Effect of GreenshellTM mussel on osteoarthritis biomarkers and inflammation in healthy postmenopausal women: a study protocol for a randomized double-blind placebo-controlled trial
This study aims to determine the effect of GSM powder on biomarkers of cartilage metabolism, bone resorption, and inflammation in New Zealand healthy overweight/obese postmenopausal women who are at early stage or at high risk of OA.MethodFifty overweight or obese (BMI 25 –35 kg/m2) postmenopausal women (aged 55 –75 years) will be recruited by advertisement. Participants will be randomized based on a double-blind randomization schedule and stratified randomization based on BMI and age distribution. The participant will be assigned with a 1:1 allocation ratio to receive 3 g/d whole meat GSM powder or p lacebo (sun...
Source: Trials - July 28, 2021 Category: Research Source Type: clinical trials
Recruiting hard-to-reach pregnant women at high psychosocial risk: strategies and costs from a randomised controlled trial
ConclusionsRecruitment resulted from a combination of all three strategies. Our reflections on the successes and challenges of these strategies highlight the need for recruitment strategies to be flexible to adapt to complex interventions and real-world challenges. These findings will inform future research in similar hard-to-reach populations.Trial registrationInternational Standard Randomised Controlled Trials Number RegistryISRCTN21656568. Retrospectively registered on 28 February 2014 (Source: Trials)
Source: Trials - June 16, 2021 Category: Research Source Type: clinical trials
Young Adults' Reactions to Low Nicotine Cigarette Advertising
Condition: Smoking Intervention: Behavioral: Advertisement condition Sponsors: University of Pennsylvania; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 28, 2021 Category: Research Source Type: clinical trials
