An International, Multicentre, Open-label Randomised Phase III Trial to Evaluate the Benefit of Adding Adjuvant Durvalumab After Neoadjuvant Chemotherapy Plus Durvalumab in Patients With Stage IIB-IIIB (N2) Resectable NSCLC
Conditions: Non Small Cell Lung Cancer Interventions: Drug: Adjuvant durvalumab Sponsors: ETOP IBCSG Partners Foundation; AstraZeneca AG Switzerland Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

Early Prediction and Warning for Cardiotoxicity Due to Anthracycline-Based Breast Cancer Chemotherapy
Conditions: Breast Cancer Interventions: Device: Echocardiography Sponsors: First Hospital of China Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

Biobanking Upper Gastrointestinal Tumors to Evaluate Response (BURGER With BACON)
Conditions: GastroEsophageal Cancer Interventions: Drug: Immune checkpoint inhibitor (ICI) or chemotherapy alone Sponsors: Duke University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer
Conditions: Triple Negative Breast Cancer Interventions: Drug: SKB264; Drug: Paclitaxel; Drug: Nab-paclitaxel; Drug: Capecitabine; Drug: Eribulin; Drug: Carboplatin Sponsors: Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients With Early-stage, Operable, Non-small Cell Lung Cancer.
Conditions: Non Small Cell Lung Cancer Interventions: Drug: Adjuvant durvalumab Sponsors: ETOP IBCSG Partners Foundation; AstraZeneca AG Switzerland Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

A Study of Camrelizumab Combined With Chemotherapy ± Thalidomide in First-line Treatment of Patients With Advanced Non-small Cell Lung Cancer (NSCLC)
Conditions: Lung Cancer; Camrelizumab Interventions: Drug: Camrelizumab + chemotherapy+Thalidomide; Drug: Camrelizumab + chemotherapy+placebo Sponsors: Tongji University; Shanghai Pulmonary Hospital, Shanghai, China Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

Effect of Adjuvant Chemotherapy Cycles on Patients With Node-negative Gastric Cancer Following Neoadjuvant Chemotherapy
Conditions: Locally Advanced Gastric Cancer Interventions: Other: surgery Sponsors: Fujian Medical University Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

A Comparative Study of the Treatment of Real-world Patients With Clear Cell Carcinoma of the Ovary
Conditions: Ovarian Clear Cell Carcinoma Interventions: Drug: physician ' s choice of chemotherapy; Drug: immune checkpoint inhibitor based therapy Sponsors: Tongji Hospital; Wuhan Union Hospital, China; Henan Cancer Hospital; Qilu Hospital of Shandong University; Hubei Cancer Hospital; Anhui Provincial Cancer Hospital; Peking University Cancer Hospital& Institute; Hunan Province Tumor Hospital; First Affiliated Hospital of Suzhou Medical College; Shandong Tumor Hospital; Chongqing University Cancer Hospital; First Affiliated Hospital of Zhongshan Medical University; Peking University Shenzhen Hospital Not yet recruiting (...
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

Administration of Hyperthermic Intraperitoneal Chemotherapy in the General Ward
Conditions: Epithelial Ovarian Cancer Interventions: Procedure: China Hyperthermic Intraperitoneal Chemotherapy(C-HIPEC) Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; Shenshan Medical Center, Memorial Hospital of Sun Yat-sen University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

Safety and Efficacy of NRT6008 in Patients With Unresectable Locally Advanced Pancreatic Cancer (LAPC)
Conditions: Unresectable Pancreatic Cancer Interventions: Drug: NRT6008 Injection + Systematic chemotherapy Sponsors: Chengdu New Radiomedicine Technology Co. LTD. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

Effect of Sarcopenia on the Occurrence of Toxicity Related to Anti-cancer Treatments
Conditions: Sarcopenia; Oncology; Physical Inactivity; Toxicity Due to Chemotherapy Interventions: Diagnostic Test: Sarcopenia diagnostic test Sponsors: Centre Hospitalier Metropole Savoie; Universit é Savoie Mont Blanc Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials

DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients With Metastatic Colorectal Cancer
Conditions: Older Patients; Colorectal Cancer; Metastatic Cancer; Candidates for Palliative Chemotherapy Interventions: Drug: Doublet Chemotherapy, Standard Dose (100%); Drug: Doublet Chemotherapy, Dose-reduced (75%); Drug: Monotherapy, Standard Dose (100%); Drug: Monotherapy, Dose-reduced (75%) Sponsors: Leiden University Medical Center; Dutch Colorectal Cancer Group; Stichting Darmkanker Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials

Tolerability and Efficacy of Adjuvant T-DM1 in Patients With HER2 Positive Breast Cancer After Incomplete Pathological Response to Neoadjuvant Chemotherapy Including Anti-HER2 Agents. Real-world Multicenter Retrospective-prospective Study
Conditions: Breast Cancer Interventions: Drug: T-DM1 adjuvant Sponsors: Regina Elena Cancer Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2024 Category: Research Source Type: clinical trials

Evaluation of Metastatic Disease and Oncological Treatment in Patients With Colon Cancer Using Zebra Fish Avatars
Conditions: Colon Cancer Interventions: Drug: Chemotherapy drug Sponsors: University Hospital, Linkoeping Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2024 Category: Research Source Type: clinical trials

Breast Cancer - Navigate - Prospective Cohort
Conditions: Breast Cancer; Quality of Life; Chemotherapy Interventions: Behavioral: BC-Navigate Sponsors: Northwestern University; The Chrysalis Initiative Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2024 Category: Research Source Type: clinical trials