Pharnext drug shows promise in neurological disease with no treatment
(Reuters) - Using technology gleaned from the mapping of the human genome, privately held French drug developer Pharnext SAS is a step closer to providing a treatment for a rare neurological disorder called Charcot-Marie-Tooth (CMT) disease, for which no pharmaceutical therapy exists. (Source: Reuters: Health)
Source: Reuters: Health - December 18, 2014 Category: Consumer Health News Tags: healthNews Source Type: news
Recent Advances in Charcot-Marie-Tooth DiseaseRecent Advances in Charcot-Marie-Tooth Disease
Charcot-Marie-Tooth is the most prevalent hereditary neuromuscular disorder. What progress has been made in understanding its genetic basis, and what's the latest on treatment? Current Opinion in Neurology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 28, 2014 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news
'I planned my own funeral': Misdiagnosed mum celebrated her new lease of life
KARIN RODGERS thought she'd 'drawn the lucky straw' when doctors told her a Charcot Marie Tooth disease - rather than a rare, fatal condition - was causing her movement problems (Source: Daily Express - Health)
Source: Daily Express - Health - September 15, 2014 Category: Consumer Health News Source Type: news
Potential therapy for incurable Charcot-Marie-Tooth disease found
A potential new treatment approach for hereditary neurological disorder, the incurable Charcot-Marie-Tooth disease, has been found by researchers. Patients with Charcot-Marie-Tooth disease type 1A harbour an extra copy of the PMP22 gene which leads to the overproduction of the peripheral myelin protein 22 (PMP22), a key component of myelin. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 27, 2014 Category: Science Source Type: news
Potential therapy for incurable Charcot-Marie-Tooth disease
(Max-Planck-Gesellschaft) Researchers discover a new treatment approach for this hereditary neurological disorder. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 27, 2014 Category: Biology Source Type: news
Postural stabilization and balance assessment in Charcot-Marie-Tooth 1A subjects - Lencioni T, Rabuffetti M, Piscosquito G, Pareyson D, Aiello A, Di Sipio E, Padua L, Stra F, Ferrarin M.
The aim of the present study was to assess postural stabilization skill in adult subjects affected by Charcot-Marie-Tooth disease (CMT) type 1A. For this purpose ground reaction force (GRF) was measured by means of a piezoelectric force platform during the... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - August 8, 2014 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Obstructive Sleep Apnea, RLS, and Charcot-Marie-ToothObstructive Sleep Apnea, RLS, and Charcot-Marie-Tooth
Fatigue is a major complaint of Charcot-Marie-Tooth patients. Could sleep apnea and restless leg syndrome be contributors? Journal of Neurology, Neurosurgery, and Psychiatry (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 7, 2014 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news
Ascorbic Acid in Charcot-Marie-Tooth-1AAscorbic Acid in Charcot-Marie-Tooth-1A
It seems to work in mice, but is it futile to pursue the use of ascorbic acid to reduce neuropathy in humans? Medscape Neurology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 16, 2013 Category: Consumer Health News Tags: Neurology & Neurosurgery Viewpoint Source Type: news
Zebrafish Study Offers Hope For Patients With Charcot Marie Tooth Disease
Scientists from the University of Sheffield have paved the way for new treatments for a common genetic disorder thanks to pioneering research on zebrafish - an animal capable of mending its own heart. Charcot Marie Tooth disease (CMT) is the most common genetic disorder affecting the nervous system. More than 20,000 people in the UK suffer from CMT, which typically causes progressive weakness and long-term pain in the feet, leading to walking difficulties. There is currently no cure for CMT... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 28, 2013 Category: Consumer Health News Tags: Genetics Source Type: news
Whole Genome Or Exome Sequencing: An Individual Insight
Focusing on parts rather than the whole, when it comes to genome sequencing, might be extremely useful, finds research in BioMed Central's open access journal Genome Medicine. The research compares several sequencing technologies in the same individual with Charcot-Marie-Tooth disease (CMT), and shows that sequencing the coding regions alone at high depth of coverage can identify the genetic variation behind this disease, and was also able to resolve previous ambiguities... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 27, 2013 Category: Consumer Health News Tags: Genetics Source Type: news
Genome vs. exome: Which works best?
Baylor College of Medicine researchers discovered that they could identify the genetic variation behind the genetic disease Charcot-Marie-Tooth disease by sequencing the exome. (Source: Baylor College of Medicine News)
Source: Baylor College of Medicine News - June 27, 2013 Category: Universities & Medical Training Source Type: news
Ascorbic Acid Ruled Out for Nerve Disorder (CME/CE)
(MedPage Today) -- Despite promising results in mice, high doses of ascorbic acid appear to have no benefit in people with Charcot-Marie-Tooth disease, an inherited neurodegenerative disorder, researchers reported. (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - June 24, 2013 Category: Neurology Source Type: news
How Turning Down Synthesis Of A Protein Improves Nerve, Muscle Function In Common Neuropathy
A potential new treatment strategy for patients with Charcot-Marie-Tooth disease is on the horizon, thanks to research by neuroscientists now at the University at Buffalo's Hunter James Kelly Research Institute and their colleagues in Italy and England. The institute is the research arm of the Hunter's Hope Foundation, established in 1997 by Jim Kelly, Buffalo Bills Hall of Fame quarterback, and his wife, Jill, after their infant son Hunter was diagnosed with Krabbe Leukodystrophy, an inherited fatal disorder of the nervous system. Hunter died in 2005 at the age of eight... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 30, 2013 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news
Hitting 'reset' in protein synthesis restores myelination
(University at Buffalo) A potential new treatment strategy for patients with Charcot-Marie-Tooth disease is on the horizon, thanks to research by neuroscientists now at the University at Buffalo's Hunter James Kelly Research Institute and their colleagues in Italy and England. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 26, 2013 Category: Global & Universal Source Type: news
Charcot-Marie-Tooth DiseasesCharcot-Marie-Tooth Diseases
It's now understood that Charcot-Marie-Tooth isn't one disease, but several peripheral neuropathies arising from mutations in over 40 different genes. Does each variation have a distinct mechanism? Brain (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 4, 2013 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news
