Effect of negative pressure wound therapy after surgical removal of deep-seated high-malignant soft tissue sarcomas of the extremities and trunk wall —study protocol for a randomized controlled trial
This study did not apply for external funding.DiscussionMany new medical devices and technical solutions are currently being introduced, and even though some documentation regarding the use of NPWT, e.g., in joint replacement surgery exist, it is also important to seek documentation for this treatment principle in STS surgery.Trial registrationRegistered atClinicalTrials.gov NCT04960332 and approved on 11 July 2021 (Source: Trials)
Source: Trials - June 18, 2022 Category: Research Source Type: clinical trials
Efficacy of active hexose correlated compound on survival of patients with resectable/borderline resectable pancreatic cancer: a study protocol for a double-blind randomized phase II study
DiscussionAHCC is expected to function as a supportive food in patients with pancreatic ductal adenocarcinoma, to reduce the proportion of severe adverse events related to neoadjuvant chemotherapy, and to increase the completion proportion of multimodal treatments, resulting in improved survival.Trial registrationThe trial protocol has been registered in the protocol registration system at the Japan Registry of Clinical Trials (Trial ID:jRCTs051200029). At the time of the submission of this paper (October 2020), the protocol version is 2.0. The completion date is estimated to be November 2024. (Source: Trials)
Source: Trials - February 12, 2022 Category: Research Source Type: clinical trials
Randomized phase II study of gemcitabine and S-1 combination therapy versus gemcitabine and nanoparticle albumin-bound paclitaxel combination therapy as neoadjuvant chemotherapy for resectable/borderline resectable pancreatic ductal adenocarcinoma (PDAC-GS/GA-rP2, CSGO-HBP-015)
This study is the first randomized phase II study comparing GS combination therapy with GA combination therapy as NAC for localized pancreatic cancer.Trial registrationUMIN Clinical Trials RegistryUMIN000021484. This trial began in April 2016. (Source: Trials)
Source: Trials - August 26, 2021 Category: Research Source Type: clinical trials
Comparing Vacuum-Assisted Percutaneous Excision to Open Surgical Excision for Borderline or High-Risk Breast Lesions
Conditions: Breast Fibroadenoma; Atypical Ductal Hyperplasia; Atypical Lobular Hyperplasia; Lobular Carcinoma in Situ; Flat Epithelial Atypia; Phyllodes; Fibroadenoma; Phyllodes Breast Tumor; Radial Scar; Breast Papilloma; Complex Sclerosing Papillary Lesion of the Breast Interventions: Procedure: Vacuum-assisted percutaneous excision; Procedure: Open surgical excision Sponsor: Lawson Health Research Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2019 Category: Research Source Type: clinical trials
