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Phase 3 Keytruda, Chemotherapy Mesothelioma Trial Shows Promising Results
Pharmaceutical company Merck says use of its immunotherapy drug Keytruda in conjunction with chemotherapy increases the survival rate for people with advanced pleural mesothelioma, according to the latest results of a phase 3 clinical trial. The results were announced in June at the annual meeting of the American Society of Clinical Oncology. They showed Merck’s use of the anti-PD-1 treatment combined with chemotherapy reduced the patient’s risk of death by 21%. Clinical trial results of the multimodal treatment using immunotherapy and chemo also showed a median overall survival of 17.3 months in comparison...
Source: Asbestos and Mesothelioma News - June 26, 2023 Category: Environmental Health Authors: Fran Mannino Tags: Clinical Trials/Research/Emerging Treatments Mesothelioma Source Type: news

Bicuspid Aortic Valves and Aortopathy Cluster Among Close Relatives
(MedPage Today) -- Diagnoses of bicuspid aortic valve (BAV), thoracic aortic aneurysm, and thoracic aortic dissection appeared to run in families extending beyond first-degree relatives, according to the largest pedigree-based study on the subject... (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - June 15, 2023 Category: Surgery Source Type: news

COVID-19 Can Cause New Cholesterol Problems. What to Know
Not long after the start of the global coronavirus pandemic, it was apparent that many people infected with SARS-CoV-2 were developing persistent and, in some cases, debilitating health problems. Now known widely as post-Covid syndrome or Long COVID, the most common symptoms of this condition are fatigue, attention problems, headaches, muscle or joint pain, and weakness. But those are just the start. Medical researchers have also linked SARS-CoV-2 to lingering complications in multiple organs and systems, and some recent work has found that new-onset cholesterol problems may be an under-recognized but common complication o...
Source: TIME: Health - May 30, 2023 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized healthscienceclimate heart health Source Type: news

Bariatric Surgery Tied to Less Medication Use Over 15 or More Years
FRIDAY, May 26, 2023 -- Patients undergoing bariatric surgery for obesity use fewer lipid-lowering, cardiovascular, and antidiabetic medications over the long term versus patients with obesity not undergoing surgery, according to a study published... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 26, 2023 Category: Pharmaceuticals Source Type: news

Delaney, Mooney, Murray and Tripoli Win PitchFest Competition
Amy Delaney, BSN, RN, Emily Mooney, BSN, RN, Christina Murray, BSN, RN, and Maryssa Tripoli, BSN, RN, of the Thoracic Surgery Step-Down Unit on Braunwald Tower 11ABD, won the Estrellita& Yousuf Karsh Nursing Scholars Day ’s PitchFest competition for (Source: BWH News)
Source: BWH News - May 26, 2023 Category: Hospital Management Source Type: news

Obesity-Related Medication Use Remains Low After Bariatric Surgery
(MedPage Today) -- Fewer patients with obesity used lipid-lowering, cardiovascular, or antidiabetic drugs after bariatric surgery compared with matched patients who did not have surgery for morbid obesity, a population-based cohort study in Sweden... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - May 25, 2023 Category: Cardiology Source Type: news

First Phase 3 TREMFYA ® (guselkumab) Data in Inflammatory Bowel Disease Show Positive Induction Results Among Patients with Moderately to Severely Active Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, May 9, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new efficacy and safety data from the Phase 3 QUASAR Induction Study evaluating the investigational use of TREMFYA® (guselkumab) in adults with moderately to severely active ulcerative colitis (UC)a who had an inadequate response or intolerance to conventionalb and/or advanced therapies.1,c The data show statistically significant and clinically meaningful improvements across symptomatic and histo-endoscopic outcome measures.1 Safety data were also consistent with the known safety profile of TREMFYA in ...
Source: Johnson and Johnson - May 9, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Pre-CABG Statins a Dud; Peak Home BP; Patch vs Multi-Electrode Rhythm Monitors
(MedPage Today) -- High-dose statin loading before coronary artery bypass grafting (CABG) surgery did not pan out as a strategy to prevent major adverse cardiovascular events (MACE), a German randomized trial showed. (European Heart Journal) The... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - April 25, 2023 Category: Cardiology Source Type: news

Atul Gawande on the Importance of Palliative Care
(MedPage Today) -- In this video, Jeremy Faust, MD, editor-in-chief of MedPage Today, chats with author and surgeon Atul Gawande, MD, MPH, about his New York Times bestselling book, Being Mortal: Medicine and What Matters in the End. The two also... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - April 25, 2023 Category: Cardiology Source Type: news

The Worst Redo Option After TAVR?
(MedPage Today) -- For the rising number of patients needing aortic reintervention, transcatheter aortic valve replacement (TAVR) explantation carried the highest mortality risk, two registry analyses affirmed. In Society of Thoracic Surgeons... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - April 24, 2023 Category: Cardiology Source Type: news

How is Osgood-Schlatter Apophysitis Treated?
Discussion An apopysis is a secondary ossification center located at the tendinous insertion into a bone. Site irritation is called apophysitis and several proposed causes include genetics, rapid growth, trauma (compression or traction), anatomical differences and diet. Whatever the etiological factors, it causes pain. Examples include Sever’s disease of the calcaneus. Anterior knee pain is a common presenting problem in the pediatric age group, and the differential diagnosis is broad. Trauma, infection, tumors, and referred pain need to be considered but soft tissue problems tend to predominate if not a traumatic ca...
Source: PediatricEducation.org - April 17, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Update on IMBRUVICA ® (ibrutinib) U.S. Accelerated Approvals for Mantle Cell Lymphoma and Marginal Zone Lymphoma Indications
HORSHAM, Pa., April 6, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson, in collaboration with its alliance partner, Pharmacyclics, an AbbVie Company, announced today the intent to voluntarily withdraw the U.S. indications for IMBRUVICA® (ibrutinib) for the treatment of patients with mantle cell lymphoma (MCL) who have received at least one prior therapy, and for the treatment of patients with marginal zone lymphoma (MZL) who require systemic therapy and have received at least one prior anti-CD20-based therapy. This decision was made in consultation with the U.S. Food and Drug Administration (FDA), c...
Source: Johnson and Johnson - April 6, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Nigeria: Over 80,000 Nigerians Require Heart Surgeries Every Year - Experts
[Daily Trust] The Association of Cardiovascular and Thoracic Surgeons of Nigeria (ACTSON) says over 80, 000 people in Nigeria require heart surgery ever year. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 3, 2023 Category: African Health Source Type: news

The healthspan revolution: how to live a long, strong and happy life
Dr Peter Attia is an expert on longevity and preventative medicine. He explains how sleep, weight training and other incremental changes can make us much more resilientTwenty years ago, Peter Attia was working as a trainee surgeon at Johns Hopkins hospital in Baltimore, where he saved countless people facing what he calls “fast death”. “I trained in a very, very violent city,” he tells me. “We were probably averaging 15 or 16 people a day getting shot or stabbed. And, you know, that’s when surgeons can save your life. We’re really good at that.”What got to him, he says, were the people he treated who were i...
Source: Guardian Unlimited Science - March 28, 2023 Category: Science Authors: John Harris Tags: Health & wellbeing Life and style Medicine Gene editing Genetics Science Biology Society Chris Hemsworth Fitness Sleep Source Type: news

Entresto for Pre-Heart Failure; Afib and Dementia; DIY 12-Lead ECG for Patients
(MedPage Today) -- Days of greater local ambient ozone pollution coincided with excess hospital admissions for cardiovascular disease in China. (European Heart Journal) FDA and CDC officials sent a letter to Florida surgeon general Joseph Ladapo... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - March 14, 2023 Category: Cardiology Source Type: news