A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors
Conditions: Pediatric Tumor of CNS; Pediatric Tumor of Brain; Diffuse Midline Glioma, H3 K27M-Mutant; Pediatric Tumor of Brain Stem; Pineocytoma; Choroid Plexus Carcinoma, Childhood; Spinal Cord Tumor; High Grade Glioma Interventions: Drug: NEO100 Sponsors: Neonc Technologies, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials
Determining Postoperative Recovery and the Impact of Adverse Events in Neurosurgery Based on Self-reported, App-based Longitudinal Assessment - a Collaborative Observational Research Project
Conditions: Disc Disease; Instabilities Lumbar; Brain Tumor; Aneurysm Interventions: Other: OP-Tracker App Sponsors: Cantonal Hospital of St. Gallen Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 8, 2024 Category: Research Source Type: clinical trials
Development of Therapeutic Approaches Modulating Molecular Targets Implicated on Cancer Stem Cell-related Aggressiveness
Conditions: Glioblastoma; Glioma; Glioma Glioblastoma Multiforme Interventions: Other: cell isolation from tumor biopsies and biomarker investigation Sponsors: Fondazione IRCCS Ca ' Granda, Ospedale Maggiore Policlinico Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 5, 2024 Category: Research Source Type: clinical trials
Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
Conditions: Astrocytoma; Glioma; Recurrent Glioblastoma Interventions: Radiation: Radiation Therapy Sponsors: National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 3, 2024 Category: Research Source Type: clinical trials
A Vaccine (Neoantigen-Targeted ppDC) for the Treatment of H3 G34-mutant Diffuse Hemispheric Glioma
Conditions: Diffuse Hemispheric Glioma, H3 G34-Mutant Interventions: Procedure: Biospecimen Collection; Biological: Dendritic Cell Therapy; Procedure: Leukapheresis; Procedure: Magnetic Resonance Imaging; Drug: Poly ICLC Sponsors: Jonsson Comprehensive Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 2, 2024 Category: Research Source Type: clinical trials
Eye Movement Desensitization and Reprocessing Group Treatment for Caregivers of Pediatric Brain Tumor Patients
Conditions: Caregiver Burden Interventions: Other: Eye Movement Desensitization and Reprocessing Integrative Group Treatment Protocol; Other: Treatment As Usual Sponsors: IRCCS Eugenio Medea Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 1, 2024 Category: Research Source Type: clinical trials
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
Conditions: High Grade Glioma; Diffuse Intrinsic Pontine Glioma; Anaplastic Astrocytoma; Infant Type Hemispheric Glioma; Glioblastoma; Glioblastoma Multiforme; WHO Grade III Glioma; WHO Grade IV Glioma; Diffuse Midline Glioma, H3K27-altered Interventions: Drug: Lorlatinib; Drug: Lorlatinib with chemotherapy1; Drug: Lorlatinib with chemotherapy 2; Drug: Lorlatinib post Radiation Sponsors: Nationwide Children ' s Hospital; Pfizer Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 27, 2024 Category: Research Source Type: clinical trials
Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)
Conditions: Glioblastoma Multiforme; Glioblastoma; Glioma; Brain Tumor; Neoplasms; Neoplasms, Nerve Tissue Interventions: Device: NaviFUS System; Drug: Lumason; Drug: Bevacizumab Sponsors: NaviFUS Corporation; NaviFUS US LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 26, 2024 Category: Research Source Type: clinical trials
Effect of Electroacupuncture Combined With Paclitaxel Clinical Efficacy of Patients With Recurrence of High-grade Glioma
Conditions: Glioma Interventions: Drug: Temozolomide （TMZ） injection or oral administration; Drug: Albumin-Bound Paclitaxel(ABX) intravenous drip; Device: Specific mode electroacupuncture stimulation(SMES) intervention Sponsors: The Third Affiliated hospital of Zhejiang Chinese Medical University; Zhejiang University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 26, 2024 Category: Research Source Type: clinical trials
Improving Social Cognition and Social Behaviour in Various Brain Disorders
Conditions: Stroke; Multiple Sclerosis; Brain Tumor Interventions: Behavioral: Treatment social cognition and emotion regulation (T-ScEmo) Sponsors: University Medical Center Groningen Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 26, 2024 Category: Research Source Type: clinical trials
Application of Cognitive Training Based on Remind Strategy in Glioma Patients With Cognitive Impairment
Conditions: Glioma Interventions: Other: Individual cognitive rehabilitation training based on Remind strategy was given Sponsors: YuanYuan Ma Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials
A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors
Conditions: Oncology; MEK Mutation; RAF Gene Mutation; Ras (KRAS or NRAS) Gene Mutation; Melanoma; NSCLC; Glioma; Solid Tumor, Adult; MAPK Pathway Gene Mutation Interventions: Drug: NST-628 Sponsors: Nested Therapeutics, Inc Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials
Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors
Conditions: Brain Neoplasms Interventions: Procedure: Intracranial Catheter Placement; Procedure: Lumbar Puncture; Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Computed Tomography Sponsors: Mayo Clinic Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 21, 2024 Category: Research Source Type: clinical trials
Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and Gliomas
Conditions: Glioma, Malignant; Embryonal Tumor; Medulloblastoma; Ependymoma Interventions: Diagnostic Test: Tissue, blood, cerebrospinal-spinal fluid Sponsors: University Hospital Regensburg Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 21, 2024 Category: Research Source Type: clinical trials
Genetic and Molecular Characterization of Nervous System Lesions
Conditions: Brain Tumor; Brain Lesion (General) Interventions: Genetic: Prospective Biological Collection; Genetic: Retrospective Biological Collection Sponsors: Assistance Publique - H ôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2024 Category: Research Source Type: clinical trials
