Study Examining the Safety and Toxicity of Stereotactic Body Radiotherapy (SBRT) Followed by PCX12 Immunotherapy Delivered by Intratumoral Injection for the Treatment of Patients With Locally Advanced Pancreatic Adenocarcinoma (LAPC)
Conditions: Pancreatic Adenocarcinoma Interventions: Drug: PCX-12 Sponsors: Haoming (Carl) Qiu Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials
Multi-omics Analysis to Characterize the Invasive Evolution of Pulmonary Subsolid Nodules
Conditions: Adenocarcinoma of Lung Interventions: Diagnostic Test: Mass spectrometry-based proteomics Sponsors: Cancer Institute and Hospital, Chinese Academy of Medical Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials
Performance of Artificial Intelligence in Colonoscopy for Right Colon Polyp Detection: a Randomized Controlled Trial
Conditions: Colon Cancer; Colon Polyp; Colon Lesion; Colon Adenocarcinoma Interventions: Procedure: Colonoscopy Sponsors: Groupe Hospitalier Diaconesses Croix Saint-Simon; Cosmo Artificial Intelligence-AI Ltd Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials
Celiac plExus Block to Reduce OpioID Consumption Following Hepato-pancreato-biliary Mini-invasive Surgery
Conditions: Pancreatic Ductal Adenocarcinoma; Liver, Cancer of, Primary Resectable Interventions: Drug: Ropivacaine 0.5%; Drug: Normal Saline Sponsors: Sixth Affiliated Hospital, Sun Yat-sen University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 19, 2024 Category: Research Source Type: clinical trials
Remote Home-Based Exercise Program for Strength Training in Endometrial Cancer Survivors in Rural Areas
Conditions: FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma; FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma; Stage IA Uterine Corpus Cancer AJCC v8; Stage IB Uterine Corpus Cancer AJCC v8 Interventions: Other: Exercise Counseling; Other: Exercise Intervention; Other: Health Promotion and Education; Other: Interview; Other: Physical Performance Testing; Other: Questionnaire Administration; Other: Telemedicine Sponsors: Mayo Clinic Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 19, 2024 Category: Research Source Type: clinical trials
A Study of IMM-6-415 in RAS/RAF Mutant Solid Tumors
Conditions: Advanced Solid Tumor (Phase 1); Pancreas Adenocarcinoma; Non-small Cell Lung Cancer; Malignant Melanoma (Cutaneous) Interventions: Drug: IMM-6-415 Sponsors: Immuneering Corporation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
A Phase 1/2a Study of IMM-6-415 in RAS/RAF Mutant Solid Tumors
Conditions: Advanced Solid Tumor (Phase 1); Pancreas Adenocarcinoma; Non-small Cell Lung Cancer; Malignant Melanoma (Cutaneous) Interventions: Drug: IMM-6-415 Sponsors: Immuneering Corporation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma
Conditions: Biochemically Recurrent Prostate Carcinoma; Oligometastatic Prostate Carcinoma; Recurrent Prostate Adenocarcinoma; Stage IIB Prostate Cancer AJCC v8; Stage IIC Prostate Cancer AJCC v8; Stage III Prostate Cancer AJCC v8; Stage IV Prostate Cancer AJCC v8 Interventions: Drug: Antiandrogen Therapy; Procedure: Biospecimen Collection; Procedure: Bone Scan; Radiation: Hypofractionated Radiation Therapy; Procedure: Magnetic Resonance Imaging; Procedure: Positron Emission Tomography; Radiation: Stereotactic Body Radiation Therapy; Other: Survey Administration Sponsors: Mayo Clinic Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
A Phase I/II Study of Intraperitoneal Paclitaxel in Patients With Metastatic Appendiceal Adenocarcinoma
Conditions: Metastatic Appendiceal Adenocarcinoma; Intraperitoneal Paclitaxel Interventions: Drug: Dexamethasone; Drug: Diphenhydramine; Drug: Famotidine; Drug: Paclitaxel Sponsors: M.D. Anderson Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
ASKB589 in Combination With CAPOX and PD-1 Inhibitor in Patients With Advanced, and Unresectable G/GEJ Cancer
Conditions: Gastroesophageal Junction Adenocarcinoma; Gastric Adenocarcinoma Interventions: Drug: ASKB589; Drug: Oxaliplatin; Drug: Capecitabine; Drug: Tislelizumab; Drug: Placebo Sponsors: AskGene Pharma, Inc.; Jiangsu Aosaikang Pharmaceutical Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
Evaluation of Infigratinib in Patients With Locally Advanced or Metastatic Gastric Cancer or GEJ Adenocarcinoma
Conditions: Gastric Cancer; Gastroesophageal Junction Adenocarcinoma Interventions: Drug: Infigratinib Sponsors: LianBio LLC Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
FL118 for Treating Patients With Advanced Pancreatic Ductal Adenocarcinoma
Conditions: Advanced Pancreatic Ductal Adenocarcinoma; Locally Advanced Pancreatic Ductal Adenocarcinoma; Metastatic Pancreatic Ductal Adenocarcinoma; Refractory Pancreatic Ductal Adenocarcinoma; Stage II Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Unresectable Pancreatic Ductal Adenocarcinoma Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Computed Tomography; Drug: DDX5 Degrader FL118; Procedure: Magnetic Resonance Imaging Sponsors: Roswell Park Cancer Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
Stereotactic Ablative Radiotherapy in Synchronous and Metachronous Oligo-Metastatic Non Small Cell Lung Cancer
Conditions: NSCLC; NSCLC Stage IV; Oligometastatic Disease; Non Small Cell Lung Cancer; Non Small Cell Lung Cancer Metastatic; EGF-R Positive Non-Small Cell Lung Cancer; NSCLC Stage IV Without EGFR/ALK Mutation; Non-Small Cell Adenocarcinoma; Non-Small Cell Squamous Lung Cancer; Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor; Synchronous Metastases; Metachronous Metastasis Interventions: Radiation: Stereotactic Ablative Radiotherapy Sponsors: Radiotherapy Oncology Centre " Santa Maria " Hospital; Paola Anselmo,MD; Michelina Casale,PhD; Fabio Trippa,MD Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, The PARAMMUNE Trial
Conditions: Advanced Esophageal Adenocarcinoma; Advanced Gastric Adenocarcinoma; Advanced Gastroesophageal Junction Adenocarcinoma; Clinical Stage II Esophageal Adenocarcinoma AJCC v8; Clinical Stage III Esophageal Adenocarcinoma AJCC v8; Clinical Stage III Gastric Cancer AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IV Esophageal Adenocarcinoma AJCC v8; Clinical Stage IV Gastric Cancer AJCC v8; Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8; Metastatic Esophageal Adenocarcinoma; Metastatic Gastric Adenocarcinoma; Metastatic Gastroesophageal Junction Adenoc...
Source: ClinicalTrials.gov - January 12, 2024 Category: Research Source Type: clinical trials
Reduction of Gastrointestinal Toxicity in Prostate Cancer by Proton Spot Placement
Conditions: Prostate Cancer; Prostate Adenocarcinoma; Prostate Carcinoma Interventions: Radiation: Spot Delete planning for proton therapy; Radiation: Traditional proton treatment planning system Sponsors: Thompson Cancer Survival Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials
