Same as it ever was: Antivaccine crank Bill Maher loves him some HIV/AIDS quackery
I know I must be getting older because of Friday nights. I also know that I’m getting older because (1) there was no new post yesterday and (2) even today this post will look familiar to a significant number of our readership. Mea culpa, but trying to put the finishing touches on two R01 grants… (Source: Respectful Insolence)
Source: Respectful Insolence - February 3, 2016 Category: Surgery Authors: Orac Tags: Antivaccine nonsense Complementary and alternative medicine Quackery Television Bill Maher Charlie Sheen HBO HIV/AIDS induced remission therapy nemesis theory Real Time With Bill Maher Richard Dawkins Award Samir Chachoua vaccine Source Type: blogs

Will the Pharmaceutical Industry Learn From Past Mistakes?
By SOEREN MATTKE, MD Awash in negative headlines, public condemnation and government scrutiny, the pharmaceutical industry faces a public relations problem that, left untreated, could bring new regulations or sanctions either from governments or the courts. At the same time, though, the recent scandals over price gouging could offer an opportunity for responsible, research-based companies to distance themselves from the profiteers. The industry has come under fire at a time of unprecedented innovation. As a physician who trained in the 1990s, I am in awe of the recent breakthroughs. Immuno-oncology drugs like Keytruda (pem...
Source: The Health Care Blog - January 22, 2016 Category: Consumer Health News Authors: Simon Nath Tags: THCB Soeren Mattke Source Type: blogs

Fixing peer review
I’ve frequently noted that one of the things most detested by quacks and promoters of pseudoscience is peer review. Creationists hate peer review. HIV/AIDS denialists hate it. Anti-vaccine cranks like those at Age of Autism hate it. Indeed, as blog bud Mark Hoofnagle Mark Hoofnagle, pointed out several years ago, pseudoscientists and cranks of all… (Source: Respectful Insolence)
Source: Respectful Insolence - December 28, 2015 Category: Surgery Authors: Orac Tags: Clinical trials Medicine Science Skepticism/critical thinking peer review Richard Horton sacred cow Source Type: blogs

The Time Is Now For A Consumer Health Movement
Throughout history, social movements have galvanized wide-scale improvements in population health and quality of life. HIV/AIDS activists banded together to strengthen social services for patients, educate the public about the disease, and compel research and treatment investments that have relegated the condition to a chronic, manageable disease. The Susan G. Komen Breast Cancer Foundation (now called simply Susan G. Komen) brought the issue of breast cancer out of the shadows, raising billions of dollars and saving lives by making whole families aware of the importance of prevention and early detection. Thanks to Mothers...
Source: Health Affairs Blog - September 3, 2015 Category: Health Management Authors: Karen Wolk Feinstein Tags: GrantWatch Health Professionals Population Health Quality Consumers Health Philanthropy Health Promotion and Disease PreventionGW HPV Patient Engagement Physicians Pittsburgh Source Type: blogs

Profit over Safety – Centers for Disease Control Names 271 New Vaccinations
Conclusion How many vaccinations will be considered to be a sensible number? If all of the vaccinations currently under development are deemed a success, how many of them will be added to the schedule? As there is little research to determine which ingredients are in the vaccinations listed as “under development” by the CDC, many parents are concerned about their toxicity and how best to protect their children. I will leave you with the wise words of Robert F, Kennedy Jr: “Vaccine industry money has neutralized virtually all of the checks and balances that once stood between a rapacious pharmaceutical industry and ou...
Source: vactruth.com - August 3, 2015 Category: Allergy & Immunology Authors: Christina England Tags: Christina England Logical Top Stories Centers for Disease Control (CDC) PhRMA Robert F. Kennedy Jr. World Health Organization (WHO) Source Type: blogs

Permissive vaccines and viral virulence
A permissive vaccine prevents disease in the immunized host, but does not block virus infection. Would a permissive vaccine lead to the emergence of more virulent viruses? This hypothesis is based on the notion that viruses which kill their hosts too quickly are not efficiently transmitted, and are therefore removed by selection. However a vaccine that prevents disease, but not viral replication in the host, would allow virulent viruses to be maintained in the host population. It has been suggested that in this scenario, viruses with increased virulence would be selected if such a property aids transmission between hosts....
Source: virology blog - July 30, 2015 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information chicken evolution imperfect vaccine leaky vaccine Marek's disease MDV permissive vaccine poultry transmission viral virulence virus Source Type: blogs

Investigators vs. Industry In Clinical Research: Guiding The Hand That Treats Us
The objective was to determine whether the firm should adopt a new research strategy and invest corporate resources into the development of novel therapeutics in this area. As the intense two-day meeting progressed, it was clear that there are a number of kidney diseases for which there is a pressing need for better treatments. The panelists, all of whom were full-time faculty at university-based medical centers and directly involved in patient care, had a broad array of expertise in the laboratory and clinical investigation of glomerular disease. They forthrightly recognized gaps in knowledge, the frequent lack of identi...
Source: Health Affairs Blog - June 17, 2015 Category: Health Management Authors: Howard Trachtman and Arthur Caplan Tags: Costs and Spending Drugs and Medical Technology Featured Health Professionals Population Health genomics Industry Research Source Type: blogs

The Trans-Pacific Partnership: A Threat To Global Health?
Lost in the political discussions over the passage of the Trans-Pacific Partnership (TPP)—a trade agreement currently being negotiated in secret between the U.S. and 11 other Pacific-Rim nations—is the very real negative impact it would have on global health. Doctors Without Borders/Médecins Sans Frontières (MSF) works in over 60 countries, and our medical teams rely on access to affordable medicines and vaccines. We are deeply concerned that the TPP, in its current form, will lock-in high, unsustainable drug prices, block or delay the availability of affordable generic medicines, and price millions of people...
Source: Health Affairs Blog - May 8, 2015 Category: Health Management Authors: Deane Marchbein Tags: Drugs and Medical Technology Equity and Disparities Featured Global Health Public Health Doctors Without Borders fair trade generic drugs obama trade deal TPP Trans-Pacific Trade Partnership Source Type: blogs

New Cures Require New Pricing Policies
One critical incentive for ongoing drug discovery and development is the temporary monopoly pricing that manufacturers can command for novel drugs. Yet this incentive, embedded in current patent and regulatory policy, does not guarantee that manufacturers will deliver novel products with clinically meaningful benefits. Indeed there are many diseases---including Alzheimer’s disease and Amyotrophic lateral sclerosis (ALS)---that pose significant patient, family, and societal burden but have not benefited from meaningful treatment advances. Meanwhile, the American public appears increasingly wary of the unintended conseque...
Source: Health Affairs Blog - April 16, 2015 Category: Health Management Authors: Rena Conti Tags: Health Policy Lab costs drugs Pharma pricing Source Type: blogs

Nickson Would be Celebrating Life if it Weren’t for Vaccines
Conclusion Parents need to be able to choose what goes into their child’s body, especially when their babies are not born full-term or have any underlying health problems at birth. When a product such as a vaccine is injected into a child, known to be associated with severe risks, including death, there should be a standard protocol in place for these families to get needed support when the risks outweigh the benefits. No one can predict how a vaccine will negatively affect a person. Lindsey and other families going through this, suffering the loss of a child likely caused by the vaccine(s) given to them, when no other p...
Source: vactruth.com - April 9, 2015 Category: Allergy & Immunology Authors: Augustina Ursino Tags: Augustina Ursino Human Top Stories National Vaccine Injury Compensation Program (NVICP) Sudden Infant Death Syndrome (SIDS) vaccine court Vaccine Death VAERS Source Type: blogs

Measles in the brain: Fusion gone awry
The entry of enveloped viruses into cells begins when the membrane that surrounds these virus particles fuse with a cell membrane. The process of virus-cell fusion must be tightly regulated, to make sure it happens in the right cells. The fusion activity of measles viruses isolated from the brains of AIDS patients is not properly regulated, which might explain why these viruses cause disease in the central nervous system. Measles virus particles bind to cell surface receptors via the viral glycoprotein HN (illustrated). Once the viral and cell membranes have been brought together by this receptor-ligand interaction, fusi...
Source: virology blog - February 18, 2015 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information cell receptor F protein fusion HN protein measles inclusion body encephalitis measles virus paramyxovirus viral Source Type: blogs

Progress in α-Synuclein Immunotherapy
The protein α-synuclein is involved in Parkinson's disease in much the same way that β-amyloid is involved in Alzheimer's disease. These particular misfolded proteins accumulate with age to form deposits in everyone's brain tissues, but this is seen to occur to a much greater extent in those suffering from the related neurodegenerative condition. There is a lot of research to suggest that this accumulation of amyloid or synuclein is driving disease pathology and death of brain cells, but equally there is a lot of research to suggest that this is far from a complete picture of all that is going wrong in the failing bioche...
Source: Fight Aging! - December 16, 2014 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

10 Reasons Not To Vaccinate
Conclusion You are on your own to try and regain your health in the event that you are vaccine injured. The expense and suffering is yours alone to face. Very few individuals will be awarded money from funds set up by the National Childhood Vaccine Injury Act. The system is designed for individuals to fail in making their claim of vaccine injury. The public pays for this injury fund in the cost of taxes on vaccinations. To learn more, read my other in-depth articles on vaccinations which have been published on VacTruth or Natural News, here: Vaccinations You may also check the resources below. Most important is to remember...
Source: vactruth.com - December 12, 2014 Category: Allergy & Immunology Authors: Michelle Goldstein Tags: Michelle Goldstein Top Stories autism National Vaccine Injury Compensation Program (NVICP) Reasons Not to Vaccinate Sudden Infant Death Syndrome (SIDS) truth about vaccines Vaccine Adverse Event Reporting System (VAERS) Source Type: blogs

The end of HIV?
I don't know why we need to have single days when we're supposed to think about stuff we probably should be thinking about regularly (e.g., why do we have National Pickle Week when pickles matter all the time?) but for what it's worth, today is World AIDS Day.The One Campaign (Bono's charity) says there's good news: we're at a "tipping point" in that the number of people newly receiving HIV treatment now exceeds the number of new infections. Furthermore, the global incidence of HIV has fallen by 40% since 2001. This is no doubt for a combination of reasons, including better awareness and changes in people's behavior, but o...
Source: Stayin' Alive - December 1, 2014 Category: American Health Source Type: blogs