WCD: Dapsone gel effective for acne in women of color
VANCOUVER – Dapsone gel 5% proved effective and well tolerated for facial acne in women with skin of color in a multicenter pilot study.
The study was conducted because even though dapsone gel 5% (Aczone) is approved for the treatment of acne on the strength of two pivotal randomized,...googletag.display('div-gpt-ad-cta'); (Source: Skin and Allergy News)
Source: Skin and Allergy News - July 10, 2015 Category: Dermatology Source Type: news
Acne Gel Linked to Rare Side Effect, Doctors Warn
Teen developed blood disorder after using Aczone for a week (Source: WebMD Health)
Source: WebMD Health - January 29, 2015 Category: Consumer Health News Source Type: news
What Medicines Should Be Avoided with G6PD Deficiency?
Discussion
Glucose 6-phosphate dehydrogenase deficiency (G6PD) is an X-linked disease that has multiple mutations. Each mutation causes a different amount of the enzyme to be produced within cells and therefore not all mutations will produce disease. Glucose 6-phosphate dehydrogenase is an enzyme that is critical to the metabolism of all aerobic cells as it catalyzes the rate-limiting step of the pentose phosphate pathway reducing NADP to NADPH. NADPH is important for nucleic acid replication and therefore cell division. G6PD is the only source of NADPH within the cell, so deficiency makes red blood cells susceptible to he...
Source: PediatricEducation.org - September 15, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Dapsone (Dapsone) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 19, 2014 Category: Drugs & Pharmacology Source Type: news
Singapore scientists lead in the discovery of gene responsible for fatal drug allergy
A team of researchers led by Prof Liu Jianjun from A*STAR's Genome Institute of Singapore (GIS) has discovered that the presence of a gene allele known as HLA-B*13:01 could cause a severe adverse drug reaction (ADR1) to dapsone, which could be fatal. The important discovery will lead to the development of HLA-B*13:01-based diagnostic tests, which will identify high-risk individuals of this potentially life-threatening condition, and help improve the safety of dapsone therapy... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 28, 2013 Category: Consumer Health News Tags: Genetics Source Type: news
What enhanced elimination techniques are useful in critical toxicology patients?
3 out of 5 stars
Enhanced Poison Elimination in Critical Care. Ghannoum M, Gosselin S. Adv Chronic Kidney Dis 2013 Jan;20:94-101.
Abstract
This survey of methods available for enhanced elimination in toxicology cases gives a good overview, but unnecessarily wastes time discussing modalities that now are never used (e.g., forced diuresis and urine acidification). The information would have been more accessible if it had been streamlined to reflect current practice. For instance, the authors list 20 poisons “amenable” to multidose activated charcoal, but in fact the indications for this treatment are limited and...
Source: The Poison Review - February 17, 2013 Category: Toxicology Authors: Leon Tags: Medical critical care enhanced elimination hemodialysis multidose activated charcoal overdose poisoning toxicology Source Type: news
