A Phase 2 Open-label Study to Assess the Safety and Immunogenicity of an Alum-adjuvanted Chikungunya Virus-like Particle Vaccine (PXVX0317) in Prior Recipients of Other Alphavirus Vaccines Versus Alphavirus na ïve Controls.
Condition: Chikungunya Intervention: Biological: Chikungunya Sponsors: PaxVax, Inc.; Walter Reed Army Institute of Research (WRAIR) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 20, 2019 Category: Research Source Type: clinical trials
A Phase 2 Open-label Study to Assess the Safety and Immunogenicity of an Alum-adjuvanted Chikungunya Virus-like Particle Vaccine (PXVX0317) in Prior Recipients of Other Alphavirus Vaccines
Condition: Chikungunya Intervention: Biological: Chikungunya Sponsors: PaxVax, Inc.; Walter Reed Army Institute of Research (WRAIR) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 20, 2019 Category: Research Source Type: clinical trials
Efficacy of the In2Care ® auto-dissemination device for reducing dengue transmission: study protocol for a parallel, two-armed cluster randomised trial in the Philippines
DiscussionFor decades, it has been commonly accepted that an integrated approach to mosquito control is required. The World Health Organization (WHO) Global Strategic Framework for Integrated Vector Management recommends a range of interventions, in combination, to increase control impact to reduce transmission. This efficacy trial of the first commercial product using the AD approach will be informative in assessing the general utility of AD in reducing not only adult vector densities but, more importantly, reducing the incidence of dengue. The AD technique may complement source reduction and larviciding campaigns by more...
Source: Trials - May 13, 2019 Category: Research Source Type: clinical trials
Phase 2 Study of a Chikungunya Vaccine in Previously Exposed Adults
Condition: Chikungunya Virus Infection Interventions: Biological: MV-CHIK; Other: Placebo Sponsors: Themis Bioscience GmbH; Walter Reed Army Institute of Research (WRAIR) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2019 Category: Research Source Type: clinical trials
