Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.ABSTRACTDutasteride was potentially proposed to control chronic pain by Toll-Like Receptor 4 (TLR4) inhibition through its effect on TLR4 expression, Myeloid differentiation primary response 88 (MyD88), Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), secretory Interleukin-1β (IL-1β), and nitric oxide (NO) in the Lipopolysaccharides (LPS)-stimulated U-87 MG cell line. Human astrocytoma U-87 MG cell line was cultured and incubated with 10 μg/mL of LPS for 24 hours to create a neuro-inflammation model, using t...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.ABSTRACTDutasteride was potentially proposed to control chronic pain by Toll-Like Receptor 4 (TLR4) inhibition through its effect on TLR4 expression, Myeloid differentiation primary response 88 (MyD88), Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), secretory Interleukin-1β (IL-1β), and nitric oxide (NO) in the Lipopolysaccharides (LPS)-stimulated U-87 MG cell line. Human astrocytoma U-87 MG cell line was cultured and incubated with 10 μg/mL of LPS for 24 hours to create a neuro-inflammation model, using t...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.ABSTRACTDutasteride was potentially proposed to control chronic pain by Toll-Like Receptor 4 (TLR4) inhibition through its effect on TLR4 expression, Myeloid differentiation primary response 88 (MyD88), Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), secretory Interleukin-1β (IL-1β), and nitric oxide (NO) in the Lipopolysaccharides (LPS)-stimulated U-87 MG cell line. Human astrocytoma U-87 MG cell line was cultured and incubated with 10 μg/mL of LPS for 24 hours to create a neuro-inflammation model, using t...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.ABSTRACTDutasteride was potentially proposed to control chronic pain by Toll-Like Receptor 4 (TLR4) inhibition through its effect on TLR4 expression, Myeloid differentiation primary response 88 (MyD88), Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), secretory Interleukin-1β (IL-1β), and nitric oxide (NO) in the Lipopolysaccharides (LPS)-stimulated U-87 MG cell line. Human astrocytoma U-87 MG cell line was cultured and incubated with 10 μg/mL of LPS for 24 hours to create a neuro-inflammation model, using t...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.ABSTRACTDutasteride was potentially proposed to control chronic pain by Toll-Like Receptor 4 (TLR4) inhibition through its effect on TLR4 expression, Myeloid differentiation primary response 88 (MyD88), Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), secretory Interleukin-1β (IL-1β), and nitric oxide (NO) in the Lipopolysaccharides (LPS)-stimulated U-87 MG cell line. Human astrocytoma U-87 MG cell line was cultured and incubated with 10 μg/mL of LPS for 24 hours to create a neuro-inflammation model, using t...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.ABSTRACTDutasteride was potentially proposed to control chronic pain by Toll-Like Receptor 4 (TLR4) inhibition through its effect on TLR4 expression, Myeloid differentiation primary response 88 (MyD88), Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), secretory Interleukin-1β (IL-1β), and nitric oxide (NO) in the Lipopolysaccharides (LPS)-stimulated U-87 MG cell line. Human astrocytoma U-87 MG cell line was cultured and incubated with 10 μg/mL of LPS for 24 hours to create a neuro-inflammation model, using t...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.ABSTRACTDutasteride was potentially proposed to control chronic pain by Toll-Like Receptor 4 (TLR4) inhibition through its effect on TLR4 expression, Myeloid differentiation primary response 88 (MyD88), Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), secretory Interleukin-1β (IL-1β), and nitric oxide (NO) in the Lipopolysaccharides (LPS)-stimulated U-87 MG cell line. Human astrocytoma U-87 MG cell line was cultured and incubated with 10 μg/mL of LPS for 24 hours to create a neuro-inflammation model, using t...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.NO ABSTRACTPMID:36341565 | DOI:10.18502/ijaai.v21i5.11044 (Source: Iranian Journal of Allergy, Asthma and Immunology)
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.NO ABSTRACTPMID:36341565 | DOI:10.18502/ijaai.v21i5.11044 (Source: Iranian Journal of Allergy, Asthma and Immunology)
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.NO ABSTRACTPMID:36341565 | DOI:10.18502/ijaai.v21i5.11044 (Source: Iranian Journal of Allergy, Asthma and Immunology)
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.ABSTRACTDutasteride was potentially proposed to control chronic pain by Toll-Like Receptor 4 (TLR4) inhibition through its effect on TLR4 expression, Myeloid differentiation primary response 88 (MyD88), Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), secretory Interleukin-1β (IL-1β), and nitric oxide (NO) in the Lipopolysaccharides (LPS)-stimulated U-87 MG cell line. Human astrocytoma U-87 MG cell line was cultured and incubated with 10 μg/mL of LPS for 24 hours to create a neuro-inflammation model, using t...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.NO ABSTRACTPMID:36341565 | DOI:10.18502/ijaai.v21i5.11044 (Source: Iranian Journal of Allergy, Asthma and Immunology)
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.NO ABSTRACTPMID:36341565 | DOI:10.18502/ijaai.v21i5.11044 (Source: Iranian Journal of Allergy, Asthma and Immunology)
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.NO ABSTRACTPMID:36341565 | DOI:10.18502/ijaai.v21i5.11044 (Source: Iranian Journal of Allergy, Asthma and Immunology)
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research

Inhibitory Effects of Dutasteride on TLR4: An In vitro Pain Study
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):574-583. doi: 10.18502/ijaai.v21i5.11044.ABSTRACTDutasteride was potentially proposed to control chronic pain by Toll-Like Receptor 4 (TLR4) inhibition through its effect on TLR4 expression, Myeloid differentiation primary response 88 (MyD88), Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), secretory Interleukin-1β (IL-1β), and nitric oxide (NO) in the Lipopolysaccharides (LPS)-stimulated U-87 MG cell line. Human astrocytoma U-87 MG cell line was cultured and incubated with 10 μg/mL of LPS for 24 hours to create a neuro-inflammation model, using t...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Leila Taheran Hakimeh Zali Kazem Sharifi Mohsen Yazdani Mohammad Ajoudanian Mir-Shahram Safari Samira Rajaei Ali Dabbagh Source Type: research