Janssen Highlights Commitment to Advancing Transformative Innovations in Oncology with Scientific Updates from Deep, Diverse Pipeline and Portfolio at ASCO and EHA Virtual Scientific Programs
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 30 company-sponsored studies, including six oral presentations, will be featured during the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, June 4-8. Janssen presentations will include new data and updates for both approved and investigational therapeutics that are being studied for the treatment of various solid tumors and blood cancers. Immediately following ASCO, additional data will be featured during the European Hematology Association (EHA) Virtual Congress, June 9-17. A comp...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
Updated Data Demonstrate Significant Improvement in Hematologic Complete Response with DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) in Patients with Newly Diagnosed Light Chain (AL) Amyloidosis
RARITAN, N.J., May 26, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced updated results from the Phase 3 ANDROMEDA study, which evaluated DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) for the treatment of patients with newly diagnosed light chain (AL) amyloidosis, a rare blood cell disorder associated with the deterioration of vital organs, most notably the heart, kidneys and liver.[1] Longer-term results from a median follow-up of 20.3 months showed rates of hematologic complete response (hemCR) remained significantly higher in patients treated with DARZALEX FASPRO® in combi...
Source: Johnson and Johnson - May 26, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
What are Common Causes of Anaphylaxis?
Discussion
Anaphylaxis is a potentially life-threatening hypersensitivity reaction of the body. Usually anaphylaxis is IgE mediated but complement-mediated immune complex reactions or IgG mediated reactions can cause anaphylaxis. Usually mucous membranes or skin are involved, but it is a systemic disease process with at least 2 systems involved (respiratory is second most common followed by gastrointestinal system). The epidemiology is difficult to discern but the estimated incidence is about 50-112 episodes per 100,000 person-years and estimated prevalence is 0.3-5.1%. There is data supporting an increased incidence. Over...
Source: PediatricEducation.org - May 17, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Covid vaccine: Anaphylaxis is a severe allergic reaction with these four symptoms to know
COVID vaccines side effects can be far more serious and possibly life threatening if suffering with allergies. There are four warning side effects prompting a case of anaphylaxis. (Source: Daily Express - Health)
Source: Daily Express - Health - May 16, 2021 Category: Consumer Health News Source Type: news
Main Causes of Food-Induced Anaphylaxis Identified Main Causes of Food-Induced Anaphylaxis Identified
Most triggers remain the same, but soybean may be less important.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 7, 2021 Category: Consumer Health News Tags: Allergy & Clinical Immunology News Source Type: news
Postmortem diagnostics of assumed suicidal food anaphylaxis in prison: a unique case of anaphylactic death due to peach ingestion - Tambuzzi S, Gentile G, Boracchi M, Di Candia D, Bianchi R, Zoja R.
Suicidal ingestion of food which the victim is aware they are allergic to is an exceptional occurrence in the forensic field. To the best of our knowledge, no cases of suicidal food anaphylaxis have been reported to date. Therefore we present the first cas... (Source: SafetyLit)
Source: SafetyLit - May 5, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Prevalence of mastocytosis and hymenoptera venom allergy in the United States - Schuler CF, Volertas S, Khokhar D, Yuce H, Chen L, Baser O, Montejo JM, Akin C.
BACKGROUND: Mastocytosis is a risk factor for hymenoptera venom anaphylaxis (HVA). Current guidelines recommend measuring tryptase in HVA patients and that those with mastocytosis pursue lifelong venom immunotherapy (VIT). Available data on HVA and mastocy... (Source: SafetyLit)
Source: SafetyLit - April 27, 2021 Category: International Medicine & Public Health Tags: Non-Human Animals and Insects Source Type: news
5 Takeaways From the New Food Allergy Law
Sesame becomes a “major allergen,” joining milk, eggs, fish, shellfish, tree nuts, peanuts, wheat and soybeans. (Source: NYT Health)
Source: NYT Health - April 26, 2021 Category: Consumer Health News Authors: Eric Athas Tags: Allergies Labeling and Labels (Product) Peanuts Anaphylactic Shock Food Content Type: Service Law and Legislation Sesame Seeds Food and Drug Administration Source Type: news
Use of the J & J Vaccine for COVID-19 Can Resume, Says CDC Review Panel
In a 10 to 4 vote, a committee of the U.S. Centers for Disease Control (CDC) on April 23 decided to lift the temporary hold on using the COVID-19 vaccine made by Johnson & Johnson/Janssen. The U.S. Food and Drug Administration (FDA) and CDC had temporarily halted vaccination with the J&J shot on April 13 after six reports of unusual blood clots in the brain occurred among nearly 7 million people vaccinated with the shot in the U.S.
The panel of 15 independent experts was under some pressure to make a decision about the safety of the vaccine, which is the only single-shot vaccine for COVID-19 currently authorized in...
Source: TIME: Health - April 23, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news
Anaphylaxis Case After mRNA Vaccination Traced to Polyethylene Glycol Allergy Anaphylaxis Case After mRNA Vaccination Traced to Polyethylene Glycol Allergy
An undiagnosed polyethylene glycol allergy was at the root of at least one anaphylaxis case associated with an mRNA-based COVID-19 vaccine, a UK report suggests.Reuters Health Information (Source: Medscape Emergency Medicine Headlines)
Source: Medscape Emergency Medicine Headlines - April 13, 2021 Category: Emergency Medicine Tags: Infectious Diseases News Source Type: news
FDA Approves Xolair (omalizumab) Prefilled Syringe for Self-Injection Across All Indications
● Xolair for self-injection offers healthcare providers and appropriate patients another administration option for more flexibility in managing their treatmentBasel, 13 April 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved the company ’s supplemental Biologics License Application for Xolair® (omalizumab) prefilled syringe for self-injection across all approved U.S. indications.1 Xolair is the only FDA-approved biologic designed to target and block immunoglobulin E (IgE) for the treatment of moderate to severe persistent allergic asthma, chronic...
Source: Roche Media News - April 13, 2021 Category: Pharmaceuticals Source Type: news
FDA Approves Xolair (omalizumab) Prefilled Syringe for Self-Injection Across All Indications
● Xolair for self-injection offers healthcare providers and appropriate patients another administration option for more flexibility in managing their treatmentBasel, 13 April 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved the company ’s supplemental Biologics License Application for Xolair® (omalizumab) prefilled syringe for self-injection across all approved U.S. indications.1 Xolair is the only FDA-approved biologic designed to target and block immunoglobulin E (IgE) for the treatment of moderate to severe persistent allergic asthma, chronic...
Source: Roche Investor Update - April 13, 2021 Category: Pharmaceuticals Source Type: news
New insights on cause of anaphylaxis following COVID-19 vaccination
(Wiley) On the first day of the UK campaign for COVID-19 vaccination, there were reports of two cases of anaphylaxis a severe, potentially life-threatening allergic reaction within minutes of administration of the Pfizer/BioNTech mRNA vaccine. Subsequently further cases of suspected anaphylaxis to the Pfizer vaccine were reported. A new report published in Clinical& Experimental Allergy reveals that an allergy to the ingredient polyethylene glycol (PEG) is a cause of anaphylaxis to the vaccine. However, this is in the context of millions of doses safely administered. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 7, 2021 Category: Infectious Diseases Source Type: news
Allergic Reactions, Anaphylaxis After Moderna COVID-19 Vaccine Allergic Reactions, Anaphylaxis After Moderna COVID-19 Vaccine
This report summarizes the clinical and epidemiologic characteristics of allergic reactions, including anaphylaxis and nonanaphylaxis reactions, after receipt of the Moderna COVID-19 vaccine.Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 29, 2021 Category: Consumer Health News Tags: Public Health & Prevention Journal Article Source Type: news
Anaphylaxis After First Dose of Pfizer COVID-19 Vaccine Anaphylaxis After First Dose of Pfizer COVID-19 Vaccine
This report outlines their clinical and epidemiologic characteristics.Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 15, 2021 Category: Consumer Health News Tags: Public Health & Prevention Journal Article Source Type: news
