen Water;   Combination Product: Combined treatment: Heart rhythm biofeedback plus hydrogen water Sponsors:   Stony Brook University;   Natural Wellness Now Health Products Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 31, 2022 Category: Research Source Type: clinical trials