Working Memory Functioning in Alzheimer's Disease and Vascular Dementia
Conditions: Alzheimer Disease; Vascular Dementia; Mixed Dementias Interventions: Behavioral: Complex span task; Diagnostic Test: Clinical neuropsychological assessment; Diagnostic Test: Clinical neurospychological assessement Sponsors: University Hospital, Grenoble; University Grenoble Alps; Universit é Savoie Mont Blanc; Centre National de la Recherche Scientifique, France; Laboratoire de Psychologie et NeuroCognition Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2024 Category: Research Source Type: clinical trials
German Registry of Alzheimer's Disease Treated With Transcranial Pulse Stimulation
Conditions: Alzheimer Disease Interventions: Diagnostic Test: Registry Sponsors: Heinrich-Heine University, Duesseldorf; Storz Medical AG Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials
Enhancing Triadic Communication About Cognition for Older Adults With Alzheimer's Disease or Related Dementias Facing a Cancer Management Decision
Conditions: Cancer; Dementia Interventions: Behavioral: COACH-Cog Sponsors: University of Rochester; National Institute on Aging (NIA) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials
Diagnostic Performance of Plasma Biomarkers of Alzheimer's Disease Compared With CSF Markers
Conditions: Alzheimer Blood Biomarkers Interventions: Diagnostic Test: Blood ponction Sponsors: Central Hospital, Nancy, France; Th érèse Jonveaux; Laure Joly; Lucie Hopes; Maia Simon; Franck Schreiner Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
Long-term Extension of Phase 3 Study of ALZ- 801 in APOE4/4 Early AD Subjects
Conditions: Early Alzheimer ' s Disease Interventions: Drug: Experimental: ALZ-801 Sponsors: Alzheon Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
Oral Enteral Nutrition Feeding in Alzheimer's Patients
Conditions: Alzheimer Disease Interventions: Behavioral: Conventional Care; Device: Intermittent Oral-esophageal Tube Feeding; Device: Nasogastric tube Sponsors: Muhammad Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials
A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
Conditions: Alzheimer Disease Interventions: Drug: LY3954068; Drug: Placebo; Drug: Flortaucipir F18 Sponsors: Eli Lilly and Company Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
The BRAIN App (Phase 2 SBIR)
Conditions: Dementia; Alzheimer Disease; Vascular Dementia Interventions: Behavioral: The BRAIN App Sponsors: Hopeful Aging Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
Application of AI Technology for the Diagnosis and Treatment of Geriatric Diseases
Conditions: Parkinson Disease; Alzheimer Disease; Nervous System Diseases; Geriatric Diseases Interventions: Other: Handwriting, gait, speech, eye movements, biological samples (blood, urine, stool, saliva, etc.), images, EEG, and other relevant markers Sponsors: Qilu Hospital of Shandong University; Shandong University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2024 Category: Research Source Type: clinical trials
Autonomic Involvement in Patient With Cognitive Decline
Conditions: Dementia, Mild; Dementia of Alzheimer Type Interventions: Device: Sudoscan Sponsors: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials
DMB-I in the Treatment of Alzheimer Type Dementia
Conditions: Alzheimer Disease; Dementia of Alzheimer Type Interventions: Drug: DMB-I (Dimebon); Other: Placebo Sponsors: Bigespas LTD Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials
Small Steps Towards Improving Activity and Sleep Habits to Decrease the Risk of Dementia
Conditions: Dementia; Alzheimer Disease Interventions: Behavioral: Small Steps Program; Behavioral: Comparator Program Sponsors: University of South Australia; Flinders University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials
A proof of concept phase II study with the PDE-4 inhibitor roflumilast in patients with mild cognitive impairment or mild Alzheimer ’s disease dementia (ROMEMA): study protocol of a double-blind, randomized, placebo-controlled, between-subjects trial
DiscussionThe outcomes of the present study aim to elucidate the significance of the PDE4 inhibition mechanism as a prospective therapeutic target for enhancing cognitive function in individuals with (a)MCI and mild AD dementia. Identifying positive effects within these patient cohorts could extend the relevance of this treatment to encompass a broader spectrum of neurological disorders.Trial registrationThe Medical Ethics Committee of MUMC + granted ethics approval for the 4th version of the protocol on September 10th, 2020. The trial was registered at the European Drug Regulatory Affairs Clinical Trials (EudraCT) re...
Source: Trials - March 4, 2024 Category: Research Source Type: clinical trials
Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia Taking Stable Donepezil Treatment (MK-1167-007)
Conditions: Alzheimer ' s Disease Interventions: Drug: MK-1167; Drug: Donepezil; Drug: Placebo Sponsors: Merck Sharp& Dohme LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 29, 2024 Category: Research Source Type: clinical trials
Feasibility of Lecanemab Registry and Clinical Outcome Measures
Conditions: Alzheimer Disease Interventions: Drug: Lecanemab Sponsors: HealthPartners Institute Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 29, 2024 Category: Research Source Type: clinical trials
