The Efficacy of VESPA 2.0 for Cognitive Rehabilitation in Patients With Mild Cognitive Impairment
Conditions: Neurodegenerative Diseases; Cognitive Decline; Parkinson Disease Dementia; Alzheimer Disease; Multiple Sclerosis Interventions: Device: Vespa software Sponsors: IRCCS Centro Neurolesi " Bonino-Pulejo " Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

Polymorphism of ApoE in Alzheimer's Disease: Genetic Study in Castile and Leon (Spain)
Conditions: Alzheimer Disease Interventions: Diagnostic Test: Kit Buccal swab collection& stabilization de Canvax ®; Other: Cholesterol levels according to ApoE Genotype; Other: Assessing cardiovascular risk factors in all participants Sponsors: Universidad de Le ón; Consejo General de Colegios Oficiales de Enfermería España Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials

DORA and LP in Alzheimer's Disease Biomarkers
Conditions: Alzheimer Disease Interventions: Drug: Lemborexant 10 mg; Drug: Lemborexant 20mg; Drug: Placebo Sponsors: Washington University School of Medicine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials

Supporting Our Caregivers In ADRD Learning (SOCIAL)
Conditions: Alzheimer ' s Disease and Related Dementias; Quality of Life; Caregiver Stress Interventions: Behavioral: Mindful and Self-Compassionate Care Program (MASC); Behavioral: Health Education Program (HEP) Sponsors: Massachusetts General Hospital; National Institute on Aging (NIA); University of California, San Francisco Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials

Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease
Conditions: Alzheimer Disease, Early Onset Interventions: Drug: BMS-986446; Other: Placebo Sponsors: Bristol-Myers Squibb Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2024 Category: Research Source Type: clinical trials

Toolkit for Experiential Well-beiNg in Dementia (TEND)
Conditions: Dementia; Alzheimer Disease Interventions: Other: Isle of TEND Intervention Sponsors: Massachusetts General Hospital; Robert Wood Johnson Foundation Withdrawn (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials

Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease
Conditions: Alzheimer Disease; Chronic Traumatic Encephalopathy Interventions: Drug: [F-18]Flornaptitril Sponsors: CereMark Pharma, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 12, 2024 Category: Research Source Type: clinical trials

Otsuka Announces Phase 3 Topline Results of AVP-786 in the Treatment of Agitation Associated With Dementia Due to Alzheimer ’s Disease
PRINCETON, N.J. and TOKYO, JAPAN February 12, 2024– Otsuka Pharmaceutical Development& Commercialization, Inc., (OPDC) and our parent company Otsuka Pharmaceutical, Co. Ltd. (Otsuka) announce topline results of the phase 3 clinical trial... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - February 12, 2024 Category: Pharmaceuticals Source Type: clinical trials

Patient-Centered Dementia Care Practice Coaching Intervention
Conditions: Dementia; Alzheimer Disease Interventions: Behavioral: Coaching Group Sponsors: Alzheimer ' s Disease and Related Disorders Association, Inc; University of Washington Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 8, 2024 Category: Research Source Type: clinical trials

Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)
Conditions: Alzheimer Disease; Cognitive Impairment; Mild Cognitive Impairment; Dementia, Mild; Dementia Moderate; Dementia Alzheimers; Dementia of Alzheimer Type; AD Interventions: Device: Sensory Stimulation System (GS120) - Active Sponsors: Cognito Therapeutics, Inc. Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials

Attenuation of Postprandial Inflammatory Processes in Alzheimer's Disease Patients by Consumption of Pomace Oil
Conditions: Alzheimer ' s Disease Interventions: Dietary Supplement: Consumption of olive pomace olive oil by alzheimer ' s patients; Dietary Supplement: Consumption of high-oleic sunflower oil by alzheimer ' s patients Sponsors: Spanish National Research Council Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials

A Phase Ia/Ib, First-in-human (FIH) Study for Safety, Tolerability, Pharmacokinetics (PK), and Clinical Activity Evaluation of ADEL-Y01
Conditions: Alzheimer Disease Interventions: Drug: ADEL-Y01 - healty participants; Drug: Placebo - Healthy Participants; Drug: ADEL-Y01 - MCI/AD; Drug: Placebo - MCI/AD Sponsors: Alzheimer ' s Disease Expert Lab (ADEL), Inc.; Oscotec Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials

Open-Label Extension to a Pivotal Study of Sensory Stimulation in AD (OLE Hope Study, CA-0015)
Conditions: Alzheimer Disease; Cognitive Impairment; Mild Cognitive Impairment; Dementia, Mild; Dementia Moderate; Dementia Alzheimers; Dementia of Alzheimer Type; AD Interventions: Device: Sensory Stimulation System (GS120) - Active Sponsors: Cognito Therapeutics, Inc. Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials

The Clinical Impact of the Novel Alzheimer's Blood-based Biomarkers
Conditions: Alzheimer Disease; Cognitive Impairment; Dementia; Neurodegenerative Diseases; Frontotemporal Dementia; Lewy Body Disease; Vascular Dementia Interventions: Diagnostic Test: Early adoption of blood-based biomarkers for Alzheimer ' s disease Sponsors: Hospital del Mar Research Institute (IMIM) Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials

Aging Brain Care Virtual Program
Conditions: Dementia; Alzheimer Disease Interventions: Behavioral: Aging Brain Care Virtual Program Sponsors: Indiana University; National Institute on Aging (NIA); Regenstrief Institute, Inc.; Indiana University Health Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials